Publications by authors named "Beth Coughlin"

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Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration.
Balasubramaniam Annamalai, Nathaniel Parsons, Crystal Nicholson, Kusumam Joseph, Beth Coughlin

Exp Eye Res· June 2021

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Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells.
Beth Coughlin, Gloriane Schnabolk, Kusumam Joseph, Himanshu Raikwar, Kannan Kunchithapautham

Sci Rep· March 2016

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Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization.
Gloriane Schnabolk, Beth Coughlin, Kusumam Joseph, Kannan Kunchithapautham, Mausumi Bandyopadhyay

Invest Ophthalmol Vis Sci· January 2015

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A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization.
Gloriane Schnabolk, Kimberly Stauffer, Elizabeth O'Quinn, Beth Coughlin, Kannan Kunchithapautham

Exp Eye Res· December 2014

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Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury.
Alex Woodell, Beth Coughlin, Kannan Kunchithapautham, Sarah Casey, Tucker Williamson

PLoS One· February 2014

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Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
Kusumam Joseph, Liudmila Kulik, Beth Coughlin, Kannan Kunchithapautham, Mausumi Bandyopadhyay

J Biol Chem· May 2013

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Detection of complement activation using monoclonal antibodies against C3d.
Joshua M Thurman, Liudmila Kulik, Heather Orth, Maria Wong, Brandon Renner, Beth Coughlin

J Clin Invest· May 2013

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Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization.
Bärbel Rohrer, Beth Coughlin, Mausumi Bandyopadhyay, V Michael Holers

J Ocul Pharmacol Ther· August 2012

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Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.
Kannan Kunchithapautham, Beth Coughlin, John J Lemasters, Bärbel Rohrer

Invest Ophthalmol Vis Sci· May 2011

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The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization.
Bärbel Rohrer, Beth Coughlin, Kannan Kunchithapautham, Qin Long, Stephen Tomlinson

Mol Immunol· March 2011

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A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Bärbel Rohrer, Qin Long, Beth Coughlin, Brandon Renner, Yuxiang Huang

Adv Exp Med Biol· January 2011

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Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.
Kannan Kunchithapautham, Beth Coughlin, Rosalie K Crouch, Bärbel Rohrer

Invest Ophthalmol Vis Sci· October 2009

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A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Bärbel Rohrer, Qin Long, Beth Coughlin, R Brooks Wilson, Yuxiang Huang

Invest Ophthalmol Vis Sci· July 2009

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