Publications by authors named "Benjamin Hurrell"

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ICOS regulates IL-10 production in group 2 innate lymphoid cells via cholesterol and cortisol biosynthesis.
Yoshihiro Sakano, Kei Sakano, Benjamin P Hurrell, Mohammad H Kazemi, Xin Li

J Clin Invest· September 2025

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The Expanding Role of ILC2s in Allergic Airways Disease.
Jafar Cain, Benjamin Hurrell, Omid Akbari

Allergy· September 2025

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Targeting CD48 Ameliorates ILC2-mediated Airway Hyperreactivity by Disrupting the PKCβ Pathway.
Kei Sakano, Yoshihiro Sakano, Benjamin P Hurrell, Mohammad H Kazemi, Xin Li

Am J Respir Cell Mol Biol· July 2025

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BTLA agonist attenuates Th17-driven inflammation in a mouse model of steroid-resistant asthma.
Christine Quach, Xin Li, Pedram Shafiei-Jahani, Meng Li, Stephen Shen, Benjamin P Hurrell

Front Immunol· April 2025

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FOXO1 pathway activation by VISTA immune checkpoint restrains pulmonary ILC2 functions.
Mohammad Hossein Kazemi, Zahra Momeni-Varposhti, Xin Li, Benjamin P Hurrell, Yoshihiro Sakano

J Clin Invest· January 2025

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SIRPα engagement regulates ILC2 effector function and alleviates airway hyperreactivity via modulating energy metabolism.
Yoshihiro Sakano, Kei Sakano, Benjamin P Hurrell, Pedram Shafiei-Jahani, Mohammad Hossein Kazemi

Cell Mol Immunol· October 2024

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NLRP1-dependent activation of Gasdermin D in neutrophils controls cutaneous leishmaniasis.
Michiel Goris, Katiuska Passelli, Sanam Peyvandi, Miriam Díaz-Varela, Oaklyne Billion, Benjamin P Hurrell

PLoS Pathog· September 2024

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CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus.
Pedram Shafiei-Jahani, Shi Yan, Mohammad H Kazemi, Xin Li, Amitis Akbari, Benjamin P Hurrell

Cell Rep· July 2024

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Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivity.
Yoshihiro Sakano, Kei Sakano, Benjamin P Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani

J Allergy Clin Immunol· May 2024

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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity.
Benjamin P Hurrell, Stephen Shen, Xin Li, Yoshihiro Sakano, Mohammad Hossein Kazemi

J Exp Med· May 2024

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Iron controls the development of airway hyperreactivity by regulating ILC2 metabolism and effector function.
Benjamin P Hurrell, Yoshihiro Sakano, Stephen Shen, Doumet Georges Helou, Meng Li

Sci Transl Med· May 2024

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Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages.
Yumei Li, Christine Wu, Jiyoung Lee, Qiqi Ning, Juhyeon Lim, Benjamin P Hurrell

PLoS Pathog· March 2024

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LAIR-1 limits macrophage activation in acute inflammatory lung injury.
Doumet Georges Helou, Christine Quach, Benjamin P Hurrell, Xin Li, Meng Li

Mucosal Immunol· December 2023

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Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models.
Emily Howard, Benjamin P Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Spyridon Hasiakos

Nat Commun· September 2023

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Enhancing autophagy in CD11c antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome.
Christine Quach, Doumet Georges Helou, Meng Li, Benjamin Pierre Hurrell, Emily Howard

Cell Rep· August 2023

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Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells.
Doumet Georges Helou, Christine Quach, Marshall Fung, Jacob D Painter, Benjamin P Hurrell

J Allergy Clin Immunol· February 2023

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PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability.
Benjamin P Hurrell, Doumet Georges Helou, Emily Howard, Jacob D Painter, Pedram Shafiei-Jahani

Nat Commun· August 2022

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Cannabinoid receptor 2 engagement promotes group 2 innate lymphoid cell expansion and enhances airway hyperreactivity.
Benjamin P Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Emily Howard, Jacob D Painter

J Allergy Clin Immunol· May 2022

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Autophagy impairment in liver CD11c cells promotes non-alcoholic fatty liver disease through production of IL-23.
Lauriane Galle-Treger, Doumet Georges Helou, Christine Quach, Emily Howard, Benjamin P Hurrell

Nat Commun· March 2022

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LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity.
Doumet Georges Helou, Pedram Shafiei-Jahani, Benjamin P Hurrell, Jacob D Painter, Christine Quach

J Allergy Clin Immunol· January 2022

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PD-1 Blockade on Tumor Microenvironment-Resident ILC2s Promotes TNF-α Production and Restricts Progression of Metastatic Melanoma.
Emily Howard, Benjamin P Hurrell, Doumet Georges Helou, Christine Quach, Jacob D Painter

Front Immunol· December 2021

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CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation.
Pedram Shafiei-Jahani, Doumet Georges Helou, Benjamin P Hurrell, Lauriane Galle-Treger, Emily Howard

Mucosal Immunol· July 2021

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CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma.
Pedram Shafiei-Jahani, Doumet Georges Helou, Benjamin P Hurrell, Emily Howard, Christine Quach

Nat Commun· May 2021

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Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity.
Benjamin P Hurrell, Emily Howard, Lauriane Galle-Treger, Doumet Georges Helou, Pedram Shafiei-Jahani

Front Immunol· April 2021

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DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus.
Pedram Shafiei-Jahani, Benjamin P Hurrell, Lauriane Galle-Treger, Doumet Georges Helou, Emily Howard

Nat Commun· September 2020

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