Publications by authors named "Barbara Filipek"

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KM-408, a novel phenoxyalkyl derivative as a potential anticonvulsant and analgesic compound for the treatment of neuropathic pain.
Anna Waszkielewicz, Henryk Marona, Katarzyna Pańczyk-Straszak, Barbara Filipek, Anna Rapacz

Pharmacol Rep· February 2023

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HBK-10, A Compound with α-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats.
Klaudia Lustyk, Kinga Sałaciak, Agata Siwek, Barbara Filipek, Jacek Sapa

Pharmaceuticals (Basel)· October 2022

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Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
Paula Zaręba, Kinga Sałat, Georg C Höfner, Kamil Łątka, Marek Bajda, Barbara Filipek

Eur J Med Chem· October 2021

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Novel serotonin 5-HT receptor antagonists derived from 4-phenylcyclohexane-5-spiro-and 5-methyl-5-phenyl-hydantoin, for use as potential antiplatelet agents.
Anna Czopek, Monika Kubacka, Adam Bucki, Agata Siwek, Barbara Filipek

Pharmacol Rep· October 2021

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Bioresearch of New 1-pyrrolo[3,4-c]pyridine-1,3(2)-diones.
Dominika Szkatuła, Edward Krzyżak, Szczepan Mogilski, Jacek Sapa, Barbara Filipek

Molecules· December 2020

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KM-416, a novel phenoxyalkylaminoalkanol derivative with anticonvulsant properties exerts analgesic, local anesthetic, and antidepressant-like activities. Pharmacodynamic, pharmacokinetic, and forced degradation studies.
Monika Kubacka, Anna Rapacz, Kinga Sałat, Barbara Filipek, Agnieszka Cios

Eur J Pharmacol· November 2020

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Can Lipoic Acid Attenuate Cardiovascular Disturbances Induced by Ethanol and Disulfiram Administration Separately or Jointly in Rats?
Anna Bilska-Wilkosz, Magdalena Kotańska, Magdalena Górny, Barbara Filipek, Małgorzata Iciek

Oxid Med Cell Longev· June 2020

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Antinociceptive, antiedematous, and antiallodynic activity of 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-dione derivatives in experimental models of pain.
Anna Dziubina, Dominika Szkatuła, Joanna Gdula-Argasińska, Magdalena Kotańska, Barbara Filipek

Naunyn Schmiedebergs Arch Pharmacol· May 2020

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Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain.
Anna Rapacz, Sabina Rybka, Jolanta Obniska, Aleksandra Jodłowska, Małgorzata Góra, Barbara Filipek

Eur J Pharmacol· February 2020

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Is the mechanism of nitroglycerin tolerance associated with aldehyde dehydrogenase activity? A contribution to the ongoing discussion.
Anna Bilska-Wilkosz, Magdalena Kotańska, Magdalena Górny, Barbara Filipek, Małgorzata Iciek

Acta Biochim Pol· December 2019

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Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives.
Jakub Jończyk, Krzysztof Lodarski, Marek Staszewski, Justyna Godyń, Paula Zaręba, Barbara Filipek

Bioorg Chem· September 2019

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Reversal of cardiac, vascular, and renal dysfunction by non-quinazoline α1-adrenolytics in DOCA-salt hypertensive rats: a comparison with prazosin, a quinazoline-based α1-adrenoceptor antagonist.
Monika Kubacka, Monika Zadrożna, Barbara Nowak, Magdalena Kotańska, Barbara Filipek

Hypertens Res· August 2019

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Beneficial effects of non-quinazoline α-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin.
Monika Kubacka, Magdalena Kotańska, Małgorzata Szafarz, Krzysztof Pociecha, Anna M Waszkielewicz, Barbara Filipek

Nutr Metab Cardiovasc Dis· July 2019

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Alkyl derivatives of 1,3,5-triazine as histamine H receptor ligands.
Dorota Łażewska, Szczepan Mogilski, Stefanie Hagenow, Kamil Kuder, Monika Głuch-Lutwin, Barbara Filipek

Bioorg Med Chem· April 2019

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Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicity.
Berenika M Szczęśniak-Sięga, Szczepan Mogilski, Rafał J Wiglusz, Jan Janczak, Jadwiga Maniewska, Barbara Filipek

Bioorg Med Chem· April 2019

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HBK-17, a 5-HT Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling.
Karolina Pytka, Monika Głuch-Lutwin, Elżbieta Żmudzka, Kinga Sałaciak, Agata Siwek, Barbara Filipek

Front Pharmacol· October 2018

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Evaluation of anticonvulsant and analgesic activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides.
Anna Rapacz, Monika Głuch-Lutwin, Barbara Mordyl, Barbara Filipek, Michał Abram

Epilepsy Res· July 2018

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Involvement of the NO/sGC/cGMP/K channels pathway in vascular relaxation evoked by two non-quinazoline α-adrenoceptor antagonists.
Monika Kubacka, Magdalena Kotańska, Grzegorz Kazek, Anna Maria Waszkielewicz, Henryk Marona, Barbara Filipek

Biomed Pharmacother· July 2018

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Novel naphthyloxy derivatives - Potent histamine H receptor ligands. Synthesis and pharmacological evaluation.
Dorota Łażewska, Maria Kaleta, Stefanie Hagenow, Szczepan Mogilski, Gniewomir Latacz, Barbara Filipek

Bioorg Med Chem· May 2018

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Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice.
Anna Rapacz, Jolanta Obniska, Paulina Koczurkiewicz, Katarzyna Wójcik-Pszczoła, Agata Siwek, Barbara Filipek

Eur J Pharmacol· February 2018

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Anti-aggregation effect of aroxyalkyl derivatives of 2-methoxyphenylpiperazine is due to their 5-HT and α-adrenoceptor antagonistic properties. A comparison with ketanserin, sarpogrelate, prazosin, yohimbine and ARC239.
Monika Kubacka, Grzegorz Kazek, Magdalena Kotańska, Barbara Filipek, Anna Maria Waszkielewicz

Eur J Pharmacol· January 2018

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Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H receptor ligands.
Dorota Łażewska, Maria Kaleta, J Stephan Schwed, Tadeusz Karcz, Szczepan Mogilski, Barbara Filipek

Bioorg Med Chem· October 2017

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Analgesic, antiallodynic, and anticonvulsant activity of novel hybrid molecules derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide in animal models of pain and epilepsy.
Anna Rapacz, Krzysztof Kamiński, Jolanta Obniska, Paulina Koczurkiewicz, Elżbieta Pękala, Barbara Filipek

Naunyn Schmiedebergs Arch Pharmacol· June 2017

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The role of melatonin, neurokinin, neurotrophic tyrosine kinase and glucocorticoid receptors in antidepressant-like effect.
Karolina Pytka, Katarzyna Młyniec, Karolina Podkowa, Adrian Podkowa, Magdalena Jakubczyk, Barbara Filipek

Pharmacol Rep· June 2017

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Synthesis and evaluation of anticonvulsant properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and its 3-methyl-, 3-isopropyl, and 3-benzhydryl analogs.
Sabina Rybka, Jolanta Obniska, Anna Rapacz, Barbara Filipek, Paweł Żmudzki

Bioorg Med Chem Lett· March 2017

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