Publications by authors named "Benjamin Uzan"

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DYRK1A inhibition restores pancreatic functions and improves glucose metabolism in a preclinical model of type 2 diabetes.
Romane Bertrand, Stefania Tolu, Delphine Picot, Cécile Tourrel-Cuzin, Ayoub Ouahab, Benjamin Uzan

Mol Metab· November 2025

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High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL.
Julien Calvo, Irina Naguibneva, Anthony Kypraios, Florian Gilain, Benjamin Uzan

Leukemia· February 2025

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The flavonoid resokaempferol improves insulin secretion from healthy and dysfunctional pancreatic β-cells.
Guillaume Gautheron, Sylvie Péraldi-Roux, Justine Vaillé, Sahla Belhadj, Andrzej Patyra, Benjamin Uzan

Br J Pharmacol· January 2025

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T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including hepatocyte growth factor.
Charly Le Maout, Lucine Fahy, Laurent Renou, Caroline Devanand, Charlotte Duwat, Benjamin Uzan

Biomed Pharmacother· August 2024

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Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy.
Etienne Delangre, Gaëlle Pommier, Stefania Tolu, Benjamin Uzan, Danielle Bailbé

Biomed Pharmacother· August 2023

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Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia.
Tra Ly Nguyen, Marie-Julie Nokin, Silvia Terés, Mercedes Tomé, Clément Bodineau, Benjamin Uzan

Mol Oncol· May 2021

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Ultra-high-dose-rate FLASH and Conventional-Dose-Rate Irradiation Differentially Affect Human Acute Lymphoblastic Leukemia and Normal Hematopoiesis.
Sara Chabi, Thi Hong Van To, Ron Leavitt, Sandrine Poglio, Patrik Gonçalves Jorge, Benjamin Uzan

Int J Radiat Oncol Biol Phys· March 2021

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Hypoxia favors chemoresistance in T-ALL through an HIF1α-mediated mTORC1 inhibition loop.
Lucine Fahy, Julien Calvo, Sara Chabi, Laurent Renou, Charly Le Maout, Benjamin Uzan

Blood Adv· January 2021

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Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.
Alexandre Fagnan, Frederik Otzen Bagger, Maria-Riera Piqué-Borràs, Cathy Ignacimouttou, Alexis Caulier, Benjamin Uzan

Blood· August 2020

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Desperately seeking a home marrow niche for T-cell acute lymphoblastic leukaemia.
Julien Calvo, Lucine Fahy, Benjamin Uzan, Françoise Pflumio

Adv Biol Regul· December 2019

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T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7.
Anne Buffière, Benjamin Uzan, Romain Aucagne, François Hermetet, Manon Mas

Oncogene· November 2019

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Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors.
Sara Chabi, Benjamin Uzan, Irina Naguibneva, Julien Rucci, Lucine Fahy

Cell Rep· November 2019

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Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia.
Diego Sánchez-Martínez, Matteo L Baroni, Francisco Gutierrez-Agüera, Heleia Roca-Ho, Oscar Blanch-Lombarte, Benjamin Uzan

Blood· May 2019

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Saracatinib impairs maintenance of human T-ALL by targeting the LCK tyrosine kinase in cells displaying high level of lipid rafts.
Anne Buffière, Théo Accogli, Laetitia Saint-Paul, Géraldine Lucchi, Benjamin Uzan

Leukemia· September 2018

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Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia.
Xavier Cahu, Julien Calvo, Sandrine Poglio, Nais Prade, Benoit Colsch, Benjamin Uzan

Blood Adv· September 2017

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Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia.
Laurent Renou, Pierre-Yves Boelle, Caroline Deswarte, Salvatore Spicuglia, Aissa Benyoucef, Benjamin Uzan

Blood Adv· May 2017

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A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche.
Pierre Charbord, Claire Pouget, Hans Binder, Florent Dumont, Grégoire Stik, Benjamin Uzan

Cell Stem Cell· September 2014

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Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.
Benjamin Uzan, Sandrine Poglio, Bastien Gerby, Ching-Lien Wu, Julia Gross

EMBO Mol Med· June 2014

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Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Li Pan, Richard W J Groen, Frederic Baleydier, Alex Kentsis, Benjamin Uzan

J Clin Invest· February 2014

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Adrenomedullin(22-52) combats inflammation and prevents systemic bone loss in murine collagen-induced arthritis.
Marie-Dominique Ah Kioon, Carine Asensio, Hang-Korng Ea, Frédéric Velard, Benjamin Uzan

Arthritis Rheum· April 2012

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Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation.
Marie-Dominique Ah Kioon, Carine Asensio, Hang-Korng Ea, Benjamin Uzan, Martine Cohen-Solal

Arthritis Res Ther· March 2011

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Neonatal growth and regeneration of beta-cells are regulated by the Wnt/beta-catenin signaling in normal and diabetic rats.
Florence Figeac, Benjamin Uzan, Monique Faro, Noura Chelali, Bernard Portha

Am J Physiol Endocrinol Metab· February 2010

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Mechanisms of KGF mediated signaling in pancreatic duct cell proliferation and differentiation.
Benjamin Uzan, Florence Figeac, Bernard Portha, Jamileh Movassat

PLoS One· May 2009

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Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway.
Benjamin Uzan, Aude Villemin, Jean-Michel Garel, Michèle Cressent

J Cell Physiol· April 2008

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A critical role for adrenomedullin-calcitonin receptor-like receptor in regulating rheumatoid fibroblast-like synoviocyte apoptosis.
Benjamin Uzan, Hang-Korng Ea, Jean-Marie Launay, Jean-Michel Garel, Romuald Champy

J Immunol· May 2006

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