Publications by authors named "Barry M Forman"

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Discovery of novel modulators for the PPARα (peroxisome proliferator activated receptor α): Potential therapies for nonalcoholic fatty liver disease.
Donna D Yu, Gregg Van Citters, Hongzhi Li, Brian M Stoltz, Barry M Forman

Bioorg Med Chem· July 2021

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Identification of novel inverse agonists of estrogen-related receptors ERRγ and ERRβ.
Donna D Yu, Janice M Huss, Hongzhi Li, Barry M Forman

Bioorg Med Chem· March 2017

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Novel FXR (farnesoid X receptor) modulators: Potential therapies for cholesterol gallstone disease.
Donna D Yu, Sreenath S Andrali, Hongzhi Li, Min Lin, Wendong Huang, Barry M Forman

Bioorg Med Chem· September 2016

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Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled bile acid receptor 1 (GP-BAR1, TGR5) agonists.
Donna D Yu, Kyle M Sousa, Daniell L Mattern, Jeffrey Wagner, Xianghui Fu, Barry M Forman

Bioorg Med Chem· April 2015

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Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor.
Donna D Yu, Wenwei Lin, Barry M Forman, Taosheng Chen

Bioorg Med Chem· June 2014

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Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery.
Donna D Yu, Wenwei Lin, Taosheng Chen, Barry M Forman

Bioorg Med Chem· July 2013

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Bioimaging real-time PXR-dependent mdr1a gene regulation in mdr1a.fLUC reporter mice.
Long Gu, Jasmine Chen, Timothy W Synold, Barry M Forman, Susan E Kane

J Pharmacol Exp Ther· June 2013

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Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis.
Wei-Dong Chen, Donna Yu, Barry M Forman, Wendong Huang, Yan-Dong Wang

Hepatology· February 2013

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Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice.
Lisheng Zhang, Yan-Dong Wang, Wei-Dong Chen, Xichun Wang, Guiyu Lou, Barry M Forman

Hepatology· December 2012

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An improved synthesis of 6α-ethylchenodeoxycholic acid (6ECDCA), a potent and selective agonist for the Farnesoid X Receptor (FXR).
Donna Yu, Daniell L Mattern, Barry M Forman

Steroids· November 2012

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Specific bile acids inhibit hepatic fatty acid uptake in mice.
Biao Nie, Hyo Min Park, Melissa Kazantzis, Min Lin, Amy Henkin, Barry M Forman

Hepatology· October 2012

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Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression.
Nian Liu, Zhipeng Meng, Guiyu Lou, Weiping Zhou, Xiaoqiong Wang, Barry M Forman

Mol Endocrinol· May 2012

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FXR protects lung from lipopolysaccharide-induced acute injury.
Lisheng Zhang, Tao Li, Donna Yu, Barry M Forman, Wendong Huang

Mol Endocrinol· January 2012

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Insufficient bile acid signaling impairs liver repair in CYP27(-/-) mice.
Zhipeng Meng, Nian Liu, Xianghui Fu, Xiaoqiong Wang, Yan-Dong Wang, Barry M Forman

J Hepatol· October 2011

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The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice.
Yan-Dong Wang, Wei-Dong Chen, Donna Yu, Barry M Forman, Wendong Huang

Hepatology· October 2011

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FXR regulates liver repair after CCl4-induced toxic injury.
Zhipeng Meng, Yandong Wang, Lin Wang, Wen Jin, Nian Liu, Barry M Forman

Mol Endocrinol· May 2010

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Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription.
Wei-Dong Chen, Yan-Dong Wang, Lisheng Zhang, Steven Shiah, Meihua Wang, Barry M Forman

Hepatology· March 2010

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Identification of an endogenous ligand bound to a native orphan nuclear receptor.
Xiaohui Yuan, Tuong Chi Ta, Min Lin, Jane R Evans, Yinchen Dong, Barry M Forman

PLoS One· August 2009

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Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response.
Yan-Dong Wang, Wei-Dong Chen, Meihua Wang, Donna Yu, Barry M Forman

Hepatology· November 2008

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Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo.
Yan-Dong Wang, Fan Yang, Wei-Dong Chen, Xiongfei Huang, Lily Lai, Barry M Forman

Mol Endocrinol· July 2008

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Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation.
Changcheng Zhou, Michelle M Tabb, Edward L Nelson, Felix Grün, Suman Verma, Barry M Forman

J Clin Invest· August 2006

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Detection of designer steroids.
Xiaohui Yuan, Barry Marc Forman

Nucl Recept Signal· May 2006

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Linking lipids, Alzheimer's and LXRs?
Nilay V Patel, Barry Marc Forman

Nucl Recept Signal· May 2006

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Are those phospholipids in your pocket?
Barry Marc Forman

Cell Metab· March 2005

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Crystallographic analysis of murine constitutive androstane receptor ligand-binding domain complexed with 5alpha-androst-16-en-3alpha-ol.
Jeremy Vincent, Li Shan, Ming Fan, Joseph S Brunzelle, Barry M Forman

Acta Crystallogr Sect F Struct Biol Cryst Commun· January 2005

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