Publications by authors named "Beth Borowsky"

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Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies.
Pierre N Tariot, Marie-Emmanuelle Riviere, Stephen Salloway, Jeffrey M Burns, Jón G Snaedal, Beth Borowsky

Alzheimers Dement· November 2024

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Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study.
Ralf Reilmann, Karen E Anderson, Andrew Feigin, Sarah J Tabrizi, Blair R Leavitt, Beth Borowsky

Lancet Neurol· March 2024

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A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod.
Andreas-Antonios Roussakis, Marta Gennaro, Mark Forrest Gordon, Ralf Reilmann, Beth Borowsky

Brain Commun· April 2023

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A biological classification of Huntington's disease: the Integrated Staging System.
Sarah J Tabrizi, Scott Schobel, Emily C Gantman, Alexandra Mansbach, Beth Borowsky

Lancet Neurol· July 2022

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An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion.
Caroline Gubser Keller, Youngah Shin, Alex Mas Monteys, Nicole Renaud, Martin Beibel, Beth Borowsky

Nat Commun· March 2022

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Longitudinal expression changes are weak correlates of disease progression in Huntington's disease.
Christopher T Mitchell, Irina Krier, Jamshid Arjomand, Beth Borowsky, Sarah J Tabrizi

Brain Commun· October 2020

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Association of CAG Repeats With Long-term Progression in Huntington Disease.
Douglas R Langbehn, Julie C Stout, Sarah Gregory, James A Mills, Alexandra Durr, Beth Borowsky

JAMA Neurol· November 2019

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Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study.
Ralf Reilmann, Andrew McGarry, Igor D Grachev, Juha-Matti Savola, Beth Borowsky

Lancet Neurol· February 2019

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Design optimization for clinical trials in early-stage manifest Huntington's disease.
Chris Frost, Amy Mulick, Rachael I Scahill, Gail Owen, Elizabeth Aylward, Beth Borowsky

Mov Disord· November 2017

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Longitudinal changes in the fronto-striatal network are associated with executive dysfunction and behavioral dysregulation in Huntington's disease: 30 months IMAGE-HD data.
Juan F Domínguez D, Govinda Poudel, Julie C Stout, Marcus Gray, Phyllis Chua, Beth Borowsky

Cortex· July 2017

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Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease.
Michael Orth, Sarah Gregory, Rachael I Scahill, Isabella Sm Mayer, Lora Minkova, Beth Borowsky

Hum Brain Mapp· December 2016

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A Computational Cognitive Biomarker for Early-Stage Huntington's Disease.
Thomas V Wiecki, Chrystalina A Antoniades, Alexander Stevenson, Christopher Kennard, Beth Borowsky

PLoS One· July 2016

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Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington's Disease.
Izelle Labuschagne, Amy Mulick Cassidy, Rachael I Scahill, Eileanoir B Johnson, Elin Rees, Beth Borowsky

J Int Neuropsychol Soc· July 2016

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Medication Use in Early-HD Participants in Track-HD: an Investigation of its Effects on Clinical Performance.
Ruth Keogh, Chris Frost, Gail Owen, Rhian M Daniel, Doug R Langbehn, Beth Borowsky

PLoS Curr· January 2016

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Sleep deficits but no metabolic deficits in premanifest Huntington's disease.
Alpar S Lazar, Francesca Panin, Anna O G Goodman, Stanley E Lazic, Zsolt I Lazar, Beth Borowsky

Ann Neurol· October 2015

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Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study.
Stefan Klöppel, Sarah Gregory, Elisa Scheller, Lora Minkova, Adeel Razi, Beth Borowsky

EBioMedicine· October 2015

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Functional changes during working memory in Huntington's disease: 30-month longitudinal data from the IMAGE-HD study.
Govinda R Poudel, Julie C Stout, D Juan F Domínguez, Marcus A Gray, Louisa Salmon, Beth Borowsky

Brain Struct Funct· January 2015

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HD-CAB: a cognitive assessment battery for clinical trials in Huntington's disease 1,2,3.
Julie C Stout, Sarah Queller, Kalyca N Baker, Sean Cowlishaw, Cristina Sampaio, Beth Borowsky

Mov Disord· September 2014

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Clinical trials in Huntington's disease: Interventions in early clinical development and newer methodological approaches.
Cristina Sampaio, Beth Borowsky, Ralf Reilmann

Mov Disord· September 2014

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Functional and connectivity changes during working memory in Huntington's disease: 18 month longitudinal data from the IMAGE-HD study.
Nellie Georgiou-Karistianis, Govinda R Poudel, Juan F Domínguez D, Rebecca Langmaid, Marcus A Gray, Beth Borowsky

Brain Cogn· October 2013

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Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Sarah J Tabrizi, Rachael I Scahill, Gail Owen, Alexandra Durr, Blair R Leavitt, Beth Borowsky

Lancet Neurol· July 2013

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8OHdG is not a biomarker for Huntington disease state or progression.
Beth Borowsky, John Warner, Blair R Leavitt, Sarah J Tabrizi, Raymund A C Roos

Neurology· May 2013

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Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data.
Sarah J Tabrizi, Ralf Reilmann, Raymund A C Roos, Alexandra Durr, Blair Leavitt, Beth Borowsky

Lancet Neurol· January 2012

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Assessment of cognitive symptoms in prodromal and early huntington disease.
Anthony L Vaccarino, Terrence Sills, Karen E Anderson, Beth Borowsky, David Craufurd

PLoS Curr· October 2011

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Assessing behavioural manifestations prior to clinical diagnosis of huntington disease: "anger and irritability" and "obsessions and compulsions".
Anthony L Vaccarino, Anonymous, Karen E Anderson, Beth Borowsky, Emil Coccaro

PLoS Curr· July 2011

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