Publications by authors named "Benjamin Neel"

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Engineered antibodies that stabilize drug-modified KRAS neoantigens enable selective and potent cross-HLA immunotherapy.
Lorenzo Maso, Sarah A Mosure, Sergio A Rodriguez-Aponte, Angelina Pizzo, Diamond N Mensah, Benjamin G Neel

Nat Commun· December 2025

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Models of High-Grade Serous Ovarian Carcinoma.
Oscar J Pundel, Benjamin G Neel

Cold Spring Harb Perspect Med· October 2025

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Generation of actionable, cancer-specific neoantigens from KRAS(G12C) with adagrasib.
Lorenzo Maso, Epsa Rajak, Takamitsu Hattori, Zhengshan Hu, Akiko Koide, Benjamin G Neel

Proc Natl Acad Sci U S A· August 2025

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T lymphocyte-specific deletion of SHP1 and SHP2 promotes activation-induced cell death of CD4 T cells and impairs antitumor response.
Connor J R Foster, Jasper Du, Oscar Pundel, Mitchell J Geer, Ryan C Ripert, Benjamin G Neel

Proc Natl Acad Sci U S A· July 2025

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Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models.
Minkyung Kang, Jihye Choi, Jeongho Han, Toshiyuki Araki, Soo-Whee Kim, Benjamin G Neel

J Clin Invest· April 2025

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Characterization of tumour heterogeneity through segmentation-free representation learning on multiplexed imaging data.
Jimin Tan, Hortense Le, Jiehui Deng, Yingzhuo Liu, Yuan Hao, Benjamin G Neel

Nat Biomed Eng· March 2025

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A mechanism for hypoxia-induced inflammatory cell death in cancer.
Abhishek Bhardwaj, Maria C Panepinto, Beatrix Ueberheide, Benjamin G Neel

Nature· January 2025

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Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.
Sameer Farouk Sait, Kwan Ho Tang, Steven P Angus, Rebecca Brown, Daochun Sun, Benjamin G Neel

Proc Natl Acad Sci U S A· January 2025

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T Lymphocyte-Specific Deletion of SHP1 and SHP2 Promotes Activation-Induced Cell Death of CD4+ T Cells and Impairs Antitumor Response.
Connor J R Foster, Jasper Du, Oscar Pundel, Mitchell J Geer, Ryan C Ripert, Benjamin G Neel

bioRxiv· January 2025

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Characterization of tumor heterogeneity through segmentation-free representation learning.
Jimin Tan, Hortense Le, Jiehui Deng, Yingzhuo Liu, Yuan Hao, Benjamin G Neel

bioRxiv· September 2024

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Molecular basis for antibody recognition of multiple drug-peptide/MHC complexes.
Lorenzo Maso, Epsa Rajak, Injin Bang, Akiko Koide, Takamitsu Hattori, Benjamin G Neel

Proc Natl Acad Sci U S A· May 2024

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Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation.
Ryouhei Tsutsumi, Beatrix Ueberheide, Feng-Xia Liang, Benjamin G Neel, Ryuichi Sakai

Nat Commun· April 2024

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Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Xinyuan Tong, Ayushi S Patel, Eejung Kim, Hongjun Li, Yueqing Chen, Benjamin G Neel

Cancer Cell· March 2024

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Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
Suman Mukhopadhyay, Hsin-Yi Huang, Ziyan Lin, Michela Ranieri, Shuai Li, Benjamin G Neel

Cancer Res· December 2023

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Identification of a Novel Hypoxia-induced Inflammatory Cell Death Pathway.
Abhishek Bhardwaj, Maria Antonelli, Beatrix Ueberheide, Benjamin G Neel

bioRxiv· September 2023

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Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets.
Rui Sun, Weigang Ge, Yi Zhu, Azin Sayad, Augustin Luna, Benjamin G Neel

Mol Cell Proteomics· August 2023

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Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation.
Ryouhei Tsutsumi, Beatrix Ueberheide, Feng-Xia Liang, Benjamin G Neel, Ryuichi Sakai

bioRxiv· July 2023

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Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition.
Wei Wei, Mitchell J Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel

J Exp Med· May 2023

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metabolomics identifies CD38 as an emergent vulnerability in -mutant lung cancer.
Jiehui Deng, David H Peng, David Fenyo, Hao Yuan, Alfonso Lopez, Benjamin G Neel

bioRxiv· April 2023

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Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy.
Takamitsu Hattori, Lorenzo Maso, Kiyomi Y Araki, Akiko Koide, James Hayman, Benjamin G Neel

Cancer Discov· January 2023

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Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
John P Brabson, Tiffany Leesang, Yoon Sing Yap, Jingjing Wang, Minh Q Lam, Benjamin G Neel

Cell Rep· January 2023

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Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance.
Kim Loh, Atsushi Fukushima, Xinmei Zhang, Sandra Galic, Dana Briggs, Benjamin G Neel

Cell Metab· November 2022

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The current state of the art and future trends in RAS-targeted cancer therapies.
Salman R Punekar, Vamsidhar Velcheti, Benjamin G Neel, Kwok-Kin Wong

Nat Rev Clin Oncol· October 2022

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MMD-associated SNPs encode dominant-negative alleles that globally impair ubiquitylation.
Abhishek Bhardwaj, Robert S Banh, Wei Zhang, Sachdev S Sidhu, Benjamin G Neel

Life Sci Alliance· May 2022

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Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer.
Chewei Anderson Chang, Jayu Jen, Shaowen Jiang, Azin Sayad, Arvind Singh Mer, Benjamin G Neel

Cancer Discov· April 2022

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