Publications by authors named "Blythe D Sather"

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Impact of Gamma-Secretase Inhibition on Outcomes Following BCMA CAR-T Therapy in Multiple Myeloma: A Comparison of Two Phase 1 Trials.
Andrew J Portuguese, Sherilyn A Tuazon, Margot J Pont, Gabriel O Cole, Blythe D Sather

Transplant Cell Ther· December 2025

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A phase 1 trial of fully human BCMA CAR-T therapy for relapsed/refractory multiple myeloma with 5-year follow-up.
Sherilyn A Tuazon, Andrew J Portuguese, Margot J Pont, Andrew J Cowan, Gabriel O Cole, Blythe D Sather

Blood· July 2025

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γ-Secretase inhibitor in combination with BCMA chimeric antigen receptor T-cell immunotherapy for individuals with relapsed or refractory multiple myeloma: a phase 1, first-in-human trial.
Andrew J Cowan, Margot J Pont, Blythe D Sather, Cameron J Turtle, Brian G Till

Lancet Oncol· July 2023

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Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector.
Brenda J Seymour, Swati Singh, Hannah M Certo, Karen Sommer, Blythe D Sather

Mol Ther Methods Clin Dev· March 2021

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Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance.
Guillermo S Romano Ibarra, Biswajit Paul, Blythe D Sather, Patrick M Younan, Karen Sommer

Mol Ther Nucleic Acids· August 2016

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Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.
Blythe D Sather, Guillermo S Romano Ibarra, Karen Sommer, Gabrielle Curinga, Malika Hale

Sci Transl Med· September 2015

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Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells.
Cathy X Wang, Blythe D Sather, Xuefeng Wang, Jennifer Adair, Iram Khan

Blood· August 2014

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Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
Daniela A Bermejo, Shaun W Jackson, Melisa Gorosito-Serran, Eva V Acosta-Rodriguez, Maria C Amezcua-Vesely, Blythe D Sather

Nat Immunol· May 2013

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Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.
Alexander Astrakhan, Blythe D Sather, Byoung Y Ryu, Socheath Khim, Swati Singh

Blood· May 2012

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WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.
Shirly Becker-Herman, Almut Meyer-Bahlburg, Marc A Schwartz, Shaun W Jackson, Kelly L Hudkins, Blythe D Sather

J Exp Med· September 2011

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Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.
Blythe D Sather, Byoung Y Ryu, Brigid V Stirling, Mikhail Garibov, Hannah M Kerns

Mol Ther· March 2011

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Cellular requirements for diabetes induction in DO11.10xRIPmOVA mice.
Johnna D Wesley, Blythe D Sather, Nikole R Perdue, Steven F Ziegler, Daniel J Campbell

J Immunol· October 2010

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B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.
Hannah M Kerns, Byoung Y Ryu, Brigid V Stirling, Blythe D Sather, Alexander Astrakhan

Blood· March 2010

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Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease.
Blythe D Sather, Piper Treuting, Nikole Perdue, Mike Miazgowicz, Jason D Fontenot

J Exp Med· June 2007

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Regulatory T cells maintain long-term tolerance to myelin basic protein by inducing a novel, dynamic state of T cell tolerance.
Sarah E Cabbage, Eric S Huseby, Blythe D Sather, Thea Brabb, Denny Liggitt

J Immunol· January 2007

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Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors.
Ryan M Teague, Blythe D Sather, Jilian A Sacks, Maria Z Huang, Michelle L Dossett

Nat Med· March 2006

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CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function.
Claes Ohlén, Michael Kalos, Laurence E Cheng, Aaron C Shur, Doley J Hong, Blythe D Sather

J Exp Med· June 2002

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