Publications by authors named "Birte Hofmann"

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Pharmacokinetics, Safety, and Dialyzability of Gadoquatrane in Patients With Impaired Renal Function: A Comprehensive Investigation Using Clinical Trial Data, Modeling and Simulation, and In Vitro Data.
Tommaso Fadini, Gabriele Sutter, Stefan Klein, Eva Busemann, Esmée Vendel, Birte Maria Hofmann

Invest Radiol· November 2025

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Gadoquatrane in Contrast-enhanced Head-and-neck and Liver Magnetic Resonance Imaging: A Preclinical Dose-Response Study in Pigs.
Gregor Jost, Jessica Lohrke, Birte Maria Hofmann, Hubertus Pietsch

Invest Radiol· November 2025

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Relationship of Dose and Signal Enhancement Properties of Gadoquatrane, a New Tetrameric, Macrocyclic Gadolinium-Based Contrast Agent, Compared With Gadobutrol: A Randomized Crossover Study in Healthy Adults.
Birte M Hofmann, Kai Riecke, Stefan Klein, Mark A Klemens, Petra Palkowitsch

Invest Radiol· December 2024

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Pharmacokinetics, safety, and tolerability of the novel tetrameric gadolinium-based MRI contrast agent gadoquatrane in healthy Chinese and Japanese men: Two randomized dose-escalation studies including concentration-QTc modeling.
Xuemei He, Shunji Matsuki, Kexin Li, Yubin Sui, Kumi Matsuno, Birte Maria Hofmann

Eur J Pharm Sci· May 2024

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Pharmacokinetics, Safety, and Tolerability of the Novel Tetrameric, High-Relaxivity, Macrocyclic Gadolinium-Based Contrast Agent Gadoquatrane in Healthy Adults.
Birte Maria Hofmann, Kai Riecke, Stefan Klein, Matthias Berse, Antje Rottmann

Invest Radiol· February 2024

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Extended use of levonorgestrel-releasing intrauterine system (LNG-IUS) 52 mg: A population pharmacokinetic approach to estimate in vivo levonorgestrel release rates and systemic exposure including comparison with two other LNG-IUSs.
Jeffrey T Jensen, Isabel Reinecke, Teun M Post, Eeva Lukkari-Lax, Birte M Hofmann

Contraception· April 2023

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The effect of a combined indomethacin and levonorgestrel-releasing intrauterine system on short-term postplacement bleeding profile: a randomized proof-of-concept trial.
Lueder M Fels, Dustin Costescu, Carolina S Vieira, Jeffrey F Peipert, Eeva Lukkari-Lax, Birte M Hofmann

Am J Obstet Gynecol· March 2023

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Development of an Intrauterine Device Releasing Both Indomethacin and Levonorgestrel During the First Months of Use: Pharmacokinetic Characterization in Healthy Women.
Birte Maria Hofmann, Manja Ahola, Lueder M Fels, Stefan Klein, Bernhard Lindenthal

Clin Pharmacokinet· January 2023

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[Implications for health services research in GP practices using the example of an intervention study on palliative care].
Manuel Zimansky, Birte Hofmann, Nils Schneider, Stephanie Stiel

Z Evid Fortbild Qual Gesundhwes· August 2021

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Comparative pharmacokinetic analysis of levonorgestrel-releasing intrauterine systems and levonorgestrel-containing contraceptives with oral or subdermal administration route.
Birte Maria Hofmann, Dan Apter, Johannes Bitzer, Isabel Reinecke, Marco Serrani

Eur J Contracept Reprod Health Care· December 2020

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An Integrated Population Pharmacokinetic Analysis to Characterize Levonorgestrel Pharmacokinetics After Different Administration Routes.
Isabel Reinecke, Birte Hofmann, Emir Mesic, Henk-Jan Drenth, Dirk Garmann

J Clin Pharmacol· December 2018

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Pharmacokinetic overview of ethinyl estradiol dose and bioavailability using two transdermal contraceptive systems and a standard combined oral contraceptive.
Birte Hofmann, Isabel Reinecke, Barbara Schuett, Martin Merz, Christian Zurth

Int J Clin Pharmacol Ther· December 2014

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Plasma pharmacokinetics, whole-body distribution, metabolism, and radiation dosimetry of 68Ga bombesin antagonist BAY 86-7548 in healthy men.
Anne Roivainen, Esa Kähkönen, Pauliina Luoto, Sandra Borkowski, Birte Hofmann

J Nucl Med· June 2013

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Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Jens Hoffmann, Iduna Fichtner, Margit Lemm, Philip Lienau, Holger Hess-Stumpp, Birte Hofmann

Neuro Oncol· April 2009

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Optical molecular imaging of lymph nodes using a targeted vascular contrast agent.
Kai Licha, Niels Debus, Sonja Emig-Vollmer, Birte Hofmann, Michael Hasbach

J Biomed Opt· December 2005

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