Publications by authors named "Barry R Keith"

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Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors.
Kirk L Stevens, Krystal J Alligood, Jennifer G Badiang Alberti, Thomas R Caferro, Stanley D Chamberlain, Barry R Keith

Bioorg Med Chem Lett· January 2009

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells.
Gottfried E Konecny, Mark D Pegram, Natarajan Venkatesan, Richard Finn, Guorong Yang, Barry R Keith

Cancer Res· February 2006

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Discovery and biological evaluation of potent dual ErbB-2/EGFR tyrosine kinase inhibitors: 6-thiazolylquinazolines.
Micheal D Gaul, Yu Guo, Karen Affleck, G Stuart Cockerill, Tona M Gilmer, Barry R Keith

Bioorg Med Chem Lett· February 2003

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Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways.
Wenle Xia, Robert J Mullin, Barry R Keith, Lei-Hua Liu, Hong Ma

Oncogene· September 2002

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