Publications by authors named "Benoit Chabot"

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Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals.
Ali Zahedi Amiri, Choudhary Ahmed, Subha Dahal, Filomena Grosso, Haomin Leng, Benoit Chabot

Viruses· December 2024

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A defective splicing machinery promotes senescence through MDM4 alternative splicing.
Mathieu Deschênes, Mathieu Durand, Marc-Alexandre Olivier, Alicia Pellerin-Viger, Francis Rodier, Benoit Chabot

Aging Cell· November 2024

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Regulatory interplay between SR proteins governs kinase splice variants production.
Lulzim Shkreta, Aurélie Delannoy, Johanne Toutant, Benoit Chabot

RNA· November 2024

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The dual-specificity kinase DYRK1A interacts with the Hepatitis B virus genome and regulates the production of viral RNA.
Florentin Pastor, Emilie Charles, Chiara Di Vona, Maëlys Chapelle, Michel Rivoire, Benoit Chabot

PLoS One· October 2024

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Intron Retention of DDX39A Driven by SNRPD2 is a Crucial Splicing Axis for Oncogenic MYC/Spliceosome Program in Hepatocellular Carcinoma.
Cunjie Chang, Lina Li, Ling Su, Fan Yang, Quanxiu Zha, Benoit Chabot

Adv Sci (Weinh)· September 2024

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The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.
Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Benoit Chabot

Oncotarget· May 2024

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Total liquid ventilation in an ovine model of extreme prematurity: a randomized study.
Christophe Morin, Émile Simard, Wendy See, Michaël Sage, Roqaya Imane, Benoît Chabot

Pediatr Res· March 2024

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On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine.
Subha Dahal, Kiera Clayton, Tyler Cabral, Ran Cheng, Shahrzad Jahanshahi, Benoit Chabot

J Virol· October 2023

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The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress.
Florence Lemaitre, Fatima Chakrama, Tina O'Grady, Olivier Peulen, Gilles Rademaker, Benoit Chabot

Nucleic Acids Res· December 2022

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Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.
Subha Dahal, Kiera Clayton, Terek Been, Raphaële Fernet-Brochu, Alonso Villasmil Ocando, Benoit Chabot

Retrovirology· August 2022

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The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.
Cunjie Chang, Muthukumar Rajasekaran, Yiting Qiao, Heng Dong, Yu Wang, Benoit Chabot

Nat Commun· March 2022

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The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.
Subha Dahal, Ran Cheng, Peter K Cheung, Terek Been, Ramy Malty, Benoit Chabot

Viruses· December 2021

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SRSF10: an atypical splicing regulator with critical roles in stress response, organ development, and viral replication.
Lulzim Shkreta, Aurélie Delannoy, Anna Salvetti, Benoit Chabot

RNA· November 2021

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2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing.
Maryam Zamiri, Peter K Cheung, Mark A Brockman, Zabrina L Brumme, Benoit Chabot

ACS Med Chem Lett· November 2021

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A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
Muhammad Sohail, Lulzim Shkreta, Johanne Toutant, Safwat Rabea, Jean-Philippe Babeu, Benoit Chabot

NAR Cancer· June 2021

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Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond.
Florentin Pastor, Lulzim Shkreta, Benoit Chabot, David Durantel, Anna Salvetti

Front Microbiol· March 2021

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Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production.
Hélène Chabrolles, Héloïse Auclair, Serena Vegna, Thomas Lahlali, Caroline Pons, Benoit Chabot

PLoS Pathog· November 2020

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Effect of Low Versus High Tidal-Volume Total Liquid Ventilation on Pulmonary Inflammation.
Michaël Sage, Wendy See, Stéphanie Nault, Christophe Morin, Christina Michalski, Benoit Chabot

Front Physiol· June 2020

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NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
Sami Nourreddine, Geneviève Lavoie, Justine Paradis, Khaled Ben El Kadhi, Antoine Méant, Benoit Chabot

Cell Rep· May 2020

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Editorial - splicing and alternative splicing.
Jose-Luis Capelo-Martinez, Benoit Chabot, Carlos Lodeiro Espiño, Hugo Miguel Baptista Carreira Dos Santos

Int J Biochem Cell Biol· August 2019

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Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.
Martine Tétreault, Jade-Emmanuelle Deshaies, Sabrina Semmler, Hadjara Sidibé, Lulzim Shkreta, Benoit Chabot

Brain· December 2018

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TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
Jade-Emmanuelle Deshaies, Lulzim Shkreta, Alexander J Moszczynski, Hadjara Sidibé, Sabrina Semmler, Benoit Chabot

Brain· May 2018

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hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.
Alexandre Cloutier, Lulzim Shkreta, Johanne Toutant, Mathieu Durand, Philippe Thibault, Benoit Chabot

Sci Rep· February 2018

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RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells.
Emma Bondy-Chorney, R Mitchell Baldwin, Andréanne Didillon, Benoît Chabot, Bernard J Jasmin

Int J Biochem Cell Biol· October 2017

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Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.
Leslie C Sutherland, Philippe Thibault, Mathieu Durand, Elvy Lapointe, Jose M Knee, Benoit Chabot

BMC Mol Biol· July 2017

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