Publications by authors named "Benet Pera"

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Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Juan Estévez-Gallego, Beatriz Álvarez-Bernad, Benet Pera, Christoph Wullschleger, Olivier Raes

Structure· January 2023

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Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.
Jessica J Field, Benet Pera, Juan Estévez Gallego, Enrique Calvo, Javier Rodríguez-Salarichs

J Nat Prod· March 2018

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Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway.
Benet Pera, Jan Krumsiek, Sarit E Assouline, Rossella Marullo, Jayeshkumar Patel

EBioMedicine· February 2018

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Corrigendum: THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors.
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M Fernando, Nicholas Kwiatkowski, Rossella Marullo, Benet Pera

Nat Commun· February 2017

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THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors.
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M Fernando, Nicholas Kwiatkowski, Rosella Marullo, Benet Pera

Nat Commun· January 2017

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Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients.
Benet Pera, Tiffany Tang, Rossella Marullo, Shao-Ning Yang, Haelee Ahn

Clin Epigenetics· December 2016

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BO-1055, a novel DNA cross-linking agent with remarkable low myelotoxicity shows potent activity in sarcoma models.
Srikanth R Ambati, Jae-Hung Shieh, Benet Pera, Eloisi Caldas Lopes, Anisha Chaudhry

Oncotarget· July 2016

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High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells.
Benet Pera, M Nieves Calvo-Vidal, Srikanth Ambati, Michel Jordi, Alissa Kahn

Cancer Lett· November 2015

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Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Ruth Matesanz, Chiara Trigili, Javier Rodríguez-Salarichs, Ilaria Zanardi, Benet Pera

Bioorg Med Chem· September 2014

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PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors.
Marta Martínez-Díez, María José Guillén-Navarro, Benet Pera, Benjamin Pierre Bouchet, Juan Fernando Martínez-Leal

Biochem Pharmacol· April 2014

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New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
Benet Pera, Isabel Barasoain, Areti Pantazopoulou, Angeles Canales, Ruth Matesanz

ACS Chem Biol· September 2013

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A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.
Claire Coderch, Yong Tang, Javier Klett, Shu-En Zhang, Yun-Tao Ma, Benet Pera

Org Biomol Chem· May 2013

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Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.
Andrea Milelli, Vincenzo Tumiatti, Marialuisa Micco, Michela Rosini, Guendalina Zuccari, Benet Pera

Eur J Med Chem· November 2012

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Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Jessica J Field, Benet Pera, Enrique Calvo, Angeles Canales, Didier Zurwerra

Chem Biol· June 2012

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Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site.
Enrique Calvo, Isabel Barasoain, Ruth Matesanz, Benet Pera, Emilio Camafeita

Biochemistry· January 2012

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Modulation of microtubule interprotofilament interactions by modified taxanes.
Ruth Matesanz, Javier Rodríguez-Salarichs, Benet Pera, Angeles Canales, José Manuel Andreu

Biophys J· December 2011

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Mechanism of action of the cytotoxic macrolides amphidinolide X and J.
Chiara Trigili, Benet Pera, Marion Barbazanges, Janine Cossy, Christophe Meyer

Chembiochem· May 2011

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Cpl-7, a lysozyme encoded by a pneumococcal bacteriophage with a novel cell wall-binding motif.
Noemí Bustamante, Nuria E Campillo, Ernesto García, Cristina Gallego, Benet Pera

J Biol Chem· October 2010

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Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.
Benet Pera, Mina Razzak, Chiara Trigili, Oriol Pineda, Angeles Canales

Chembiochem· August 2010

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The binding mode of side chain- and C3-modified epothilones to tubulin.
Máté Erdélyi, Armando Navarro-Vázquez, Bernhard Pfeiffer, Christian N Kuzniewski, Andrea Felser, Benet Pera

ChemMedChem· June 2010

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