Publications by authors named "Benjamin Clarke"

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Hypoxic stress is an early pathogenic event in human VCP-mutant ALS astrocytes.
Hannah D Franklin, Hamish Crerar, Nishita Parnandi, Michael Lattke, Stanislaw Majewski, Benjamin E Clarke

Stem Cell Reports· December 2025

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1-Deoxysphingolipids Require Very-Long-Chain Ceramide Synthesis to Induce ER Stress and Neurotoxicity.
Colleen Byrnes, Benjamin A Clarke, Hongling Zhu, Saurav Majumder, Mari Kono

bioRxiv· December 2025

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Astrocytic RNA editing regulates the host immune response to alpha-synuclein.
Karishma D'Sa, Minee L Choi, Aaron Z Wagen, Núria Setó-Salvia, Olga Kopach, Benjamin E Clarke

Sci Adv· April 2025

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Towards an integrated approach for understanding glia in Amyotrophic Lateral Sclerosis.
Stanislaw Majewski, Pierre Klein, Séverine Boillée, Benjamin E Clarke, Rickie Patani

Glia· March 2025

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Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB.
Benjamin E Clarke, Oliver J Ziff, Giulia Tyzack, Marija Petrić Howe, Yiran Wang

Mol Neurodegener· November 2024

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Implementing treat-to-target urate-lowering therapy during hospitalizations for gout flares.
Mark D Russell, Louise Ameyaw-Kyeremeh, Flora Dell'Accio, Heather Lapham, Natalie Head, Benjamin D Clarke

Rheumatology (Oxford)· August 2024

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Diagnosis of Acute Aortic Syndrome in the Emergency Department (DAShED) study: an observational cohort study of people attending the emergency department with symptoms consistent with acute aortic syndrome.
Rachel McLatchie, Matthew J Reed, Nicola Freeman, Richard A Parker, Sarah Wilson, Benjamin Clarke, Ellise Clarke

Emerg Med J· February 2024

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Human muscle and spinal activation in response to body weight loading.
Benjamin Clarke, Jannah Khalid Al-Hammdany, Irene Di Giulio

J Anat· May 2023

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Changing trends in ethnicity and academic performance: observational cohort data from a UK medical school.
Prokriti Mukherji, Maryam A Adas, Benjamin Clarke, James B Galloway, Thomas Mulvey

BMJ Open· December 2022

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Optimized Infliximab Induction Predicts Better Long-Term Clinical and Biomarker Outcomes Compared to Standard Induction Dosing.
Sally Lawrence, Farah Faytrouni, Rachel E Harris, Mike Irvine, Estefania Carrion, Benjamin Clarke

J Pediatr Gastroenterol Nutr· November 2022

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Hospitalizations for Acute Gout: Process Mapping the Inpatient Journey and Identifying Predictors of Admission.
Mark D Russell, Deepak Nagra, Benjamin D Clarke, Sathiyaa Balachandran, April Buazon

J Rheumatol· July 2022

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Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis.
Doaa M Taha, Benjamin E Clarke, Claire E Hall, Giulia E Tyzack, Oliver J Ziff

Brain· April 2022

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The role of astrocytes in prion-like mechanisms of neurodegeneration.
Phillip Smethurst, Hannah Franklin, Benjamin E Clarke, Katie Sidle, Rickie Patani

Brain· March 2022

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Enhanced Expression of TRAP1 Protects Mitochondrial Function in Motor Neurons under Conditions of Oxidative Stress.
Benjamin E Clarke, Bernadett Kalmar, Linda Greensmith

Int J Mol Sci· February 2022

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Proposed empiric antibiotic therapy for prosthetic joint infections: an analysis of the Prosthetic Joint Infection in Australia and New Zealand, Observational (PIANO) cohort.
Joshua S Davis, Sarah Metcalf, David L Paterson, James O Robinson, Benjamin Clarke

Intern Med J· February 2022

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Responses of ticks to immersion in hot bathing water: Effect of surface type, water temperature, and soap on tick motor control.
David J Schimpf, Matthew M Ewert, Victor K Lai, Benjamin L Clarke

PLoS One· January 2022

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Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states.
Oliver J Ziff, Benjamin E Clarke, Doaa M Taha, Hamish Crerar, Nicholas M Luscombe

Genome Res· January 2022

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Improving outcomes for patients hospitalized with gout: a systematic review.
Mark D Russell, Benjamin D Clarke, Edward Roddy, James B Galloway

Rheumatology (Oxford)· December 2021

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Secukinumab as a potential trigger of inflammatory bowel disease in ankylosing spondylitis or psoriatic arthritis patients.
Ioana A Onac, Benjamin D Clarke, Cristina Tacu, Mark Lloyd, Vijay Hajela

Rheumatology (Oxford)· November 2021

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A systematic review and network meta-analysis of the safety of early interventional treatments in rheumatoid arthritis.
Maryam A Adas, Victoria B Allen, Mark Yates, Katie Bechman, Benjamin D Clarke

Rheumatology (Oxford)· October 2021

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IL-6 inhibition in the treatment of COVID-19: A meta-analysis and meta-regression.
Emmanuel Tharmarajah, April Buazon, Vishit Patel, Jennifer R Hannah, Maryam Adas, Benjamin D Clarke

J Infect· May 2021

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The safety of JAK-1 inhibitors.
Benjamin Clarke, Mark Yates, Maryam Adas, Katie Bechman, James Galloway

Rheumatology (Oxford)· May 2021

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Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 Mice.
Rebecca San Gil, Benjamin E Clarke, Heath Ecroyd, Bernadett Kalmar, Linda Greensmith

Cells· May 2021

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Reactive astrocytes in ALS display diminished intron retention.
Oliver J Ziff, Doaa M Taha, Hamish Crerar, Benjamin E Clarke, Anob M Chakrabarti

Nucleic Acids Res· April 2021

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The Interplay of RNA Binding Proteins, Oxidative Stress and Mitochondrial Dysfunction in ALS.
Jasmine Harley, Benjamin E Clarke, Rickie Patani

Antioxidants (Basel)· April 2021

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