Publications by authors named "Barbara Renga"

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Non invasive prenatal diagnosis of fetal aneuploidy using cell free fetal DNA.
Barbara Renga

Eur J Obstet Gynecol Reprod Biol· June 2018

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Platelets and cardiovascular risk.
Barbara Renga, Franco Scavizzi

Acta Cardiol· February 2017

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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.
Claudia Finamore, Carmen Festa, Barbara Renga, Valentina Sepe, Adriana Carino

Sci Rep· July 2016

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Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.
Barbara Renga, Sabrina Cipriani, Adriana Carino, Michele Simonetti, Angela Zampella

PLoS One· June 2016

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Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling.
Sabrina Cipriani, Barbara Renga, Claudio D'Amore, Michele Simonetti, Antonio Angelo De Tursi

PLoS One· April 2016

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Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.
Valentina Sepe, Barbara Renga, Carmen Festa, Claudia Finamore, Dario Masullo

Steroids· January 2016

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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.
Valentina Sepe, Carmen Festa, Barbara Renga, Adriana Carino, Sabrina Cipriani

Sci Rep· January 2016

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Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism.
Francesco Saverio Di Leva, Carmen Festa, Barbara Renga, Valentina Sepe, Ettore Novellino

Sci Rep· November 2015

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The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.
Barbara Renga, Daniela Francisci, Adriana Carino, Silvia Marchianò, Sabrina Cipriani

Sci Rep· October 2015

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Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa.
Eleonora Distrutti, Luca Santucci, Sabrina Cipriani, Barbara Renga, Elisabetta Schiaroli

J Gastroenterol· July 2015

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Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Barbara Renga, Mariarosaria Bucci, Sabrina Cipriani, Adriana Carino, Maria Chiara Monti

Am J Physiol Heart Circ Physiol· July 2015

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Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP.
Eleonora Distrutti, Julie-Ann O'Reilly, Claire McDonald, Sabrina Cipriani, Barbara Renga

PLoS One· May 2015

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Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice.
Hiroyuki Tsuchiya, Kerry-Ann da Costa, Sangmin Lee, Barbara Renga, Hartmut Jaeschke

Gastroenterology· May 2015

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Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists.
Barbara Renga, Carmen Festa, Simona De Marino, Simone Di Micco, Maria Valeria D'Auria

Steroids· April 2015

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The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2.
Barbara Renga, Daniela Francisci, Elisabetta Schiaroli, Adriana Carino, Sabrina Cipriani

PLoS One· January 2015

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Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.
Carmen Festa, Barbara Renga, Claudio D'Amore, Valentina Sepe, Claudia Finamore

J Med Chem· October 2014

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Modification on ursodeoxycholic acid (UDCA) scaffold. discovery of bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 (GP-BAR1).
Valentina Sepe, Barbara Renga, Carmen Festa, Claudio D'Amore, Dario Masullo

J Med Chem· September 2014

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Incisterols, highly degraded marine sterols, are a new chemotype of PXR agonists.
Giuseppina Chianese, Valentina Sepe, Vittorio Limongelli, Barbara Renga, Claudio D'Amore

Steroids· May 2014

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Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation.
Valentina Sepe, Francesco Saverio Di Leva, Claudio D'Amore, Carmen Festa, Simona De Marino, Barbara Renga

Mar Drugs· May 2014

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Structural insights into Estrogen Related Receptor-β modulation: 4-methylenesterols from Theonella swinhoei sponge as the first example of marine natural antagonists.
Simone Di Micco, Barbara Renga, Adriana Carino, Maria Valeria D'Auria, Angela Zampella

Steroids· February 2014

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Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors.
Claudio D'Amore, Francesco Saverio Di Leva, Valentina Sepe, Barbara Renga, Chiara Del Gaudio

J Med Chem· February 2014

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Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges.
Valentina Sepe, Claudio D'Amore, Raffella Ummarino, Barbara Renga, Maria Valeria D'Auria

Eur J Med Chem· February 2014

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In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitors.
Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Daniela Francisci

Eur J Pharmacol· January 2014

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Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.
Andrea Mencarelli, Claudio D'Amore, Barbara Renga, Sabrina Cipriani, Adriana Carino

Mar Drugs· December 2013

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CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination.
Andrea Mencarelli, Luigina Graziosi, Barbara Renga, Sabrina Cipriani, Claudio D'Amore

Transl Oncol· December 2013

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