Publications by authors named "Binbin Cheng"

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Novel imidazo[1,2-a]pyridine-based tubulin polymerization inhibitors: Structure-activity relationships and anti-tumor immune potentiation.
Binbin Cheng, Chao Li, Xixiang Yang, Yinrong Wu, Yong Ruan

Eur J Med Chem· January 2026

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Arsenic trioxide enhances the inhibitory effect of lenvatinib on hepatocellular carcinoma through HMOX1-mediated ferroptosis.
Shufang Liang, Guokai Huang, Meihuan Fu, Yuanrong Shi, Xiaoyu Tu, Binbin Cheng

Int Immunopharmacol· December 2025

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Recent advances in radionuclide drug conjugates (RDCs) for cancer theranostics: From targeted design to clinical translation.
Liu Xijing, Binbin Cheng

Bioorg Chem· December 2025

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Rational design of NAMPT-based dual inhibitors with improved drug-like and pharmacokinetic properties for cancer treatment.
Jinke Lv, Binbin Cheng, Changshan Song

Eur J Med Chem· November 2025

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Spop-binding bifunctional degraders: a novel approach for cancer immunotherapy.
Binbin Cheng, Zhihua Kong, Yaru Shi, Yinrong Wu, Jing-Jing Du

J Adv Res· November 2025

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Dihydroartemisinin decreases pre-existing neutralizing antibodies against adeno-associated virus in challenged mice.
Jingjing Fang, Enze Cui, Jinyan Xie, Xuxia Gao, Yun He, Binbin Cheng

Front Pharmacol· September 2025

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Research Progress in Targeting GSPT1: Molecular Glues, Bifunctional Degraders, and Antibody-Enabled Molecular Glues for Cancer Therapy.
Binbin Cheng, Yaping Wang, Yimeng Hong, Yingxing Zhou, Jianjun Chen

J Med Chem· July 2025

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Correction to "Small-Molecule Modulators Targeting Coactivator-Associated Arginine Methyltransferase 1 (CARM1) as Therapeutic Agents for Cancer Treatment: Current Medicinal Chemistry Insights and Emerging Opportunities".
Shuqing Li, Wanyi Pan, Chengpeng Tao, Zhihao Hu, Binbin Cheng

J Med Chem· July 2025

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Oleanolic acid inhibits M2 macrophage polarization and potentiates anti-PD-1 therapy in hepatocellular carcinoma by targeting miR-130b-3p-PTEN-PI3K-Akt signaling and glycolysis.
Xiaoyu Tu, Wanfu Lin, Xiaofeng Zhai, Shufang Liang, Guokai Huang, Binbin Cheng

Phytomedicine· June 2025

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Discovery of Small Molecule PD-L1 Inhibitors via Optimization of Solvent-Interaction Region for Cancer Immunotherapy.
Binbin Cheng, Ting Liu, Hao Cao, Jin Liu, Yichang Ren

Chem Biol Drug Des· June 2025

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Comprehensive secretome profiling and CRISPR screen identifies SFRP1 as a key inhibitor of epidermal progenitor proliferation.
Binbin Cheng, Shaohong Isaac Peng, Yunlong Y Jia, Elton Tong, Scott X Atwood

Cell Death Dis· May 2025

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Research progress in DNA damage response (DDR)-targeting modulators: From hits to clinical candidates.
Binbin Cheng, Zongbao Ding, Yimeng Hong, Yaping Wang, Yingxing Zhou

Eur J Med Chem· April 2025

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Discovery of highly potent dual GSPT1/BRD4 degraders with anti-AML activity.
Yue Xu, Hang Yang, Yunxuan Li, Yuying Qi, Fangling Zhao, Binbin Cheng

Eur J Med Chem· April 2025

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Discovery of bifunctional small molecules targeting PD-L1/VISTA with favorable pharmacokinetics for cancer immunotherapy.
Yao Xiao, Yaru Shi, Chuxiao Shao, Wubing Tang, Hao Liu, Binbin Cheng

Bioorg Chem· April 2025

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Small-Molecule Modulators Targeting Coactivator-Associated Arginine Methyltransferase 1 (CARM1) as Therapeutic Agents for Cancer Treatment: Current Medicinal Chemistry Insights and Emerging Opportunities.
Shuqing Li, Wanyi Pan, Chengpeng Tao, Zhihao Hu, Binbin Cheng

J Med Chem· March 2025

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Research progress in bifunctional small molecules for cancer immunotherapy.
Binbin Cheng, Hongqiao Li, Yimeng Hong, Yingxing Zhou, Jianjun Chen

Eur J Med Chem· March 2025

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Paeoniflorin inhibits chronic restraint stress-induced progression of hepatocellular carcinoma through suppressing norepinephrine-induced activation of hepatic stellate cells via SRC/AKT/ERK pathways.
Yujun Luo, Wanfu Lin, Shuang Xiang, Yuanrong Shi, Meihuan Fu, Binbin Cheng

J Ethnopharmacol· March 2025

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Discovery of Novel and Highly Potent Dual PD-L1/Histone Deacetylase 6 Inhibitors with Favorable Pharmacokinetics for Cancer Immunotherapy.
Zhihao Hu, Shuqing Li, Haiqi He, Wanyi Pan, Ting Liu, Chengpeng Tao, Binbin Cheng

J Med Chem· March 2025

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Small molecule inhibitors targeting PD-L1, CTLA4, VISTA, TIM-3, and LAG3 for cancer immunotherapy (2020-2024).
Binbin Cheng, Jinke Lv, Yao Xiao, Changshan Song, Jianjun Chen

Eur J Med Chem· February 2025

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Recent advances in developing targeted protein degraders.
Binbin Cheng, Hongqiao Li, Xiaopeng Peng, Jianjun Chen, Chuxiao Shao

Eur J Med Chem· February 2025

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Protein arginine methyltransferase 7 modulators in disease therapy: Current progress and emerged opportunity.
Dongmin Yu, Limei Zeng, Yuqi Wang, Binbin Cheng, Deping Li

Bioorg Chem· January 2025

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Overview of the PRMT6 modulators in cancer treatment: Current progress and emerged opportunity.
Jinjin Peng, Bin Ni, Deping Li, Binbin Cheng, Renze Yang

Eur J Med Chem· December 2024

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Jiedu recipe, a compound Chinese herbal medicine, suppresses hepatocellular carcinoma metastasis by inhibiting the release of tumor-derived exosomes in a hypoxic microenvironment.
Wen-Tao Jia, Shuang Xiang, Jin-Bo Zhang, Jia-Ying Yuan, Yu-Qian Wang, Bin-Bin Cheng

J Integr Med· November 2024

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Bioactive sphingolipids as emerging targets for signal transduction in cancer development.
Wentao Jia, Jiaying Yuan, Jinbo Zhang, Shu Li, Wanfu Lin, Binbin Cheng

Biochim Biophys Acta Rev Cancer· September 2024

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Geochronology, geochemistry, and geological significance of early Jurassic intrusive rocks in the Lesser Xing'an- Zhangguangcai Range, northeast China.
Zhonghai Zhao, Zhongju Li, Haina Li, Binbin Cheng, Yechang Yin

PLoS One· August 2024

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