Publications by authors named "Benjamin D Hopkins"

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Effect of TGF-β mediated phenotypic changes on prostate cancer cell anoikis response.
Prerna R Nepali, Edgar Gonzalez-Kozlova, Maitri Anegondi, Navneet Dogra, Maddison Archer, Benjamin D Hopkins

Oncogene· December 2025

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Multi-node inhibition targeting mTORC1, mTORC2 and PI3Kα potently inhibits the PI3K/AKT/mTOR pathway in endometrial and breast cancer models.
Petros A Tyrakis, Domen Kampjut, Georgina F Steele, H Jonathan G Lindström, Deborah Chirnomas, Benjamin D Hopkins

Br J Cancer· August 2025

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Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.
Shalini Nath, Sally Claridge, Genesis Lara Granados, Majd Al Assaad, Eric Park, Benjamin D Hopkins

Cell Rep Med· July 2025

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The role of biomarkers in the management of HPV-related oropharyngeal cancer.
Benjamin D Hopkins, James E Bates

Curr Opin Oncol· May 2025

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Epigenomic analysis identifies DTP subpopulation using HOPX to develop targeted therapy resistance in lung adenocarcinoma.
Yang Tian, Reshmee Bhattacharya, Seungyeul Yoo, Feng Jiang, Eric Park, Benjamin D Hopkins

iScience· May 2025

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Risk of late radiation necrosis more than 5 years after stereotactic radiosurgery.
Neal S McCall, Annabel Lu, Benjamin D Hopkins, David Qian, Kimberly B Hoang

J Neurosurg· April 2025

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Characteristics, Treatment, and Outcomes of Primary Urethral Cancer: A Multicenter Review Over Two Decades.
Benjamin D Hopkins, David C Qian, Karen M Xu, Ashley McCook-Veal, Jeffrey Switchenko

Clin Genitourin Cancer· February 2025

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Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.
Sally E Claridge, Shalini Nath, Anneliese Baum, Richard Farias, Julie-Ann Cavallo, Benjamin D Hopkins

Clin Transl Med· February 2025

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Epinephrine inhibits PI3Kα via the Hippo kinases.
Ting-Yu Lin, Shakti Ramsamooj, Tiffany Perrier, Katarina Liberatore, Louise Lantier, Benjamin D Hopkins

Cell Rep· December 2023

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Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in .
Priya Bhardwaj, Neil M Iyengar, Heba Zahid, Katharine M Carter, Dong Jun Byun, Benjamin D Hopkins

Sci Transl Med· February 2023

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An atlas of substrate specificities for the human serine/threonine kinome.
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Benjamin D Hopkins

Nature· January 2023

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Occipital Headache Evaluation and Rates of Migraine Assessment, Diagnosis, and Treatment in Patients Receiving Greater Occipital Nerve Blocks in an Academic Pain Clinic.
Shawn M Love, Benjamin D Hopkins, Christopher W Migdal, Nathaniel M Schuster

Pain Med· October 2022

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PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Christian C Dibble, Samuel A Barritt, Grace E Perry, Evan C Lien, Renee C Geck, Benjamin D Hopkins

Nature· August 2022

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PI3King the Environment for Growth: PI3K Activation Drives Transcriptome Changes That Support Oncogenic Growth.
Sally E Claridge, Benjamin D Hopkins

Cancer Res· June 2022

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Circling back to PTEN: Fumarate inhibits canonical tumor suppressor.
Sally E Claridge, Benjamin D Hopkins

Mol Cell· April 2022

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Patient-Derived In Vitro and In Vivo Models of Cancer.
Sally E Claridge, Julie-Ann Cavallo, Benjamin D Hopkins

Adv Exp Med Biol· March 2022

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A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients.
Chantal Pauli, Lamberto De Boni, Jonathan E Pauwels, Yanjiang Chen, Lara Planas-Paz, Benjamin D Hopkins

Mol Cancer Res· February 2022

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Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
Kenneth Wu, Khoi Q Huynh, Iris Lu, Moses Moustakim, Haibin Miao, Benjamin D Hopkins

Proc Natl Acad Sci U S A· February 2021

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Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators.
Kenneth Wu, Benjamin D Hopkins, Roberto Sanchez, Robert J DeVita, Zhen-Qiang Pan

J Cell Signal· January 2021

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Obesity-associated Adipose Stromal Cells Promote Breast Cancer Invasion Through Direct Cell Contact and ECM Remodeling.
Lu Ling, Jeffrey A Mulligan, Yunxin Ouyang, Adrian A Shimpi, Rebecca M Williams, Benjamin D Hopkins

Adv Funct Mater· November 2020

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Precision Targeting of -Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing.
Xuyu Liu, Marcus J C Long, Benjamin D Hopkins, Chaosheng Luo, Lingxi Wang

ACS Cent Sci· June 2020

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Insulin-PI3K signalling: an evolutionarily insulated metabolic driver of cancer.
Benjamin D Hopkins, Marcus D Goncalves, Lewis C Cantley

Nat Rev Endocrinol· May 2020

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PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.
Diana G Wang, Marcia N Paddock, Mark R Lundquist, Janet Y Sun, Oksana Mashadova, Benjamin D Hopkins

Cell Rep· May 2019

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Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer.
Cindy Hodakoski, Benjamin D Hopkins, Guoan Zhang, Taojunfeng Su, Zhe Cheng

Cancers (Basel)· January 2019

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Phosphatidylinositol 3-Kinase, Growth Disorders, and Cancer.
Marcus D Goncalves, Benjamin D Hopkins, Lewis C Cantley

N Engl J Med· November 2018

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