Publications by authors named "Bassem Refaat"

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Polydatin Mitigates Lead-Induced Nephropathy by Modulating Oxidative Stress, Inflammation, and the AMPK/AKT/Nrf2 Pathway in Rats.
Naief Dahran, Mohammad A Alobaidy, Wejdan H Owaydhah, Ehdaa K A Soubahi, Alaa A Eisa, Bassem Refaat

Biol Trace Elem Res· October 2025

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Doxorubicin-sanguinarine nanoparticles: formulation and evaluation of breast cancer cell apoptosis and cell cycle.
Mahmoud Zaki El-Readi, Majed Abdurhman Abdulkarim, Ahmed A H Abdellatif, Mohamed E Elzubeir, Bassem Refaat

Drug Dev Ind Pharm· September 2025

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Protective effects of oral pharmaceutical solution of fucoxanthin against paracetamol-induced liver injury: modulation of drug-metabolizing enzymes, oxidative stress, and apoptotic pathways in rats.
Safaa Y Eid, Maimonah F Koshak, Mohamed E Elzubier, Bassem Refaat, Riyad A Almaimani

Drug Dev Ind Pharm· April 2025

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Increased protein expression of interleukin-10 and its signalling molecules in colon cancer progression: potential prognostic and therapeutic targets.
Akhmed Aslam, Bassem Refaat, Riyad A Almaimani, Ahmad A Obaid, Abdulrahman Mujalli

Discov Oncol· April 2025

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Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation.
Akhmed Aslam, Faisal Minshawi, Hussain Almasmoum, Riyad Almaimani, Aiman Alsaegh, Bassem Refaat

J Egypt Natl Canc Inst· March 2025

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IL-10-Directed Cancer Immunotherapy: Preclinical Advances, Clinical Insights, and Future Perspectives.
Adel G El-Shemi, Afnan Alqurashi, Jihan Abdullah Abdulrahman, Hanin Dhaifallah Alzahrani, Khawlah Saad Almwalad, Bassem Refaat

Cancers (Basel)· March 2025

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Enhanced hepatoprotective effects of empagliflozin and vitamin D dual therapy against metabolic dysfunction-associated steatohepatitis in mice by boosted modulation of metabolic, oxidative stress, and inflammatory pathways.
Wesam F Farrash, Shakir Idris, Mohamed E Elzubier, Elshiekh B A Khidir, Akhmed Aslam, Bassem Refaat

Int J Exp Pathol· December 2024

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Cytotoxic activity, selectivity, and clonogenicity of fruits and resins of Saudi medicinal plants against human liver adenocarcinoma.
Ali Hendi Alghamdi, Aimun A E Ahmed, Mahadi Bashir, Haidar Abdalgadir, Asaad Khalid, Bassem Refaat

Drug Target Insights· October 2024

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Seroprevalence of transfusion-transmitted infections among blood donors in Makkah, Saudi Arabia.
Faisal Minshawi, Asim A Abdulshakoor, Emran M Alwakil, Ghaiyda T Basfar, Saeed Kabrah, Bassem Refaat

J Infect Dev Ctries· June 2024

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In-vitro Cytotoxicity Investigations for Phytoconstituents of Saudi Medicinal Plants With Putative Ocular Effects.
Ali Hendi Alghamdi, Aimun A E Ahmed, Haidar Abdalgadir, Mahadi Bashir, Asaad Khalid, Bassem Refaat

Integr Cancer Ther· May 2024

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Metformin and thymoquinone co-treatment enhance 5-fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
Wesam F Farrash, Akhmed Aslam, Riyad Almaimani, Faisal Minshawi, Hussain Almasmoum, Bassem Refaat

Biofactors· December 2023

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Improved Glycaemic Control and Nephroprotective Effects of Empagliflozin and Paricalcitol Co-Therapy in Mice with Type 2 Diabetes Mellitus.
Abdulrahman Mujalli, Wesam F Farrash, Ahmad A Obaid, Anmar A Khan, Riyad A Almaimani, Bassem Refaat

Int J Mol Sci· December 2023

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Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats.
Maimonah Fuad Koshak, Mahmoud Zaki El-Readi, Mohamed Elzubier Elzubier, Bassem Refaat, Riyad Adnan Almaimani

Mar Drugs· November 2023

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Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat.
Ahmad A Obaid, Hussain Almasmoum, Riyad A Almaimani, Mohamed El-Boshy, Akhmed Aslam, Bassem Refaat

J Trace Elem Med Biol· September 2023

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The Quality of Blood Donation Services and Its Association with Blood Donors' Trust and Loyalty at Makkah Blood Donation Centers in Saudi Arabia: A Cross-Sectional Study.
Saeed M Kabrah, Samer Abuzerr, Ruba Omar Almaghrabi, Raed Alserihi, Raed I Felimban, Bassem Refaat

Healthcare (Basel)· July 2023

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Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness.
Bassem Refaat, Akhmed Aslam, Shakir Idris, Ahmed H Almalki, Mofareh Y Alkhaldi

Front Endocrinol (Lausanne)· May 2023

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Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway.
Doha Reda, Gehad E Elshopakey, Talat A Albukhari, Samah J Almehmadi, Bassem Refaat

Front Pharmacol· May 2023

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and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug's Metabolism, Toxicity, and Multidrug Transporters.
Mohammed Hasan Mukhtar, Mahmoud Zaki El-Readi, Mohamed E Elzubier, Sameer H Fatani, Bassem Refaat

Molecules· April 2023

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Hepatoprotective and Neuroprotective Effects of Naringenin against Lead-Induced Oxidative Stress, Inflammation, and Apoptosis in Rats.
Lubna A H Mansour, Gehad E Elshopakey, Fatma M Abdelhamid, Talat A Albukhari, Samah J Almehmadi, Bassem Refaat

Biomedicines· April 2023

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Patterns of acute poisoning for children during outbreak of Corona virus in Makkah region Saudi Arabia.
Bashayer Mohammed Althobaiti, Mahmoud Zaki El-Readi, Mohammad Althubiti, Yosra Zakariyya Alhindi, Abdullah R Alzahrani, Bassem Refaat

Front Pediatr· March 2023

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Insights from the molecular docking analysis of EGFR antagonists.
Mohammad Azhar Kamal, Hanadi M Baeissa, Israa J Hakeem, Reem S Alazragi, Mohannad S Hazzazi, Bassem Refaat

Bioinformation· March 2023

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Antioxidative and Anti-Inflammatory Protective Effects of -Caryophyllene against Amikacin-Induced Nephrotoxicity in Rat by Regulating the Nrf2/AMPK/AKT and NF-B/TGF-/KIM-1 Molecular Pathways.
Bodour S Rajab, Talat A Albukhari, Anmar A Khan, Bassem Refaat, Samah J Almehmadi

Oxid Med Cell Longev· December 2022

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Deferasirox and vitamin D co-therapy mitigates iron-induced renal injury by enhanced modulation of cellular anti-inflammatory, anti-oxidative stress, and iron regulatory pathways in rat.
Mazen M Ghaith, Mohamed El-Boshy, Hussain Almasmoum, Abdelghany H Abdelghany, Firas S Azzeh, Bassem Refaat

J Trace Elem Med Biol· December 2022

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Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males.
Amani A Mahbub, Akhmed Aslam, Mohamed E Elzubier, Mohamed El-Boshy, Abdelghany H Abdelghany, Bassem Refaat

Front Endocrinol (Lausanne)· October 2022

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Associations of Clinical Factors and Blood Groups With the Severity of COVID-19 Infection in Makkah City, Saudi Arabia.
Nashwa Shesha, Sami Melebari, Saad Alghamdi, Bassem Refaat, Hind Naffadi

Front Cell Infect Microbiol· July 2022

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