Publications by authors named "Bo F Hansen"

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Glucose-sensitive insulin with attenuation of hypoglycaemia.
Thomas Hoeg-Jensen, Thomas Kruse, Christian L Brand, Jeppe Sturis, Christian Fledelius, Bo F Hansen

Nature· October 2024

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Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Henning Hvid, Christian L Brand, Tina Hummelshøj, Sanne Jensen, Stephan D Bouman, Bo F Hansen

Diabetologia· February 2023

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Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing.
Erica Nishimura, Lone Pridal, Tine Glendorf, Bo Falk Hansen, František Hubálek

BMJ Open Diabetes Res Care· August 2021

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Author Correction: Molecular engineering of safe and efficacious oral basal insulin.
Frantisek Hubálek, Hanne H F Refsgaard, Sanne Gram-Nielsen, Peter Madsen, Erica Nishimura, Bo Falck Hansen

Nat Commun· August 2020

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Molecular engineering of safe and efficacious oral basal insulin.
Frantisek Hubálek, Hanne H F Refsgaard, Sanne Gram-Nielsen, Peter Madsen, Erica Nishimura, Bo Falck Hansen

Nat Commun· July 2020

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Increased insulin receptor binding and increased IGF-1 receptor binding are linked with increased growth of L6hIR cell xenografts in vivo.
Henning Hvid, Tine Glendorf, Jakob Brandt, Rita Slaaby, Anne Lützen, Bo F Hansen

Sci Rep· April 2020

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Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine.
Henning Hvid, Jonas Kildegaard, Kim Kristensen, Trine Porsgaard, Mikkel S Jørgensen, Bo F Hansen

J Diabetes Sci Technol· January 2020

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Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.
Laura Hvidsten Ørstrup, Rita Slaaby, Morten Grønbech Rasch, Nicolaj Rasmussen, Søren Lund, Bo Falck Hansen

J Immunol Methods· February 2019

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Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions.
Henning Hvid, Mikkel S Jørgensen, Niels Blume, Rita Slaaby, Anne Lützen, Bo F Hansen

Diabetologia· November 2018

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A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.
Jenny E Kanter, Farah Kramer, Shelley Barnhart, Jeffrey M Duggan, Masami Shimizu-Albergine, Bo F Hansen

Diabetes· May 2018

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Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function.
Stina Rikke Jensen, Sarah E Wheeler, Henning Hvid, Jonas Ahnfelt-Rønne, Bo Falck Hansen

Endocrinology· August 2017

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Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors.
Stina Rikke Jensen, Erwin M Schoof, Sarah E Wheeler, Henning Hvid, Jonas Ahnfelt-Rønne, Bo Falck Hansen

Endocrinology· August 2017

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A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues.
Ivona Baricevic, David R Jones, Darren L Roberts, Anne Lutzen, Anders Lundby, Bo F Hansen

Carcinogenesis· September 2015

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Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues.
Anders Lundby, Pernille Bolvig, Anne Charlotte Hegelund, Bo F Hansen, Jesper Worm

J Appl Toxicol· July 2015

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Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts.
Henning Hvid, Marie-José Blouin, Elena Birman, Jesper Damgaard, Fritz Poulsen, Bo Falck Hansen

PLoS One· July 2014

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Agonism and antagonism at the insulin receptor.
Louise Knudsen, Bo Falck Hansen, Pia Jensen, Thomas Åskov Pedersen, Kirsten Vestergaard

PLoS One· July 2013

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Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation.
Martin Friedrichsen, Jesper B Birk, Erik A Richter, Rasmus Ribel-Madsen, Christian Pehmøller, Bo Falck Hansen

Am J Physiol Endocrinol Metab· March 2013

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Molecular characterisation of long-acting insulin analogues in comparison with human insulin, IGF-1 and insulin X10.
Bo F Hansen, Tine Glendorf, Anne C Hegelund, Anders Lundby, Anne Lützen

PLoS One· September 2012

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Systematic evaluation of the metabolic to mitogenic potency ratio for B10-substituted insulin analogues.
Tine Glendorf, Louise Knudsen, Carsten E Stidsen, Bo F Hansen, Anne Charlotte Hegelund

PLoS One· August 2012

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Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway.
Henning Hvid, Sarah-Maria Fendt, Marie-José Blouin, Elena Birman, Gregory Voisin, Bo Falck Hansen

Endocr Relat Cancer· August 2012

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Insulin therapy in diabetes and cancer risk: current understanding and implications for future study: proceedings from a meeting of a European Insulin Safety Consensus Panel, convened and sponsored by Novo Nordisk, held Tuesday October 5, 2010 at The Radisson Edwardian Heathrow Hotel, Hayes, Middlesex, UK.
Stephen C L Gough, Cristóbal Belda-Iniesta, Christopher Poole, Matthias Weber, David Russell-Jones, Bo Falck Hansen

Adv Ther· September 2011

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In situ phosphorylation of Akt and ERK1/2 in rat mammary gland, colon, and liver following treatment with human insulin and IGF-1.
Henning Hvid, Johannes J Fels, Rikke K Kirk, Inger Thorup, Henrik E Jensen, Bo F Hansen

Toxicol Pathol· June 2011

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Unique expression pattern of the three insulin receptor family members in the rat mammary gland: dominance of IGF-1R and IRR over the IR, and cyclical IGF-1R expression.
Henning Hvid, Robert Klopfleisch, Sara Vienberg, Bo F Hansen, Inger Thorup

J Appl Toxicol· May 2011

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Structural and biological properties of the Drosophila insulin-like peptide 5 show evolutionary conservation.
Waseem Sajid, Nikolaj Kulahin, Gerd Schluckebier, Ulla Ribel, Hope Rosalind Henderson, Bo Falck Hansen

J Biol Chem· January 2011

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Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin.
Christine Bonnesen, Gitte-Mai Nelander, Bo Falck Hansen, Pia Jensen, Jonas S Krabbe

Cell Biol Toxicol· August 2010

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