Publications by authors named "Benjamin N Atkinson"

Claim this Profile
D
Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity.
Benjamin N Atkinson, Nicky J Willis, Yuguang Zhao, Chandni Patel, Sarah Frew

Eur J Med Chem· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1-1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step.
Benjamin N Atkinson, Nicky J Willis, Jennifer Smith, Rebecca Gill, Jody Ali

RSC Adv· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural Analysis and Development of Notum Fragment Screening Hits.
Yuguang Zhao, William Mahy, Nicky J Willis, Hannah L Woodward, David Steadman, Benjamin N Atkinson

ACS Chem Neurosci· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
Nicky J Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah L Woodward, Benjamin N Atkinson

J Med Chem· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.
David Steadman, Benjamin N Atkinson, Yuguang Zhao, Nicky J Willis, Sarah Frew

J Med Chem· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.
Elliott D Bayle, Fredrik Svensson, Benjamin N Atkinson, David Steadman, Nicky J Willis

J Med Chem· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.
William Mahy, Mikesh Patel, David Steadman, Hannah L Woodward, Benjamin N Atkinson

J Med Chem· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Controlling Engineered P2X Receptors with Light.
Benjamin N Atkinson, Vijay Chudasama, Liam E Browne

Methods Mol Biol· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.
Benjamin N Atkinson, David Steadman, William Mahy, Yuguang Zhao, James Sipthorp

Bioorg Med Chem Lett· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent.
Nicky J Willis, Elliott D Bayle, George Papageorgiou, David Steadman, Benjamin N Atkinson

Beilstein J Org Chem· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen.
Benjamin N Atkinson, David Steadman, Yuguang Zhao, James Sipthorp, Luca Vecchia

Medchemcomm· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives.
Benjamin N Atkinson, Hannah L Woodward, James Sipthorp, Paul V Fish

Org Biomol Chem· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transamidation of primary amides with amines catalyzed by zirconocene dichloride.
Benjamin N Atkinson, A Rosie Chhatwal, Helen V Lomax, James W Walton, Jonathan M J Williams

Chem Commun (Camb)· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transamidation of primary amides with amines using hydroxylamine hydrochloride as an inorganic catalyst.
C Liana Allen, Benjamin N Atkinson, Jonathan M J Williams

Angew Chem Int Ed Engl· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis