Publications by authors named "Birgit Appl"

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Biliatresone induces cholangiopathy in C57BL/6J neonates.
Hans Christian Schmidt, Johanna Hagens, Pauline Schuppert, Birgit Appl, Laia Pagerols Raluy, Magdalena Trochimiuk, Clara Philippi, Zhongwen Li, Konrad Reinshagen, Christian Tomuschat

Sci Rep· June 2023

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DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis.
Jan-Fritjof Willemsen, Julia Wenskus, Moritz Lenz, Holger Rhode, Madgalena Trochimiuk, Birgit Appl

Front Immunol· January 2024

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Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions.
Julia Elrod, Annika Heuer, Jasmin Knopf, Janina Schoen, Lavinia Schönfeld, Birgit Appl

iScience· December 2023

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Immunofluorescence Imaging of Neutrophil Extracellular Traps in Human and Mouse Tissues.
Lavinia Schöenfeld, Birgit Appl, Laia Pagerols-Raluy, Annika Heuer, Konrad Reinshagen

J Vis Exp· August 2023

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Kigelia africana inhibits proliferation and induces cell death in stage 4 Neuroblastoma cell lines.
Sofia Ahrens, Birgit Appl, Magdalena Trochimiuk, Charlotte Dücker, Gemma Feixas Serra

Biomed Pharmacother· October 2022

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NET Release of Long-Term Surviving Neutrophils.
Jan Philipp Kolman, Laia Pagerols Raluy, Ingo Müller, Viacheslav O Nikolaev, Magdalena Trochimiuk, Birgit Appl

Front Immunol· May 2022

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Markers of neutrophil activation and extracellular trap formation predict appendicitis.
Michael Boettcher, Anna-Lisa Schacker, Melina Esser, Lavinia Schönfeld, Chinedu Ulrich Ebenebe, Birgit Appl

Surgery· February 2022

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Time- and dose-dependent inhibition of neutrophil extracellular trap formation by blocking of the interleukin-1 receptor.
Hannah Wadehn, Laia Pagerols Raluy, Jan Kolman, Charlotte Duecker, Magdalena Trochimiuk, Birgit Appl

Cent Eur J Immunol· December 2021

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The Inhibitory Effect of Curosurf and Alveofact on the Formation of Neutrophil Extracellular Traps.
Annabell Schulz, Laia Pagerols Raluy, Jan Philipp Kolman, Ingo Königs, Magdalena Trochimiuk, Birgit Appl

Front Immunol· June 2021

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Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice.
Annika Heuer, Carolin Stiel, Julia Elrod, Ingo Königs, Deirdre Vincent, Birgit Appl

Front Immunol· June 2021

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Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option.
Julian Trah, Jonas Arand, Jun Oh, Laia Pagerols-Raluy, Magdalena Trochimiuk, Birgit Appl

Sci Rep· November 2020

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Markers of neutrophil activation and extracellular traps formation are predictive of appendicitis in mice and humans: a pilot study.
Michael Boettcher, Melina Esser, Julian Trah, Stefan Klohs, Nariman Mokhaberi, Birgit Appl

Sci Rep· October 2020

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Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis.
Michaela Klinke, Deirdre Vincent, Magdalena Trochimiuk, Birgit Appl, Bastian Tiemann

Sci Rep· May 2020

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Degradation of Extracellular DNA Significantly Ameliorates Necrotizing Enterocolitis Severity in Mice.
Michaela Klinke, Deirdre Vincent, Magdalena Trochimiuk, Birgit Appl, Bastian Tiemann

J Surg Res· March 2019

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Vincristine resistance in relapsed neuroblastoma can be efficiently overcome by Smac mimetic LCL161 treatment.
Kristin Frommann, Birgit Appl, Patrick Hundsdoerfer, Konrad Reinshagen, Georg Eschenburg

J Pediatr Surg· October 2018

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NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans.
Deirdre Vincent, Michaela Klinke, Georg Eschenburg, Magdalena Trochimiuk, Birgit Appl

Sci Rep· August 2018

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Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage After Testicular Torsion in Rats.
Michael Boettcher, Dennis Meier, Miguel Jiménez-Alcázar, Georg Eschenburg, Stefan Mietzsch, Birgit Appl

Urology· November 2017

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Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α.
Doerte Langemann, Magdalena Trochimiuk, Birgit Appl, Patrick Hundsdoerfer, Konrad Reinshagen

Oncotarget· October 2017

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Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.
Safiullah Najem, Doerte Langemann, Birgit Appl, Magdalena Trochimiuk, Patrick Hundsdoerfer

Oncotarget· November 2016

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Modulation of Thrombosis Significantly Reduces Testicular Damage after Testicular Torsion in Rats: Anti-Thrombotic Treatment and Testicular Torsion.
Michael Boettcher, Tobias A Fuchs, Hansjörg Schäfer, Birgit Appl, Magdalena Trochimiuk

Urology· February 2016

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A chicken embryo model for the study of umbilical and supraumbilical body wall malformations.
Ina Ridderbusch, Robert Bergholz, Miriam Fattouh, Georg Eschenburg, Beate Roth, Birgit Appl

Eur J Pediatr Surg· June 2015

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Gut inflammation and expression of ICC in a fetal lamb model of fetoscopic intervention for gastroschisis.
Thomas Krebs, Michael Boettcher, Hansjörg Schäfer, Georg Eschenburg, Katharina Wenke, Birgit Appl

Surg Endosc· August 2014

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Taurolidine specifically inhibits growth of neuroblastoma cell lines in vitro.
Christian Luckert, Georg Eschenburg, Beate Roth, Birgit Appl, Konrad Reinshagen

J Pediatr Hematol Oncol· May 2014

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Mucosal loss with increased expression of IL-6, IL-8, and COX-2 in a formula-feeding only neonatal rat model of necrotizing enterocolitis.
Robert Bergholz, Marcus Zschiegner, Georg Eschenburg, Katharina Wenke, Bastian Tiemann, Birgit Appl

J Pediatr Surg· November 2013

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Abdominal wall incision with or without exteriorization of bowel: results from a fetal lamb model for the embryogenesis of gastroschisis.
Robert Bergholz, Thomas Krebs, Katharina Wenke, Michael Boettcher, Thomas Andreas, Birgit Appl

Fetal Diagn Ther· June 2013

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