Publications by authors named "Bi-He Cai"

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Strategies for Anticancer Treatment in p53-Mutated Head and Neck Squamous Cell Carcinoma.
Bi-He Cai, Chia-Chi Chen, Yu-Te Sung, Yu-Chen Shih, Ching-Feng Lien

Biomedicines· May 2025

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Synergistic Anticancer Activity of HSP70 Inhibitor and Doxorubicin in Gain-of-Function Mutated p53 Breast Cancer Cells.
Kuan-Yo Wu, Ana Crucho, Mia Su, Sih-Tong Chen, Chen-Hsiu Hung, Bi-He Cai

Biomedicines· April 2025

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Chlorophyllides repress gain-of-function p53 mutated HNSCC cell proliferation via activation of p73 and repression of p53 aggregation in vitro and in vivo.
Bi-He Cai, Yi-Ting Wang, Chia-Chi Chen, Fang-Yu Yeh, Yu-Rou Lin

Biochim Biophys Acta Mol Basis Dis· March 2025

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Analysis of Prognostic Factors for Internal Carotid Artery Invasion by Nasopharyngeal Carcinoma.
Ching-Feng Lien, Shyh-An Yeh, Chiu-Shih Cheng, Feng-Yu Chiang, Tzer-Zen Hwang, Bi-He Cai

Cancers (Basel)· February 2025

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The Competition of Yin and Yang: Exploring the Role of Wild-Type and Mutant p53 in Tumor Progression.
Bi-He Cai, Yu-Te Sung, Chia-Chi Chen, Jei-Fu Shaw, I-Lun Hsin

Biomedicines· April 2023

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A Simple and Affordable Method to Create Nonsense Mutation Clones of p53 for Studying the Premature Termination Codon Readthrough Activity of PTC124.
Chia-Chi Chen, Ruo-Yu Liao, Fang-Yu Yeh, Yu-Rou Lin, Tze-You Wu, Bi-He Cai

Biomedicines· April 2023

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PTC124 Rescues Nonsense Mutation of Two Tumor Suppressor Genes and to Repress HNSCC Cell Proliferation.
Ming-Han Wu, Rui-Yu Lu, Si-Jie Yu, Yi-Zhen Tsai, Ying-Chen Lin, Bi-He Cai

Biomedicines· November 2022

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P63 and P73 Activation in Cancers with p53 Mutation.
Bi-He Cai, Yun-Chien Hsu, Fang-Yu Yeh, Yu-Rou Lin, Rui-Yu Lu

Biomedicines· June 2022

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NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner.
Bi-He Cai, Zhi-Yu Bai, Ching-Feng Lien, Si-Jie Yu, Rui-Yu Lu

Biomolecules· March 2022

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BGN/TLR4/NF-B Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells.
Hsiang-Chi Huang, Bi-He Cai, Ching-Shu Suen, Hsueh-Yi Lee, Ming-Jing Hwang

Cells· February 2020

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SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Bi-He Cai, Hsueh-Yi Lee, Chi-Kan Chou, Po-Han Wu, Hsiang-Chi Huang

Cells· January 2020

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Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation.
Bi-He Cai, Chung-Faye Chao, Hsiang-Chi Huang, Hsueh-Yi Lee, Reiji Kannagi

Int J Mol Sci· July 2019

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Gangliosides and Tumors.
Reiji Kannagi, Bi-He Cai, Hsiang-Chi Huang, Chia-Chun Chao, Keiichiro Sakuma

Methods Mol Biol· March 2019

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Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF-κB/EZH2/YY1 axis in early-stage colon cancers.
Hsiang-Chi Huang, Chia-Chun Chao, Po-Han Wu, Hsiao-Yu Chung, Hsueh-Yi Lee, Bi-He Cai

Biochim Biophys Acta Gene Regul Mech· February 2019

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Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells.
Bi-He Cai, Po-Han Wu, Chi-Kan Chou, Hsiang-Chi Huang, Chia-Chun Chao

Sci Rep· January 2019

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Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer.
Chia-Chun Chao, Po-Han Wu, Hsiang-Chi Huang, Hsiao-Yu Chung, Yu-Chi Chou, Bi-He Cai

FEBS Lett· July 2017

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A/T gap tolerance in the core sequence and flanking sequence requirements of non-canonical p53 response elements.
Bi-He Cai, Chung-Faye Chao, Hwang-Chi Lin, Hua-Ying Huang, Reiji Kannagi

J Biochem· June 2016

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p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation.
Bi-He Cai, Pei-Ching Hsu, I-Lun Hsin, Chung-Faye Chao, Mei-Hua Lu

PLoS One· February 2013

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A half-site of the p53-binding site on the keratin 14 promoter is specifically activated by p63.
Bi-He Cai, Chung-Faye Chao, Mei-Hua Lu, Hwang-Chi Lin, Jang-Yi Chen

J Biochem· July 2012

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Functional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53.
Bi-He Cai, Jang-Yi Chen, Mei-Hua Lu, Li-Tze Chang, Hwang-Chi Lin

Nucleic Acids Res· April 2009

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