Publications by authors named "Barry Cooperman"

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Near-cognate tRNAs enhance tRNA rejection and prime the ribosome for rapid subsequent tRNA testing.
Clark Fritsch, Arpan Bhattacharya, Martin Y Ng, Hong Li, Philip C Nelson, Barry S Cooperman

Biophys J· December 2025

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Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases.
Saleem Y Bhat, Arpan Bhattacharya, Hong Li, Xiaonan Cui, John D Lueck, Barry S Cooperman

Nucleic Acids Res· March 2025

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Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases.
Saleem Bhat, Arpan Bhattacharya, Hong Li, Xianon Cui, John D Lueck, Barry S Cooperman

bioRxiv· December 2024

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Single-Molecule Studies of Cognate and Near-Cognate Elongation in an Eukaryotic Translation System.
Clark Fritsch, Arpan Bhattacharya, Martin Y Ng, Hong Li, Philip C Nelson, Barry S Cooperman

bioRxiv· August 2024

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Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins.
Rosario Avolio, Ilenia Agliarulo, Daniela Criscuolo, Daniela Sarnataro, Margherita Auriemma, Barry S Cooperman

Genome Res· August 2023

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Assembly of the Mitochondrial Translation Initiation Complex.
Cristina Remes, Minh Duc Nguyen, Henrik Spahr, Martin Ng, Clark Fritsch, Barry Cooperman

Methods Mol Biol· May 2023

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Human mitochondria require mtRF1 for translation termination at non-canonical stop codons.
Annika Krüger, Cristina Remes, Dmitrii Igorevich Shiriaev, Yong Liu, Henrik Spåhr, Barry S Cooperman

Nat Commun· January 2023

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Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria.
Cristina Remes, Anas Khawaja, Sarah F Pearce, Adam M Dinan, Shreekara Gopalakrishna, Barry Cooperman

Nucleic Acids Res· January 2023

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Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins.
Rosario Avolio, Ilenia Agliarulo, Daniela Criscuolo, Daniela Sarnataro, Margherita Auriemma, Barry Cooperman

bioRxiv· January 2023

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A High-Throughput Assay for In Vitro Determination of Release Factor-Dependent Peptide Release from a Pretermination Complex by Fluorescence Anisotropy-Application to Nonsense Suppressor Screening and Mechanistic Studies.
Mikel D Ghelfi, Saleem Y Bhat, Hong Li, Barry S Cooperman

Biomolecules· January 2023

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Ataluren binds to multiple protein synthesis apparatus sites and competitively inhibits release factor-dependent termination.
Shijie Huang, Arpan Bhattacharya, Mikel D Ghelfi, Hong Li, Clark Fritsch, Barry S Cooperman

Nat Commun· May 2022

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Site-Specific Fluorescent Labeling of RNA Interior Positions.
Barry S Cooperman

Molecules· March 2021

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Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms.
Martin Y Ng, Hong Li, Mikel D Ghelfi, Yale E Goldman, Barry S Cooperman

Proc Natl Acad Sci U S A· January 2021

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Dynamics of intracellular stress-induced tRNA trafficking.
Rabin Dhakal, Chunyi Tong, Sean Anderson, Anna S Kashina, Barry Cooperman

Nucleic Acids Res· February 2019

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New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery.
Martin Y Ng, Haibo Zhang, Amy Weil, Vijay Singh, Ryan Jamiolkowski, Barry S Cooperman

ACS Med Chem Lett· December 2018

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Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots.
Bo Wu, Haibo Zhang, Ruirui Sun, Sijia Peng, Barry S Cooperman

Nucleic Acids Res· October 2018

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Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome.
Darius Kavaliauskas, Chunlai Chen, Wei Liu, Barry S Cooperman, Yale E Goldman

Nucleic Acids Res· September 2018

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E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form.
Jesper S Johansen, Darius Kavaliauskas, Shawn H Pfeil, Mickaël Blaise, Barry S Cooperman

Nucleic Acids Res· September 2018

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tRNA Fluctuations Observed on Stalled Ribosomes Are Suppressed during Ongoing Protein Synthesis.
Ryan M Jamiolkowski, Chunlai Chen, Barry S Cooperman, Yale E Goldman

Biophys J· December 2017

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Probing the interaction between NatA and the ribosome for co-translational protein acetylation.
Robert S Magin, Sunbin Deng, Haibo Zhang, Barry Cooperman, Ronen Marmorstein

PLoS One· October 2017

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The kinetic mechanism of bacterial ribosome recycling.
Yuanwei Chen, Akira Kaji, Hideko Kaji, Barry S Cooperman

Nucleic Acids Res· September 2017

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Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position.
Wei Liu, Dongwon Shin, Martin Ng, Karissa Y Sanbonmatsu, Yitzhak Tor, Barry S Cooperman

Molecules· August 2017

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In vivo single-RNA tracking shows that most tRNA diffuses freely in live bacteria.
Anne Plochowietz, Ian Farrell, Zeev Smilansky, Barry S Cooperman, Achillefs N Kapanidis

Nucleic Acids Res· January 2017

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Elongation factor G initiates translocation through a power stroke.
Chunlai Chen, Xiaonan Cui, John F Beausang, Haibo Zhang, Ian Farrell, Barry S Cooperman

Proc Natl Acad Sci U S A· July 2016

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Kinetics of initiating polypeptide elongation in an IRES-dependent system.
Haibo Zhang, Martin Y Ng, Yuanwei Chen, Barry S Cooperman

Elife· June 2016

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