Publications by authors named "Benoit Drolet"

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A Physicochemical Stability Study of Pembrolizumab Vial Leftovers: Let Us Stop Pouring Good Money Down the Drain.
Alexandra Porlier, Pierre-Yves Gagnon, Valérie Chénard, Marc Veillette, Nicolas Bertrand, Benoît Drolet

Pharmacy (Basel)· February 2025

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Stability of Opened Durvalumab (IMFINZI) Vials. The Beginning of the End of Costly Product Wastage?
Alexandra Porlier, Pierre-Yves Gagnon, Valérie Chénard, Marc Veillette, Nicolas Bertrand, Benoit Drolet

J Pharm Sci· September 2023

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Overview of Cardiac Arrhythmias and Treatment Strategies.
John Kingma, Chantale Simard, Benoît Drolet

Pharmaceuticals (Basel)· June 2023

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Remdesivir (VEKLURY) for Treating COVID-19: Guinea Pig Ex Vivo and In Vivo Cardiac Electrophysiological Effects.
Sylvie Pilote, Chantale Simard, Benoit Drolet

J Cardiovasc Pharmacol· October 2022

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SCN5A-C683R exhibits combined gain-of-function and loss-of-function properties related to adrenaline-triggered ventricular arrhythmia.
Christian Steinberg, Sylvie Pilote, François Philippon, Zachary W Laksman, Jean Champagne, Benoît Drolet

Exp Physiol· March 2021

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Tacrolimus Dose-Conversion Ratios Based on Switching of Formulations for Patients with Solid Organ Transplants.
Wen-Yuan Johnson Kuan, Nathalie Châteauvert, Vincent Leclerc, Benoît Drolet

Can J Hosp Pharm· January 2021

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The Physiopathology of Cardiorenal Syndrome: A Review of the Potential Contributions of Inflammation.
John G Kingma, Denys Simard, Jacques R Rouleau, Benoit Drolet, Chantale Simard

J Cardiovasc Dev Dis· November 2017

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Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes-A Link in the Onset and Development of Cardiovascular Disease?
Benoit Drolet, Sylvie Pilote, Carolanne Gélinas, Alida-Douce Kamaliza, Audrey Blais-Boilard

Pharmaceutics· October 2017

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Fingolimod (Gilenya ) in multiple sclerosis: bradycardia, atrioventricular blocks, and mild effect on the QTc interval. Something to do with the L-type calcium channel?
Sylvie Pilote, Chantale Simard, Benoit Drolet

Fundam Clin Pharmacol· August 2017

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The guinea-pig expresses functional CYP2C and P-glycoprotein: further validation of its usefulness in drug biotransformation/transport studies.
Ibrahim Hasibu, Dany Patoine, Sylvie Pilote, Benoit Drolet, Chantale Simard

Biopharm Drug Dispos· April 2015

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Modulation of CYP3a expression and activity in mice models of type 1 and type 2 diabetes.
Dany Patoine, Michaël Petit, Sylvie Pilote, Frédéric Picard, Benoit Drolet

Pharmacol Res Perspect· December 2014

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Decreased CYP3A expression and activity in guinea pig models of diet-induced metabolic syndrome: is fatty liver infiltration involved?
Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet, Chantale Simard

Drug Metab Dispos· May 2013

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QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.
Bertrand Caillier, Sylvie Pilote, Annie Castonguay, Dany Patoine, Verlaine Ménard-Desrosiers, Benoit Drolet

Fundam Clin Pharmacol· October 2012

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Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
Patrick Vigneault, Sylvie Pilote, Dany Patoine, Chantale Simard, Benoit Drolet

Pharmacol Res· July 2012

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Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current.
Patrick Vigneault, Sarah Bourgault, Nisrin Kaddar, Bertrand Caillier, Sylvie Pilote, Benoit Drolet

Eur J Pharmacol· April 2012

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Tizanidine (Zanaflex): a muscle relaxant that may prolong the QT interval by blocking IKr.
Nisrin Kaddar, Patrick Vigneault, Sylvie Pilote, Dany Patoine, Chantale Simard, Benoit Drolet

J Cardiovasc Pharmacol Ther· March 2012

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Metabolic syndrome potentiates the cardiac action potential-prolonging action of drugs: a possible 'anti-proarrhythmic' role for amlodipine.
Bertrand Caillier, Sylvie Pilote, Dany Patoine, Xavier Levac, Christian Couture, Benoit Drolet

Pharmacol Res· March 2012

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Rosuvastatin blocks hERG current and prolongs cardiac repolarization.
Isabelle Plante, Patrick Vigneault, Benoît Drolet, Jacques Turgeon

J Pharm Sci· February 2012

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Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?
Patrick Vigneault, Nisrin Kaddar, Sarah Bourgault, Bertrand Caillier, Sylvie Pilote, Benoit Drolet

J Cardiovasc Pharmacol· June 2011

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A novel KCNQ1 variant (L203P) associated with torsades de pointes-related syncope in a Steinert syndrome patient.
Dany Patoine, Ibrahim Hasibu, Sylvie Pilote, Jean Champagne, Benoit Drolet

Can J Cardiol· June 2011

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Lengthening of cardiac repolarization in isolated guinea pigs hearts by sequential or concomitant administration of two IKr blockers.
Raymond Hreiche, Isabelle Plante, Benoit Drolet, Pierre Morissette, Jacques Turgeon

J Pharm Sci· June 2011

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Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents.
Raymond Hreiche, Isabelle Plante, Louis-Philippe David, Chantale Simard, Jacques Turgeon, Benoit Drolet

J Mol Cell Cardiol· August 2009

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Verapamil-associated cardiogenic shock in a 71-year-old man with myasthenia gravis: a case report.
Benoit Drolet, Geneviève Gabra, Chantale Simard, Bernard Noël, Paul Poirier

J Med Case Rep· June 2009

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Ischemic, genetic and pharmacological origins of cardiac arrhythmias: the contribution of the Quebec Heart Institute.
Benoît Drolet, Chantale Simard, Laimonis Gailis, Pascal Daleau

Can J Cardiol· October 2007

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The Brugada syndrome in Canada: a unique French-Canadian experience.
Jean Champagne, François Philippon, Marcel Gilbert, Franck Molin, Louis Blier, Benoit Drolet

Can J Cardiol· October 2007

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