Publications by authors named "Barry Potter"

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A minimum catalytic unit for synthesis of InsP6 and 5-PP-InsP5 in Arabidopsis.
Hayley L Whitfield, Colleen Sprigg, Andrew M Riley, Barry V L Potter, Hui-Fen Kuo

Biochem J· December 2025

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Phosphorus-specific, liquid chromatography inductively coupled plasma mass spectrometry for analysis of inositol phosphate and inositol pyrophosphate metabolism.
Colleen Sprigg, Hayley L Whitfield, Philip T Leftwich, Hui-Fen Kuo, Tzyy-Jen Chiou, Barry V L Potter

Biochem J· November 2025

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Protective potential of Irosustat, STX140 and the sulfonate derivative 1G in counteracting cisplatin-induced renal and hepatic toxicities: An in vivo comparative study.
Hanan S Anbar, Aseel W Radi, Haidi A Shaker, Lama F Janoudi, Haya N Alsheikh Zain, Barry V L Potter

Life Sci· October 2025

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Exploring the role of estrogens and steroid sulfatase inhibition in platinum resistance, proliferation, migration, and cell death in high-grade serous ovarian cancer cells.
Nika Marolt, Barry V L Potter, Tea Lanišnik Rižner

Biomed Pharmacother· August 2025

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Analysis of Inositol Phosphates, Diphosphoinositol Phosphates, and Their Analogs by HPLC on an Acid-Compatible Stationary Phase with Detection by Complexation with Ferric Ion.
Hayley L Whitfield, Colleen Sprigg, Andrew M Riley, Megan L Shipton, Barry V L Potter

Methods Mol Biol· August 2025

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Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I.
Xiaoqi Liu, Zixuan Zhang, Tim Aguirre, Megan L Shipton, Lin Fu, Barry V L Potter

Metabolism· February 2025

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Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia-reperfusion injury by elevating plasma adiponectin.
Lin Fu, Jimin Du, David Furkert, Megan L Shipton, Xiaoqi Liu, Barry V L Potter

Cardiovasc Res· July 2024

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Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents.
Seyed-Omar Zaraei, Wolfgang Dohle, Hanan S Anbar, Randa El-Gamal, Bertrand Leblond, Barry V L Potter

Bioorg Med Chem· March 2024

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Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.
María Ángeles Márquez-Moñino, Raquel Ortega-García, Hayley Whitfield, Andrew M Riley, Lourdes Infantes, Barry V L Potter

Nat Commun· February 2024

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Crystal Structure and Enzymology of Inositol Tris/Tetrakisphosphate Kinase 1 (ITPK1).
Hayley L Whitfield, Raquel Faba Rodriguez, Megan L Shipton, Arthur W H Li, Andrew M Riley, Barry V L Potter

Biochemistry· January 2024

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Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs.
Sarah Hostachy, Huanchen Wang, Guangning Zong, Katy Franke, Andrew M Riley, Barry V L Potter

Chemistry· December 2023

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Promising drug candidates for the treatment of polycystic ovary syndrome (PCOS) as alternatives to the classical medication metformin.
Hanan S Anbar, Nisha Yarifbhai Vahora, Hajra Laghman Shah, Mariyam Mohammed Azam, Tamanna Islam, Barry V L Potter

Eur J Pharmacol· December 2023

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2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
Leon Hosang, Anke Löhndorf, Wolfgang Dohle, Anette Rosche, Stephen Marry, Barry V L Potter

Biochim Biophys Acta Mol Cell Res· August 2023

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2-Methoxyestradiol-3,17-,-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells.
Ylana Adami Franco, Manoel Oliveira de Moraes, Larissa A C Carvalho, Wolfgang Dohle, Renaira Oliveira da Silva, Barry V L Potter

Int J Mol Sci· July 2023

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Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein.
Mariana Sacerdoti, Lissy Z F Gross, Andrew M Riley, Karin Zehnder, Abhijeet Ghode, Barry V L Potter

Sci Signal· June 2023

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Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling.
Ji Qi, Weiwei Cheng, Zhe Gao, Yuanyuan Chen, Megan L Shipton, Barry V L Potter

Biomed Pharmacother· May 2023

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Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP.
Megan L Shipton, Fathima A Jamion, Simon Wheeler, Andrew M Riley, Felix Plasser, Barry V L Potter

Chem Sci· May 2023

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Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4.
Hayley L Whitfield, Sining He, Yinghong Gu, Colleen Sprigg, Hui-Fen Kuo, Barry V L Potter

Biochem J· March 2023

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Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations.
Ruqaiyyah Siddiqui, Mutasem Rawas-Qalaji, Mohammed I El-Gamal, Sreedevi Sajeev, Jayalakshmi Jagal, Barry V L Potter

Antibiotics (Basel)· March 2023

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2-Difluoromethoxy-Substituted Estratriene Sulfamates: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Steroid Sulfatase Inhibition.
Wolfgang Dohle, Hannah Asiki, Wojciech Gruchot, Paul A Foster, Havreen K Sahota, Barry V L Potter

ChemMedChem· December 2022

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Synthesis and In Vitro Antimicrobial SAR of Benzyl and Phenyl Guanidine and Aminoguanidine Hydrazone Derivatives.
Wolfgang Dohle, Xiangdong Su, Yamni Nigam, Edward Dudley, Barry V L Potter

Molecules· December 2022

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Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451.
Scott D Hargrave, Anna M Joubert, Barry V L Potter, Wolfgang Dohle, Sumari Marais

Molecules· June 2022

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A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Huanchen Wang, Lalith Perera, Nikolaus Jork, Guangning Zong, Andrew M Riley, Barry V L Potter

Nat Commun· April 2022

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Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-1-inosine 5'-monophosphate, Analogues and Early Structure-Activity Relationship.
Joanna M Watt, Richard Graeff, Barry V L Potter

Molecules· November 2021

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Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3.
Nigel Vicker, Helen V Bailey, Joanna M Day, Mary F Mahon, Andrew Smith, Barry V L Potter

Molecules· November 2021

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