Publications by authors named "Birgit Masjost"

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Cobalt-mediated [2+2+2] cycloaddition versus C-H and N-H activation of pyridones and pyrazinones with alkynes: an experimental study.
Corinne Aubert, Patrick Betschmann, Michael J Eichberg, Vincent Gandon, Thilo J Heckrodt, Birgit Masjost

Chemistry· November 2007

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Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants.
Christine B Breitenlechner, Walter-Gunar Friebe, Emmanuel Brunet, Guido Werner, Klaus Graul, Birgit Masjost

J Med Chem· January 2005

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Structure-based optimization of novel azepane derivatives as PKB inhibitors.
Christine B Breitenlechner, Thomas Wegge, Laurent Berillon, Klaus Graul, Klaus Marzenell, Birgit Masjost

J Med Chem· March 2004

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Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity.
Christian Lerner, Birgit Masjost, Armin Ruf, Volker Gramlich, Roland Jakob-Roetne

Org Biomol Chem· January 2003

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X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity.
Christian Lerner, Armin Ruf, Volker Gramlich, Birgit Masjost, Gerhard Zürcher

Angew Chem Int Ed Engl· November 2001

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X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann-La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing.
Christian Lerner, Armin Ruf, Volker Gramlich, Birgit Masjost, Gerhard Zürcher

Angew Chem Int Ed Engl· November 2001

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