Publications by authors named "Benjamin Kefas"

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A comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.
Myron K Gibert, Ying Zhang, Shekhar Saha, Guruprasad Varma Konduru, Pawel Marcinkiewicz, Benjamin Kefas

bioRxiv· July 2025

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T-type calcium channels regulate medulloblastoma and can be targeted for therapy.
Collin J Dube, Michelle Lai, Ying Zhang, Shekhar Saha, Ulas Yener, Benjamin Kefas

J Neurooncol· May 2025

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Discovery and therapeutic exploitation of Master Regulatory miRNAs in Glioblastoma.
Shekhar Saha, Ying Zhang, Myron K Gilbert, Collin Dube, Farina Hanif, Benjamin Kefas

bioRxiv· April 2025

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Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth.
Collin J Dube, Ying Zhang, Shekhar Saha, Michelle Lai, Myron K Gibert, Benjamin Kefas

bioRxiv· August 2024

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A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.
Myron K Gibert, Ying Zhang, Shekhar Saha, Pawel Marcinkiewicz, Collin Dube, Benjamin Kefas

Res Sq· April 2024

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miR-3174 Is a New Tumor Suppressor MicroRNA That Inhibits Several Tumor-Promoting Genes in Glioblastoma.
Farina Hanif, Ying Zhang, Collin Dube, Myron K Gibert, Shekhar Saha, Benjamin Kefas

Int J Mol Sci· May 2023

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Transcribed Ultraconserved Regions in Cancer.
Myron K Gibert, Aditya Sarkar, Bilhan Chagari, Christian Roig-Laboy, Shekhar Saha, Benjamin Kefas

Cells· May 2022

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Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.
Desiree Hunt Floyd, Ying Zhang, Bijan K Dey, Benjamin Kefas, Hannah Breit

PLoS One· January 2015

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microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.
Jungeun Kim, Ying Zhang, Michael Skalski, Josie Hayes, Benjamin Kefas

Cancer Res· March 2014

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A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival.
Benjamin Kefas, Desiree H Floyd, Laurey Comeau, Alyse Frisbee, Charli Dominguez

Neuro Oncol· December 2013

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Signal Transduction Pathways Mediated by Secreted and Non-secreted Forms of intact Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) and its 1-97 N-terminal Fragment in PC-3 Human Prostate Cancer Cells.
Hanief M Shahjee, Benjamin Kefas, Nisan Bhattacharyya, Mohamed K Radwan

J Cancer Ther· October 2013

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Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.
Charli L Dominguez, Desiree H Floyd, Aizhen Xiao, Garrett R Mullins, Benjamin A Kefas

Cancer Discov· July 2013

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Oncogenic effects of miR-10b in glioblastoma stem cells.
Fadila Guessous, Melissa Alvarado-Velez, Lukasz Marcinkiewicz, Ying Zhang, Jungeun Kim, Benjamin Kefas

J Neurooncol· April 2013

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Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.
Desiree H Floyd, Benjamin Kefas, Oleksandr Seleverstov, Olga Mykhaylyk, Charli Dominguez

Neuro Oncol· October 2012

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Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.
Jason E Duex, Laurey Comeau, Alexander Sorkin, Benjamin Purow, Benjamin Kefas

J Biol Chem· July 2011

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Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells.
Benjamin Kefas, Laurey Comeau, Nicholas Erdle, Emmitt Montgomery, Samson Amos

Neuro Oncol· November 2010

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Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors.
Lily Ng, Arkady Lyubarsky, Sergei S Nikonov, Michelle Ma, Maya Srinivas, Benjamin Kefas

J Neurosci· March 2010

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The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors.
Benjamin Kefas, Laurey Comeau, Desiree H Floyd, Oleksandr Seleverstov, Jakub Godlewski

J Neurosci· December 2009

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MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes.
Yunqing Li, Fadila Guessous, Ying Zhang, Charles Dipierro, Benjamin Kefas

Cancer Res· October 2009

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Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.
Ailing Lu, Lily Ng, Michelle Ma, Benjamin Kefas, Terry F Davies

Endocrinology· March 2009

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Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy.
Yunqing Li, Fadila Guessous, Charles DiPierro, Ying Zhang, Tucker Mudrick, Benjamin Kefas

Mol Cancer Ther· February 2009

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Notch-1 regulates transcription of the epidermal growth factor receptor through p53.
Benjamin W Purow, Tilak K Sundaresan, Michael J Burdick, Benjamin A Kefas, Laurey D Comeau

Carcinogenesis· May 2008

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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma.
Benjamin Kefas, Jakub Godlewski, Laurey Comeau, Yunqing Li, Roger Abounader

Cancer Res· May 2008

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Metformin-induced stimulation of AMP-activated protein kinase in beta-cells impairs their glucose responsiveness and can lead to apoptosis.
Benjamin A Kefas, Ying Cai, Karen Kerckhofs, Zhidong Ling, Geert Martens

Biochem Pharmacol· August 2004

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Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.
Mark Van de Casteele, Benjamin Ate Kefas, Ying Cai, Harry Heimberg, Donald K Scott

Biochem Biophys Res Commun· December 2003

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