Publications by authors named "Bart Roman"

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HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.
Céline Van Dender, Steven Timmermans, Maxime Roes, Madeleine Hellemans, Elise Moens, Bart Roman

Front Immunol· September 2025

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A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.
Céline Van Dender, Steven Timmermans, Ville Paakinaho, Tineke Vanderhaeghen, Jolien Vandewalle, Bart Roman

EMBO Mol Med· October 2024

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Glioblastoma-Associated Mesenchymal Stem/Stromal Cells and Cancer-Associated Fibroblasts: Partners in Crime?
Thibault Lootens, Bart I Roman, Christian V Stevens, Olivier De Wever, Robrecht Raedt

Int J Mol Sci· February 2024

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Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells.
Aranit Harizaj, Benedicte Descamps, Christophe Mangodt, Stephan Stremersch, Arianna Stoppa, Bart Roman

Biomater Sci· June 2021

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The Expanding Role of Chemistry in Optimizing Proteins for Human Health Applications.
Bart I Roman

J Med Chem· June 2021

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Essay: Avoiding unfounded health claims on small molecules in scientific literature.
Bart I Roman

Bioorg Chem· May 2019

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Medicinal Chemistry and Use of Myosin II Inhibitor ( S)-Blebbistatin and Its Derivatives.
Bart I Roman, Sigrid Verhasselt, Christian V Stevens

J Med Chem· November 2018

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Atom- and Mass-economical Continuous Flow Production of 3-Chloropropionyl Chloride and its Subsequent Amidation.
Marine Movsisyan, Thomas S A Heugebaert, Bart I Roman, Rudolf Dams, Rudy Van Campenhout

Chemistry· August 2018

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Synthesis of C-ring-modified blebbistatin derivatives and evaluation of their myosin II ATPase inhibitory potency.
Bart I Roman, Sigrid Verhasselt, Christophe W Mangodt, Olivier De Wever, Christian V Stevens

Bioorg Med Chem Lett· July 2018

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Recovering Actives in Multi-Antitarget and Target Design of Analogs of the Myosin II Inhibitor Blebbistatin.
Bart I Roman, Rita C Guedes, Christian V Stevens, Alfonso T García-Sosa

Front Chem· May 2018

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Vehicle development, pharmacokinetics and toxicity of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone in rodents.
Liselot M Mus, Geertrui Denecker, Frank Speleman, Bart I Roman

PLoS One· April 2018

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Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs.
Sigrid Verhasselt, Bart I Roman, Marc E Bracke, Christian V Stevens

Eur J Med Chem· August 2017

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Insights into the myosin II inhibitory potency of A-ring-modified (S)-blebbistatin analogs.
Sigrid Verhasselt, Christian V Stevens, Tom Van den Broecke, Marc E Bracke, Bart I Roman

Bioorg Med Chem Lett· July 2017

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Discovery of (S)-3'-hydroxyblebbistatin and (S)-3'-aminoblebbistatin: polar myosin II inhibitors with superior research tool properties.
Sigrid Verhasselt, Bart I Roman, Olivier De Wever, Kristof Van Hecke, Rik Van Deun

Org Biomol Chem· March 2017

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4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.
Bart I Roman, Tine De Ryck, Atanas Patronov, Svetoslav H Slavov, Barbara W A Vanhoecke

Eur J Med Chem· August 2015

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Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds.
Marc E Bracke, Bart I Roman, Christian V Stevens, Liselot M Mus, Virinder S Parmar

J Vis Exp· June 2015

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Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?
Tine De Ryck, Eline Vanlancker, Charlotte Grootaert, Bart I Roman, Laurens M De Coen

AMB Express· May 2015

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Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids.
Bart I Roman, Tine De Ryck, Sigrid Verhasselt, Marc E Bracke, Christian V Stevens

Bioorg Med Chem Lett· March 2015

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Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes.
Bart I Roman, Laurens M De Coen, Séverine Thérèse F C Mortier, Tine De Ryck, Barbara W A Vanhoecke

Bioorg Med Chem· September 2013

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Continuous synthesis of peralkylated imidazoles and their transformation into ionic liquids with improved (electro)chemical stabilities.
Cedric Maton, Nils De Vos, Bart I Roman, Evert Vanecht, Neil R Brooks

Chemphyschem· September 2012

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Synthesis of isoindoles and related iso-condensed heteroaromatic pyrroles.
Thomas S A Heugebaert, Bart I Roman, Christian V Stevens

Chem Soc Rev· September 2012

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Exploration of the SAR of anti-invasive chalcones: synthesis and biological evaluation of conformationally restricted analogues.
Bart I Roman, Tine De Ryck, Laura Dierickx, Barbara W A Vanhoecke, Alan R Katritzky

Bioorg Med Chem· August 2012

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Transglucosylation potential of six sucrose phosphorylases toward different classes of acceptors.
Dirk Aerts, Tom F Verhaeghe, Bart I Roman, Christian V Stevens, Tom Desmet

Carbohydr Res· September 2011

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Synthesis of β-, γ-, δ-, ..., ω-halogenated ketones and aldehydes.
Bart I Roman, Norbert De Kimpe, Christian V Stevens

Chem Rev· October 2010

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Experimental and computational study of the ring opening of tricyclic oxanorbornenes to polyhydro isoindole phosphonates.
Diederica D Claeys, Christian V Stevens, Bart I Roman, Pieter Van De Caveye, Michel Waroquier

Org Biomol Chem· August 2010

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