Publications by authors named "Beth A Weaver"

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Loss of negative regulation by HDAC1 and REST contributes to MAD1 overexpression in breast cancer.
Sarah E Copeland, Boya Chen, Avtar Roopra, Beth A Weaver

Mol Biol Cell· August 2025

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Correction: Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles.
Amber S Zhou, John B Tucker, Christina M Scribano, Andrew R Lynch, Caleb L Carlsen, Beth A Weaver

PLoS Biol· February 2025

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MAD1 upregulation sensitizes to inflammation-mediated tumor formation.
Sarah E Copeland, Santina M Snow, Jun Wan, Kristina A Matkowskyj, Richard B Halberg, Beth A Weaver

PLoS Genet· October 2024

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Chromosomal instability increases radiation sensitivity.
Pippa F Cosper, Maha Paracha, Kathryn M Jones, Laura Hrycyniak, Les Henderson, Beth A Weaver

bioRxiv· September 2024

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CENP-E Inhibition Induces Chromosomal Instability and Synergizes with Diverse Microtubule-Targeting Agents in Breast Cancer.
John B Tucker, Caleb L Carlsen, Christina M Scribano, Srishrika M Pattaswamy, Mark E Burkard, Beth A Weaver

Cancer Res· August 2024

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A survey of chromosomal instability measures across mechanistic models.
Andrew R Lynch, Shermineh Bradford, Amber S Zhou, Kim Oxendine, Les Henderson, Beth A Weaver

Proc Natl Acad Sci U S A· April 2024

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Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles.
Amber S Zhou, John B Tucker, Christina M Scribano, Andrew R Lynch, Caleb L Carlsen, Beth A Weaver

PLoS Biol· October 2023

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A survey of CIN measures across mechanistic models.
Andrew R Lynch, Shermineh Bradford, Amber S Zhou, Kim Oxendine, Les Henderson, Beth A Weaver

bioRxiv· June 2023

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HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E.
Pippa F Cosper, Laura C F Hrycyniak, Maha Paracha, Denis L Lee, Jun Wan, Beth A Weaver

Proc Natl Acad Sci U S A· April 2023

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Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer.
John B Tucker, Sarah C Bonema, Rebeca García-Varela, Ryan A Denu, Yang Hu, Beth A Weaver

Cancer Res Commun· January 2023

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Increased Aurora B expression reduces substrate phosphorylation and induces chromosomal instability.
Eric M C Britigan, Jun Wan, Daniel K Sam, Sarah E Copeland, Amber L Lasek, Beth A Weaver

Front Cell Dev Biol· October 2022

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Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference.
Andrew R Lynch, Nicholas L Arp, Amber S Zhou, Beth A Weaver, Mark E Burkard

Elife· April 2022

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Chromosome Missegregation as a Modulator of Radiation Sensitivity.
Pippa F Cosper, Sarah E Copeland, John B Tucker, Beth A Weaver

Semin Radiat Oncol· January 2022

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Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer.
Yang Hu, Baraa K Manasrah, Stephanie M McGregor, Robert F Lera, Roshan X Norman, Beth A Weaver

Mol Cancer Ther· December 2021

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Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.
Christina M Scribano, Jun Wan, Karla Esbona, John B Tucker, Amber Lasek, Beth A Weaver

Sci Transl Med· September 2021

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Recordings from neuron-HEK cell cocultures reveal the determinants of miniature excitatory postsynaptic currents.
Chung-Wei Chiang, Wen-Chi Shu, Jun Wan, Beth A Weaver, Meyer B Jackson

J Gen Physiol· May 2021

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High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability.
Daniel R Matson, Ryan A Denu, Lauren M Zasadil, Mark E Burkard, Beth A Weaver

BMC Cancer· February 2021

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p53 Is Not Required for High CIN to Induce Tumor Suppression.
Laura C Funk, Jun Wan, Sean D Ryan, Charanjeet Kaur, Ruth Sullivan, Beth A Weaver

Mol Cancer Res· January 2021

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Chromosomal instability upregulates interferon in acute myeloid leukemia.
Ning Jin, Robert F Lera, Rachel E Yan, Fen Guo, Kim Oxendine, Beth A Weaver

Genes Chromosomes Cancer· November 2020

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Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer.
Ashok Singh, Ryan A Denu, Serena K Wolfe, Jamie M Sperger, Jennifer Schehr, Beth A Weaver

Mol Oncol· August 2020

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A Genetic Toggle for Chemical Control of Individual Plk1 Substrates.
James M Johnson, Alexander S Hebert, Quentin H Drane, Robert F Lera, Jun Wan, Beth A Weaver

Cell Chem Biol· March 2020

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Banding Together: A Systematic Comparison of The Cancer Genome Atlas and the Mitelman Databases.
Connor Denomy, Samuel Germain, Bjorn Haave, Frederick S Vizeacoumar, Andrew Freywald, Beth A Weaver

Cancer Res· October 2019

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Mad1 destabilizes p53 by preventing PML from sequestering MDM2.
Jun Wan, Samuel Block, Christina M Scribano, Rebecca Thiry, Karla Esbona, Beth A Weaver

Nat Commun· April 2019

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Tuning Chromosomal Instability to Optimize Tumor Fitness.
Mark E Burkard, Beth A Weaver

Cancer Discov· February 2017

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Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.
Laura C Funk, Lauren M Zasadil, Beth A Weaver

Dev Cell· December 2016

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