Publications by authors named "Benjamin Draper"

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Erratum: End-to-end characterization of AAV manufacturing process using charge detection mass spectrometry.
Lohra M Young, Benjamin E Draper, Martin F Jarrold, Clifford A Froelich, Seyed Pouria Motevalian

Mol Ther Methods Clin Dev· December 2025

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End-to-end characterization of AAV manufacturing process using charge detection mass spectrometry.
Lohra M Young, Benjamin E Draper, Martin F Jarrold, Clifford A Froelich, Seyed Pouria Motevalian

Mol Ther Methods Clin Dev· December 2025

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Toward an all-in-one recombinant adeno-associated virus vector for functionally ablating the prion gene using CRISPR-Cas technology.
Claire Verkuyl, Ari Belotserkovsky, Thomas Zerbes, Declan Williams, Medha R Krishnan, Benjamin Draper

PLoS One· November 2025

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Charge Detection Mass Spectrometry Reveals Norovirus GII.4 Virus-like Particles Failure to Complete.
Lohra M Miller, Benjamin E Draper, Martin F Jarrold

J Am Soc Mass Spectrom· August 2025

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Insights into Adeno-Associated Virus Capsid Charge Heterogeneity.
Jiaqi Wu, Benjamin E Draper, Martin F Jarrold, Christopher D Heger

Anal Chem· August 2025

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Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function.
Marta Barisa, Henrike P Muller, Elisa Zappa, Rivani Shah, Juliane L Buhl, Benjamin Draper

Nat Commun· August 2025

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Coupling of Size Exclusion Chromatography to High Throughput Charge Detection Mass Spectrometry for the Analysis of Large Proteins and Virus-like Particles.
Raj A Parikh, Lohra M Miller, Benjamin E Draper, Lavelay Kizekai, Balasubrahmanyam Addepalli

Anal Chem· February 2025

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Complementary Nanoparticle Characterization by Resistive-Pulse Sensing, Electron Microscopy, and Charge Detection Mass Spectrometry.
Lohra M Miller, Tanner W Young, Yi Wang, Benjamin E Draper, Xingchen Ye

Anal Chem· September 2024

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Charge Detection Mass Spectrometry Reveals Favored Structures in the Assembly of Virus-Like Particles: Polymorphism in Norovirus GI.1.
Lohra M Miller, Benjamin E Draper, Joseph C-Y Wang, Martin F Jarrold

Anal Chem· August 2024

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Charge Detection Mass Spectrometry Enables Molecular Characterization of Nucleic Acid Nanoparticles.
Polycarp C Ofoegbu, Grant A Knappe, Anna Romanov, Benjamin E Draper, Mark Bathe

ACS Nano· August 2024

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Protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of brain tumors.
Benjamin Draper, Chantelle Bowers, Eleni Vassalou, Ailsa Greppi, John Anderson

STAR Protoc· June 2024

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Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages.
Taylor N Szyszka, Michael P Andreas, Felicia Lie, Lohra M Miller, Lachlan S R Adamson, Benjamin E Draper

Proc Natl Acad Sci U S A· May 2024

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Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.
Daniel Fowler, Marta Barisa, Alba Southern, Callum Nattress, Elizabeth Hawkins, Benjamin Draper

Sci Transl Med· May 2024

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Recombinant AAV genome size effect on viral vector production, purification, and thermostability.
Nermin Ibreljic, Benjamin E Draper, Carl W Lawton

Mol Ther Methods Clin Dev· March 2024

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A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR.
Junping Zhang, Dylan A Frabutt, Matthew Chrzanowski, Ning Li, Lohra M Miller, Benjamin E Draper

Mol Ther Methods Clin Dev· March 2024

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Multiple Ion Charge Extraction (MICE) for High-Throughput Charge Detection Mass Spectrometry.
Raj A Parikh, Benjamin E Draper, Martin F Jarrold

Anal Chem· February 2024

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Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages.
Taylor N Szyszka, Michael P Andreas, Felicia Lie, Lohra M Miller, Lachlan S R Adamson, Benjamin E Draper

bioRxiv· February 2024

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Quantitative analysis of preferential utilization of AAV ITR as the packaging terminal signal.
Xin Li, Lohra Mickelle Miller, Matthew Chrzanowski, Jiahe Tian, Martin F Jarrold, Benjamin Draper

Front Bioeng Biotechnol· December 2023

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Harnessing Nanomedicine to Potentiate the Chemo-Immunotherapeutic Effects of Doxorubicin and Alendronate Co-Encapsulated in Pegylated Liposomes.
Alberto Gabizon, Hilary Shmeeda, Benjamin Draper, Ana Parente-Pereira, John Maher

Pharmaceutics· November 2023

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Partial genome content within rAAVs impacts performance in a cell assay-dependent manner.
Bryan Troxell, Sarah L Jaslow, I-Wei Tsai, Chelsea Sullivan, Benjamin E Draper

Mol Ther Methods Clin Dev· September 2023

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Antibody Binding to Recombinant Adeno Associated Virus Monitored by Charge Detection Mass Spectrometry.
Ashley E Grande, Xin Li, Lohra M Miller, Junping Zhang, Benjamin E Draper

Anal Chem· July 2023

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Analysis of Megadalton-Sized DNA by Charge Detection Mass Spectrometry: Entropic Trapping and Shearing in Nanoelectrospray.
Lohra M Miller, Benjamin E Draper, Lauren F Barnes, Polycarp C Ofoegbu, Martin F Jarrold

Anal Chem· June 2023

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Analysis of AAV-Extracted DNA by Charge Detection Mass Spectrometry Reveals Genome Truncations.
Lauren F Barnes, Benjamin E Draper, Justin Kurian, Yu-Ting Chen, Tatiana Shapkina

Anal Chem· March 2023

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Analysis of thermally driven structural changes, genome release, disassembly, and aggregation of recombinant AAV by CDMS.
Lauren F Barnes, Benjamin E Draper, Martin F Jarrold

Mol Ther Methods Clin Dev· December 2022

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Generation of human parallel chimeric antigen receptor (pCAR) T cells to achieve synergistic T cell co-stimulation.
Daniel Larcombe-Young, Lynsey Whilding, David Marc Davies, Benjamin Draper, Natasha Bechman

STAR Protoc· June 2022

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