Publications by authors named "Berit Powers"

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Acute neuronal inhibition response caused by phosphorothioate antisense oligonucleotides following local delivery to the central nervous system.
Jacqueline G O'Rourke, Gemma Bachmann, Curt Mazur, Keming Zhou, Oleksandr Platoshyn, Berit Powers

Nucleic Acids Res· January 2026

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Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of -related neurodevelopmental disorder.
Ane Korff, Xiaojing Yang, Ozan Ozdemir, Ananya Samanta, Yong-Dong Wang, Berit Powers

bioRxiv· November 2025

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Transient gene melting governs the timing of oligodendrocyte maturation.
Kevin C Allan, Jesse J Zhan, Andrew R Morton, Erin F Cohn, Marissa A Scavuzzo, Berit E Powers

Cell· October 2025

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Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy.
Sabrina Villar-Pazos, Laurel Thomas, Yunhan Yang, Kun Chen, Jenea B Lyles, Berit Powers

Nat Commun· October 2023

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RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice.
Sabrina Villar-Pazos, Laurel Thomas, Yunhan Yang, Kun Chen, Jenea B Lyles, Berit Powers

Res Sq· January 2023

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Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS.
Tetsuya Nagata, Chrissa A Dwyer, Kie Yoshida-Tanaka, Kensuke Ihara, Masaki Ohyagi, Berit Powers

Nat Biotechnol· December 2021

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Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment.
Tracy L Hagemann, Berit Powers, Ni-Hsuan Lin, Ahmed F Mohamed, Katerina L Dague

Sci Transl Med· November 2021

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The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration.
Paymaan Jafar-Nejad, Berit Powers, Armand Soriano, Hien Zhao, Daniel A Norris

Nucleic Acids Res· January 2021

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Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.
Matthew S Elitt, Lilianne Barbar, H Elizabeth Shick, Berit E Powers, Yuka Maeno-Hikichi

Nature· September 2020

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Convective forces increase rostral delivery of intrathecal radiotracers and antisense oligonucleotides in the cynomolgus monkey nervous system.
Jenna M Sullivan, Curt Mazur, Daniel A Wolf, Laura Horky, Nicolas Currier, Berit Powers

J Transl Med· August 2020

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Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging.
Curt Mazur, Berit Powers, Kenneth Zasadny, Jenna M Sullivan, Hemi Dimant

JCI Insight· October 2019

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Time-dependent, bidirectional, anti- and pro-spinal hyper-reflexia and muscle spasticity effect after chronic spinal glycine transporter 2 (GlyT2) oligonucleotide-induced downregulation.
Kota Kamizato, Silvia Marsala, Michael Navarro, Manabu Kakinohana, Oleksandr Platoshyn, Berit Powers

Exp Neurol· July 2018

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Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease.
Tracy L Hagemann, Berit Powers, Curt Mazur, Aneeza Kim, Steven Wheeler

Ann Neurol· January 2018

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Development of a simple, rapid, and robust intrathecal catheterization method in the rat.
Curt Mazur, Bethany Fitzsimmons, Fredrik Kamme, Brandon Nichols, Berit Powers

J Neurosci Methods· March 2017

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Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.
Jurate Lasiene, Okiru Komine, Noriko Fujimori-Tonou, Berit Powers, Fumito Endo

Acta Neuropathol Commun· February 2016

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A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.
Yin M Yang, Shailesh K Gupta, Kevin J Kim, Berit E Powers, Antonio Cerqueira

Cell Stem Cell· June 2013

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Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin.
Berit E Powers, Drew L Sellers, Emilie A Lovelett, Willy Cheung, Sheida P Aalami

Proc Natl Acad Sci U S A· March 2013

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Axonal thinning and extensive remyelination without chronic demyelination in spinal injured rats.
Berit E Powers, Jurate Lasiene, Jason R Plemel, Larry Shupe, Steve I Perlmutter

J Neurosci· April 2012

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