Publications by authors named "Bastian Opitz"

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Community-acquired pneumonia in diabetic patients is characterised by a distinct pathogen spectrum and enhanced inflammation: results from CAPNETZ, a prospective observational cohort study.
Belén Millet Pascual-Leone, Facundo Fiocca Vernengo, David Hillus, Charlotte Wernicke, Gopinath Krishnamoorthy, Bastian Opitz

Infection· October 2025

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Diabetes impairs IFNγ-dependent antibacterial defense in the lungs.
Facundo Fiocca Vernengo, Ivo Röwekamp, Léa Boillot, Sandra Caesar, Patrick Johann Dörner, Bastian Opitz

Mucosal Immunol· April 2025

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Semisynthetic Glycoconjugate Vaccine Lead against Serotype O2afg Induces Functional Antibodies and Reduces the Burden of Acute Pneumonia.
Dacheng Shen, Bruna M S Seco, Luiz Gustavo Teixeira Alves, Ling Yao, Maria Bräutigam, Bastian Opitz

J Am Chem Soc· December 2024

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Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure.
Natascha Drude, Kai Diederich, Claudia U Duerr, Nadine Haase, Christoph Harms, Bastian Opitz

J Vis Exp· December 2024

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Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Morgan Essex, Belén Millet Pascual-Leone, Ulrike Löber, Mathias Kuhring, Bowen Zhang, Bastian Opitz

NPJ Biofilms Microbiomes· August 2024

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IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota.
Ivo Röwekamp, Laura Maschirow, Anne Rabes, Facundo Fiocca Vernengo, Lutz Hamann, Bastian Opitz

Proc Natl Acad Sci U S A· May 2024

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Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Patrick J Dörner, Harithaa Anandakumar, Ivo Röwekamp, Facundo Fiocca Vernengo, Belén Millet Pascual-Leone, Bastian Opitz

Nat Commun· March 2024

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CLEC12A Binds to but Has No Impact on the Host's Antibacterial Response.
Ann-Brit Klatt, Christina Diersing, Juliane Lippmann, Sabine Mayer-Lambertz, Felix Stegmann, Bastian Opitz

Int J Mol Sci· February 2023

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Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study.
Tilman Lingscheid, Lena J Lippert, David Hillus, Tassilo Kruis, Charlotte Thibeault, Bastian Opitz

Infection· December 2022

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TBK1's Role in Bacterial Pneumonia: Perhaps More than Macrophages and IFNs.
Facundo Fiocca Vernengo, Bastian Opitz

Am J Respir Cell Mol Biol· June 2022

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Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension.
Christoph Tabeling, Carla R González Calera, Jasmin Lienau, Jakob Höppner, Thomas Tschernig, Bastian Opitz

Front Immunol· June 2022

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Triggered Exosomal Release of ADAM10 Mediates Proteolytic Cleavage in Trans.
Ahmad Aljohmani, Bastian Opitz, Markus Bischoff, Daniela Yildiz

Int J Mol Sci· January 2022

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Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing.
Bryan A Wee, Joana Alves, Diane S J Lindsay, Ann-Brit Klatt, Fiona A Sargison, Bastian Opitz

Nat Commun· December 2021

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The microbiota in pneumonia: From protection to predisposition.
Charlotte Thibeault, Norbert Suttorp, Bastian Opitz

Sci Transl Med· January 2021

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Platelets Restrict the Oxidative Burst in Phagocytes and Facilitate Primary Progressive Tuberculosis.
Lisa Scheuermann, Gang Pei, Teresa Domaszewska, Joanna Zyla, Dagmar Oberbeck-Müller, Bastian Opitz

Am J Respir Crit Care Med· September 2020

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Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19).
Florian Kurth, Maria Roennefarth, Charlotte Thibeault, Victor M Corman, Holger Müller-Redetzky, Bastian Opitz

Infection· August 2020

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Microbiota-Dependent Regulation of Antimicrobial Immunity in the Lung.
Laura Maschirow, Norbert Suttorp, Bastian Opitz

Am J Respir Cell Mol Biol· September 2019

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STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.
Lutz Hamann, Juan S Ruiz-Moreno, Malgorzata Szwed, Malgorzata Mossakowska, Linn Lundvall, Bastian Opitz

Gerontology· August 2019

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Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice.
Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Bastian Opitz

Crit Care· October 2018

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Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.
Oliver H Robak, Markus M Heimesaat, Andrey A Kruglov, Sandra Prepens, Justus Ninnemann, Bastian Opitz

J Clin Invest· August 2018

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Downregulation of Membrane Trafficking Proteins and Lactate Conditioning Determine Loss of Dendritic Cell Function in Lung Cancer.
Nicoletta Caronni, Francesca Simoncello, Francesca Stafetta, Corrado Guarnaccia, Juan Sebastian Ruiz-Moreno, Bastian Opitz

Cancer Res· April 2018

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Recognition of microbial viability via TLR8 drives T cell differentiation and vaccine responses.
Matteo Ugolini, Jenny Gerhard, Sanne Burkert, Kristoffer Jarlov Jensen, Philipp Georg, Bastian Opitz

Nat Immunol· April 2018

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The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans.
Juan Sebastian Ruiz-Moreno, Lutz Hamann, Lei Jin, Leif E Sander, Monika Puzianowska-Kuznicka, Bastian Opitz

Infect Immun· March 2018

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The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.
Juan S Ruiz-Moreno, Lutz Hamann, Javeed A Shah, Annelies Verbon, Frank P Mockenhaupt, Bastian Opitz

PLoS Pathog· January 2018

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Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia.
Kristina Dietert, Birgitt Gutbier, Sandra M Wienhold, Katrin Reppe, Xiaohui Jiang, Bastian Opitz

PLoS One· December 2017

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