Publications by authors named "Birgit Lahme"

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Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells.
Olav A Gressner, Birgit Lahme, Monika Siluschek, Axel M Gressner

Liver Int· July 2009

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Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes--but without modulating bone morphogenetic protein 7 signaling.
Olav A Gressner, Birgit Lahme, Monika Siluschek, Katharina Rehbein, Ralf Weiskirchen

Hepatology· June 2009

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Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs.
Olav A Gressner, Chunfang Gao, Katharina Rehbein, Birgit Lahme, Monika Siluschek

Liver Int· May 2009

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Intraperitoneal application of caffeine prevents D-galactosamine-induced hepatic expression of connective tissue growth factor (CTGF/CCN2) in the rat.
Olav A Gressner, Monika Siluschek, Birgit Lahme, Axel M Gressner

J Hepatol· May 2009

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Questioning the role of actinfree Gc-Globulin as actin scavenger in neurodegenerative central nervous system disease: relationship to S-100B levels and blood-brain barrier function.
Olav A Gressner, Marie-Claire Schifflers, Philipp Kim, Leo Heuts, Birgit Lahme

Clin Chim Acta· February 2009

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Activation of TGF-beta within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor.
Olav A Gressner, Birgit Lahme, Monika Siluschek, Katharina Rehbein, Jens Herrmann

J Cell Mol Med· December 2008

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Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression.
Olav A Gressner, Birgit Lahme, Monika Siluschek, Katharina Rehbein, Ralf Weiskirchen

Liver Int· November 2008

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Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways.
Olav A Gressner, Birgit Lahme, Katharina Rehbein, Monika Siluschek, Ralf Weiskirchen

J Hepatol· November 2008

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Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca(2+)-dependent interaction with the megalin/gp330 receptor.
Olav A Gressner, Birgit Lahme, Axel M Gressner

Clin Chim Acta· April 2008

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Evaluation of hepatotropic targeting properties of allogenic and xenogenic erythrocyte ghosts in normal and liver-injured rats.
Olav A Gressner, Birgit Lahme, Martin Koch, Axel M Gressner

Liver Int· February 2008

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Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes.
Olav A Gressner, Birgit Lahme, Ilhan Demirci, Axel M Gressner, Ralf Weiskirchen

J Hepatol· November 2007

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Loss of TGF-beta dependent growth control during HSC transdifferentiation.
Oliver Purps, Birgit Lahme, Axel M Gressner, Nadja M Meindl-Beinker, Steven Dooley

Biochem Biophys Res Commun· February 2007

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Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis.
Axel M Gressner, Eray Yagmur, Birgit Lahme, Olav Gressner, Sven Stanzel

Clin Chem· September 2006

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Variable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cells.
Axel M Gressner, Birgit Lahme, Steffen K Meurer, Olav Gressner, Ralf Weiskirchen

World J Gastroenterol· February 2006

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Elevation of Nepsilon-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis.
Eray Yagmur, Frank Tacke, Claudia Weiss, Birgit Lahme, Michael P Manns

Clin Biochem· January 2006

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N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug.
Steffen K Meurer, Birgit Lahme, Lidia Tihaa, Ralf Weiskirchen, Axel M Gressner

Biochem Pharmacol· October 2005

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Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor beta receptor signaling.
Steffen K Meurer, Lidia Tihaa, Birgit Lahme, Axel M Gressner, Ralf Weiskirchen

J Biol Chem· January 2005

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Expression of cytosolic and membrane associated tissue transglutaminase in rat hepatic stellate cells and its upregulation during transdifferentiation to myofibroblasts in culture.
Claudia Schnabel, Iris Sawitza, Carmen G. Tag, Birgit Lahme, Axel M. Gressner

Hepatol Res· March 2004

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Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells.
Monica Arias, Birgit Lahme, Eddy Van de Leur, Axel M Gressner, Ralf Weiskirchen

Cell Growth Differ· June 2002

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