Publications by authors named "Bobby Lucero"

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Photoaffinity labeling of protein targets in a complex metazoan: proof-of-concept using a probe for tubulin.
Bobby Lucero, Thibault Alle, Marianna Bufano, Yuemang Yao, Kurt R Brunden

bioRxiv· October 2025

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Structure-Activity Relationship and Target Investigation of Thiophen-2-yl-Pyrimidines against species.
Karol R Francisco, Bobby Lucero, Darius Yohannan, Carmine Varricchio, Anny Lam

bioRxiv· October 2025

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-Cystamine: A Deuterated Cystamine Derivative with Improved Anti-Inflammatory and Anti-Fibrotic Activities in a Murine Model of Fibrosing Steatohepatitis.
Aleksandra Leszczynska, Thibault Alle, Benedikt Kaufmann, Hana Sung, Christian Stoess, Bobby Lucero

ACS Pharmacol Transl Sci· March 2025

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Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and Efficacy.
Lawrence J Liu, Karol R Francisco, Yujie Uli Sun, Mateus Sá Magalhães Serafim, Dilini K Amarasinghe, Bobby Lucero

ACS Infect Dis· December 2024

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Clickable Probes for Pathogen Proteasomes: Synthesis and Applications.
Lawrence J Liu, Bobby Lucero, Cindy Manriquez-Rodriguez, Karol R Francisco, Thaiz R Teixeira

ACS Omega· August 2024

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A small-molecule microtubule-stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
Yuemang Yao, Megan Muench, Thibault Alle, Bin Zhang, Bobby Lucero

Alzheimers Dement· July 2024

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Design, Synthesis, and Evaluation of An Anti-trypanosomal [1,2,4]Triazolo[1,5-a]pyrimidine Probe for Photoaffinity Labeling Studies.
Bobby Lucero, Karol R Francisco, Carmine Varricchio, Lawrence J Liu, Yuemang Yao

ChemMedChem· April 2024

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Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Ludovica Monti, Lawrence J Liu, Carmine Varricchio, Bobby Lucero, Thibault Alle

ChemMedChem· October 2023

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Protein-protein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies.
Bobby Lucero, Karol R Francisco, Lawrence J Liu, Conor R Caffrey, Carlo Ballatore

Trends Pharmacol Sci· July 2023

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Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Ludovica Monti, Lawrence J Liu, Carmine Varricchio, Bobby Lucero, Thibault Alle

bioRxiv· March 2023

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Microtubule-Stabilizing 1,2,4-Triazolo[1,5-]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Thibault Alle, Carmine Varricchio, Yuemang Yao, Bobby Lucero, Goodwell Nzou

J Med Chem· January 2023

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Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies.
Killian Oukoloff, Goodwell Nzou, Carmine Varricchio, Bobby Lucero, Thibault Alle

J Med Chem· January 2021

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1,2,4-Triazolo[1,5-a]pyrimidines in drug design.
Killian Oukoloff, Bobby Lucero, Karol R Francisco, Kurt R Brunden, Carlo Ballatore

Eur J Med Chem· March 2019

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