Publications by authors named "Benson Chen"

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The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people with relapsing-remitting multiple sclerosis already on disease-modifying therapy.
Gioia Riboni-Verri, Christopher E McMurran, Trisha Mukherjee, Cyrus Daruwalla, Jonathon Holland, Benson S Chen

Trials· December 2025

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Rasch analysis of the NEI-VFQ-25: vision-related quality of life in Leber hereditary optic neuropathy after lenadogene nolparvovec gene therapy.
Benson S Chen, Stéphanie Perot, Magali Taiel, Patrick Yu-Wai-Man, Mike Horton

BMJ Open Ophthalmol· September 2025

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"Adrift From the World": Exploring the Lived Experiences of Individuals Affected by an Inherited Optic Neuropathy in the United Kingdom-A Qualitative Study.
Benson S Chen, Chloe Seikus, James Ferguson, Valerija Tadić, Mike Horton

Value Health· August 2025

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Myelination of the retinal nerve fibre layer: A case report.
Gioia Riboni-Verri, Riddhima Gautam, Benson Chen, Nick G Cunniffe

Mult Scler· August 2025

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Technological advances in the diagnosis and management of inherited optic neuropathies.
John O T Britton, Patrick Yu-Wai-Man, Benson S Chen

Front Neurol· July 2025

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Clinical trials in Leber hereditary optic neuropathy: outcomes and opportunities.
Benson S Chen, Nancy J Newman

Curr Opin Neurol· February 2025

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Compositional Deep Probabilistic Models of DNA-Encoded Libraries.
Benson Chen, Mohammad M Sultan, Theofanis Karaletsos

J Chem Inf Model· February 2024

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Visual outcome measures in clinical trials of remyelinating drugs.
Gioia Riboni-Verri, Benson S Chen, Christopher E McMurran, Gregory J Halliwell, J William L Brown

BMJ Neurol Open· February 2024

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Mitochondria and the eye-manifestations of mitochondrial diseases and their management.
Benson S Chen, Joshua P Harvey, Michael J Gilhooley, Neringa Jurkute, Patrick Yu-Wai-Man

Eye (Lond)· August 2023

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Blurred Disc Margins.
John O T Britton, Patrick Yu-Wai-Man, Benson S Chen

J Neuroophthalmol· June 2023

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Childhood-Onset Leber Hereditary Optic Neuropathy-Clinical and Prognostic Insights.
Piero Barboni, Chiara La Morgia, Maria Lucia Cascavilla, Eun Hee Hong, Marco Battista, Benson S Chen

Am J Ophthalmol· May 2023

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DEL-Dock: Molecular Docking-Enabled Modeling of DNA-Encoded Libraries.
Kirill Shmilovich, Benson Chen, Theofanis Karaletsos, Mohammad M Sultan

J Chem Inf Model· May 2023

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Presumptive Idiopathic Intracranial Hypertension Based on Neuroimaging Findings: A Referral Pattern Study.
Andre B Aung, Benson S Chen, Jaime Wicks, Beau B Bruce, Benjamin I Meyer

J Neuroophthalmol· March 2023

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Expanding the clinical spectrum of idiopathic intracranial hypertension.
Benson S Chen, John O T Britton

Curr Opin Neurol· February 2023

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Psychometric Validity of the Visual Function Index in Leber Hereditary Optic Neuropathy.
Benson S Chen, Patrick Yu-Wai-Man, Mike Horton

Transl Vis Sci Technol· January 2023

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Intracranial computed tomography histogram analysis detects changes in the setting of elevated intracranial pressure and normal imaging.
Solmaz Asnafi, Benson S Chen, Valérie Biousse, Nancy J Newman, Amit M Saindane

Neuroradiol J· December 2022

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Developments in the Treatment of Leber Hereditary Optic Neuropathy.
Benson S Chen, Patrick Yu-Wai-Man, Nancy J Newman

Curr Neurol Neurosci Rep· December 2022

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The Impact of Leber Hereditary Optic Neuropathy on the Quality of Life of Patients and Their Relatives: A Qualitative Study.
Benson S Chen, Erik Holzinger, Magali Taiel, Patrick Yu-Wai-Man

J Neuroophthalmol· September 2022

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From Bench to Bedside-Delivering Gene Therapy for Leber Hereditary Optic Neuropathy.
Benson S Chen, Patrick Yu-Wai-Man

Cold Spring Harb Perspect Med· July 2022

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Capturing the experiences of patients with inherited optic neuropathies: a systematic review of patient-reported outcome measures (PROMs) and qualitative studies.
Benson S Chen, Tomasz Galus, Stephanie Archer, Valerija Tadić, Mike Horton

Graefes Arch Clin Exp Ophthalmol· June 2022

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Optic Nerve Angle in Idiopathic Intracranial Hypertension.
Benson S Chen, Solmaz Asnafi, Mung Y Lin, Beau B Bruce, Jane H Lock

J Neuroophthalmol· December 2021

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Wolfram syndrome: new pathophysiological insights and therapeutic strategies.
Ratnakar Mishra, Benson S Chen, Prachi Richa, Patrick Yu-Wai-Man

Ther Adv Rare Dis· August 2021

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Prevalence of Incidentally Detected Signs of Intracranial Hypertension on Magnetic Resonance Imaging and Their Association With Papilledema.
Benson S Chen, Benjamin I Meyer, Amit M Saindane, Beau B Bruce, Nancy J Newman

JAMA Neurol· June 2021

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Homonymous thinning on macular optical coherence tomography indicating retrograde trans-synaptic degeneration from occipital infarctions.
Benjamin I Meyer, Benson S Chen, Valérie Biousse, Nancy J Newman

Taiwan J Ophthalmol· January 2021

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Atypical presentations of idiopathic intracranial hypertension.
Benson S Chen, Nancy J Newman, Valérie Biousse

Taiwan J Ophthalmol· December 2020

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