Publications by authors named "Benoit Hastoy"

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Mitochondrial movement in pancreatic alpha cells requires Miro2 and is regulated by glucose.
Maia H Ekstrand, Sameena Nawaz, Anne Clark, Benoit Hastoy, Jakob G Knudsen

J Biol Chem· November 2025

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Ticking Differently: Elucidating Sexual Dimorphism in Human Aging through Metabolomics, Proteomics and Genomics.
Sihao Xiao, Pallavi Kaushik, Gaoyu Du, Bowen Liu, Salman B Hosawi, Benoit Hastoy

medRxiv· October 2025

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Roles for the long non-coding RNA / in pancreatic beta cell function.
Livia Lopez-Noriega, Rebecca Callingham, Aida Martinez-Sánchez, Sameena Nawaz, Grazia Pizza, Benoit Hastoy

iScience· January 2025

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Electrophysiological Characterization of Inducible Pluripotent Stem Cell-Derived Human β-Like Cells and an SLC30A8 Disease Model.
Manon Jaffredo, Nicole A J Krentz, Benoite Champon, Claire E Duff, Sameena Nawaz, Benoit Hastoy

Diabetes· August 2024

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Electrophysiological characterisation of iPSC-derived human β-like cells and an disease model.
Manon Jaffredo, Nicole A J Krentz, Benoite Champon, Claire E Duff, Sameena Nawaz, Benoit Hastoy

bioRxiv· October 2023

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Platelet-derived lipids promote insulin secretion of pancreatic β cells.
Till Karwen, Katarzyna Kolczynska-Matysiak, Carina Gross, Mona C Löffler, Mike Friedrich, Benoit Hastoy

EMBO Mol Med· September 2023

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Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists.
Mahesh M Umapathysivam, Elisa Araldi, Benoit Hastoy, Adem Y Dawed, Hasan Vatandaslar

medRxiv· April 2023

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Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca sensitivity but has limited effect on systemic metabolism.
Kerry McLaughlin, Samuel Acreman, Sameena Nawaz, Joseph Cutteridge, Anne Clark, Benoit Hastoy

Diabet Med· December 2022

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Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.
Ming Hu, Inês Cebola, Gaelle Carrat, Shuying Jiang, Sameena Nawaz, Benoit Hastoy

Cell Rep· March 2021

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Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.
Ming Hu, Inês Cebola, Gaelle Carrat, Shuying Jiang, Sameena Nawaz, Benoit Hastoy

Cell Rep· February 2021

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Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.
Julia Ast, Anastasia Arvaniti, Nicholas H F Fine, Daniela Nasteska, Fiona B Ashford, Benoit Hastoy

Nat Commun· October 2020

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A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function.
Antje K Grotz, Fernando Abaitua, Elena Navarro-Guerrero, Benoit Hastoy, Daniel Ebner

Wellcome Open Res· April 2020

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Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.
Julia Ast, Anastasia Arvaniti, Nicholas H F Fine, Daniela Nasteska, Fiona B Ashford, Benoit Hastoy

Nat Commun· January 2020

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.
Om Prakash Dwivedi, Mikko Lehtovirta, Benoit Hastoy, Vikash Chandra, Nicole A J Krentz

Nat Genet· November 2019

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The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment.
Zahia Fezoua-Boubegtiten, Benoit Hastoy, Pier Scotti, Alexandra Milochau, Katell Bathany

Biochim Biophys Acta Biomembr· March 2019

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Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.
Elisa Vergari, Jakob G Knudsen, Reshma Ramracheya, Albert Salehi, Quan Zhang, Benoit Hastoy

Nat Commun· January 2019

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Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells.
Benoît Hastoy, Mahdieh Godazgar, Anne Clark, Vibe Nylander, Ioannis Spiliotis

Sci Rep· November 2018

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Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
Soren K Thomsen, Anne Raimondo, Benoit Hastoy, Shahana Sengupta, Xiao-Qing Dai

Nat Genet· August 2018

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NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations.
Shailesh Kumar Gupta, Agata Wesolowska-Andersen, Anna K Ringgaard, Himjyot Jaiswal, Luyan Song, Benoit Hastoy

Stem Cell Res· May 2018

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AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity.
Caroline M Gorvin, Angela Rogers, Benoit Hastoy, Andrei I Tarasov, Morten Frost

Cell Rep· January 2018

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Fusion pore in exocytosis: More than an exit gate? A β-cell perspective.
Benoit Hastoy, Anne Clark, Patrik Rorsman, Jochen Lang

Cell Calcium· December 2017

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The β-cell assassin: IAPP cytotoxicity.
Daniel Raleigh, Xiaoxue Zhang, Benoît Hastoy, Anne Clark

J Mol Endocrinol· October 2017

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A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis.
Benoît Hastoy, Pier A Scotti, Alexandra Milochau, Zahia Fezoua-Boubegtiten, Jorge Rodas

Sci Rep· June 2017

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Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.
Stephan C Collins, Hyun Woong Do, Benoit Hastoy, Alison Hugill, Julie Adam

Diabetes· July 2016

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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Makoto Shigeto, Reshma Ramracheya, Andrei I Tarasov, Chae Young Cha, Margarita V Chibalina, Benoit Hastoy

J Clin Invest· December 2015

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