Publications by authors named "Barry A Springer"

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4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors.
Guozhang Xu, Marta C Abad, Peter J Connolly, Michael P Neeper, Geoffrey T Struble, Barry A Springer

Bioorg Med Chem Lett· August 2008

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Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases.
Guozhang Xu, Lily Lee Searle, Terry V Hughes, Amanda K Beck, Peter J Connolly, Barry A Springer

Bioorg Med Chem Lett· June 2008

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Enhancing recombinant protein quality and yield by protein stability profiling.
Tara M Mezzasalma, James K Kranz, Winnie Chan, Geoffrey T Struble, Céline Schalk-Hihi, Barry A Springer

J Biomol Screen· April 2007

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Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.
Carsten Schubert, Céline Schalk-Hihi, Geoffrey T Struble, Hong-Chang Ma, Ioanna P Petrounia, Barry A Springer

J Biol Chem· February 2007

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Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.
Céline Schalk-Hihi, Hong-Chang Ma, Geoffrey T Struble, Shariff Bayoumy, Robyn Williams, Barry A Springer

J Biol Chem· February 2007

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Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity.
Jukka Kervinen, Hongchang Ma, Shariff Bayoumy, Carsten Schubert, Cynthia Milligan, Barry A Springer

Arch Biochem Biophys· May 2006

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Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology.
Andrew J Leitz, Timothy H Bayburt, Alexander N Barnakov, Barry A Springer, Stephen G Sligar

Biotechniques· May 2006

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Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology.
Theodore E Carver, Brian Bordeau, Maxwell D Cummings, Eugene C Petrella, Michael J Pucci, Barry A Springer

J Biol Chem· March 2005

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2-Hydroxy-4,6-diamino-[1,3,5]triazines: a novel class of VEGF-R2 (KDR) tyrosine kinase inhibitors.
Nand Baindur, Naresh Chadha, Benjamin M Brandt, Davoud Asgari, Raymond J Patch, Barry A Springer

J Med Chem· March 2005

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