Publications by authors named "Barbara Hempstead"

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Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer's disease.
Vanessa Schmidt, Ewelina Ziemlinska, Tomasz Obrebski, Jemila P Gomes, Ewa Zurawska-Plaksej, Barbara L Hempstead

Nat Commun· October 2025

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Immune activation of the p75 neurotrophin receptor: implications in neuroinflammation.
Victor Danelon, Sarah C Garret-Thomson, Steven C Almo, Francis S Lee, Barbara L Hempstead

Front Mol Neurosci· December 2023

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Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor.
Nicholas C Morano, Roshelle S Smith, Victor Danelon, Ryan Schreiner, Uttsav Patel, Barbara L Hempstead

J Clin Invest· November 2022

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SorCS2 is required for social memory and trafficking of the NMDA receptor.
Jianmin Yang, Qian Ma, Iva Dincheva, Joanna Giza, Deqiang Jing, Barbara L Hempstead

Mol Psychiatry· March 2021

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Zinc induced structural changes in the intrinsically disordered BDNF Met prodomain confer synaptic elimination.
Jing Wang, Agustin Anastasia, Henrietta Bains, Joanna I Giza, David G Clossey, Barbara L Hempstead

Metallomics· August 2020

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BDNF Actions in the Cardiovascular System: Roles in Development, Adulthood and Response to Injury.
Pouneh Kermani, Barbara Hempstead

Front Physiol· April 2019

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A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death and .
Shayri G Greenwood, Laura Montroull, Marta Volosin, Helen E Scharfman, Kenneth K Teng, Barbara L Hempstead

eNeuro· January 2019

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New Roles for an Ancient Factor.
Francis S Lee, Barbara L Hempstead

Trends Neurosci· November 2018

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The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.
Joanna I Giza, Jihye Kim, Heidi C Meyer, Agustin Anastasia, Iva Dincheva, Barbara L Hempstead

Neuron· September 2018

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The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.
Joanna I Giza, Jihye Kim, Heidi C Meyer, Agustin Anastasia, Iva Dincheva, Barbara L Hempstead

Neuron· July 2018

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Narp Mediates Antidepressant-Like Effects of Electroconvulsive Seizures.
Andrew D Chang, Punit V Vaidya, Edward P Retzbach, Sunho J Chung, Urian Kim, Barbara L Hempstead

Neuropsychopharmacology· April 2018

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Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice.
Iva Dincheva, Jianmin Yang, Anfei Li, Tina Marinic, Helena Freilingsdorf, Barbara Hempstead

Am J Psychiatry· December 2017

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SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
Qian Ma, Jianmin Yang, Teresa A Milner, Jean-Paul G Vonsattel, Mary Ellen Palko, Barbara L Hempstead

JCI Insight· May 2017

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Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery.
Ajay X Thomas, Yasmin Cruz Del Angel, Marco I Gonzalez, Andrew J Carrel, Jessica Carlsen, Barbara L Hempstead

eNeuro· October 2016

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Autocrine BDNF-TrkB signalling within a single dendritic spine.
Stephen C Harward, Nathan G Hedrick, Charles E Hall, Paula Parra-Bueno, Teresa A Milner, Barbara L Hempstead

Nature· October 2016

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Brain-Derived Neurotrophic Factor: Three Ligands, Many Actions.
Barbara L Hempstead

Trans Am Clin Climatol Assoc· June 2016

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Effects of the BDNF Val66Met Polymorphism on Anxiety-Like Behavior Following Nicotine Withdrawal in Mice.
Bridgin G Lee, Agustin Anastasia, Barbara L Hempstead, Francis S Lee, Julie A Blendy

Nicotine Tob Res· December 2015

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Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease.
Qian Ma, Jianmin Yang, Thomas Li, Teresa A Milner, Barbara L Hempstead

Neurobiol Dis· October 2015

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Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation.
Agustin Anastasia, Phillip A Barker, Moses V Chao, Barbara L Hempstead

J Neurosci· August 2015

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3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways.
Peter DelNero, Maureen Lane, Scott S Verbridge, Brian Kwee, Pouneh Kermani, Barbara Hempstead

Biomaterials· July 2015

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p75NTR, but not proNGF, is upregulated following status epilepticus in mice.
Melissa W VonDran, John LaFrancois, Victoria A Padow, Wilma J Friedman, Helen E Scharfman, Barbara L Hempstead

ASN Neuro· June 2015

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Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling.
Minseok Song, Joanna Giza, Catia C Proenca, Deqiang Jing, Mark Elliott, Barbara L Hempstead

Dev Cell· June 2015

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Astrocyte-derived BDNF supports myelin protein synthesis after cuprizone-induced demyelination.
Clifton G Fulmer, Melissa W VonDran, Althea A Stillman, Yangyang Huang, Barbara L Hempstead

J Neurosci· June 2014

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proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus.
Jianmin Yang, Lauren C Harte-Hargrove, Chia-Jen Siao, Tina Marinic, Roshelle Clarke, Barbara L Hempstead

Cell Rep· May 2014

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Mir-592 regulates the induction and cell death-promoting activity of p75NTR in neuronal ischemic injury.
Krithi Irmady, Katherine A Jackman, Victoria A Padow, Neelam Shahani, Laura Andres Martin, Barbara L Hempstead

J Neurosci· February 2014

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