Publications by authors named "Benjamin Engelhardt"

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Semi-mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E Wolff

CPT Pharmacometrics Syst Pharmacol· March 2025

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Exposure-response relationships of venetoclax in combination with carfilzomib and dexamethasone in relapsed/refractory t(11;14) multiple myeloma patients.
Mohamed Ali Badawi, Benjamin Engelhardt, Edyta Dobkowska, Rong Deng, Jonathan L Kaufman

Invest New Drugs· December 2024

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Dosing of Venetoclax in Pediatric Patients with Relapsed Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships.
Mohamed Badawi, Sathej Gopalakrishnan, Benjamin Engelhardt, Tammy Palenski, Seth E Karol

Clin Ther· October 2024

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Venetoclax in biomarker-selected multiple myeloma patients: Impact of exposure on clinical efficacy and safety.
Mohamed Badawi, Sheryl Coppola, Doerthe Eckert, Sathej Gopalakrishnan, Benjamin Engelhardt

Hematol Oncol· January 2024

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Use of Clinical Trial Simulations to Compare the Performance of Different Approaches for Population Analyses of Pediatric Pharmacokinetic Data.
Zaid Temrikar, Elena Muensterman, Benjamin Engelhardt, Mohamed-Eslam F Mohamed

J Clin Pharmacol· July 2023

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Upadacitinib pharmacokinetics and exposure-response analyses of efficacy and safety in psoriatic arthritis patients - Analyses of phase III clinical trials.
Elena Muensterman, Benjamin Engelhardt, Sathej Gopalakrishnan, Jaclyn K Anderson, Mohamed-Eslam F Mohamed

Clin Transl Sci· January 2022

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SEEDS: data driven inference of structural model errors and unknown inputs for dynamic systems biology.
Tobias Newmiwaka, Benjamin Engelhardt, Philipp Wendland, Dominik Kahl, Holger Fröhlich

Bioinformatics· June 2021

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Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181).
John Powderly, Alexander Spira, Shunsuke Kondo, Toshihiko Doi, Jason J Luke, Benjamin Engelhardt

Clin Transl Sci· January 2021

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Modelling and mathematical analysis of the M$_{2}$ receptor-dependent joint signalling and secondary messenger network in CHO cells.
Benjamin Engelhardt, Janine Holze, Christina Elliott, George S Baillie, Maik Kschischo

Math Med Biol· September 2018

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A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models.
Benjamin Engelhardt, Maik Kschischo, Holger Fröhlich

J R Soc Interface· June 2017

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Learning (from) the errors of a systems biology model.
Benjamin Engelhardt, Holger Frőhlich, Maik Kschischo

Sci Rep· February 2016

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