Publications by authors named "Boon C Low"

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Cell signaling across scales in health and disease.
Victoria Sanz-Moreno, Boon Chuan Low

Curr Opin Cell Biol· December 2025

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The Senescence-Associated Secretory Phenotype constitutes HIF-1α activation but is independent of micronuclei-induced cGas/Sting activation.
Celestine Z Ho, Lin Deng, Remigio Picone, Fieda Abderazzaq, Nicole Flanagan, Boon Chuan Low

Mol Biol Cell· November 2025

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Protocol for AI-assisted quantitative analysis and setup of tumor spheroid invasion into tissue.
Celestine Z Ho, Daniella B Lawther, Christina Bao-Xian Huang, Sriram Bharathkumar, Shi Wei Beh, Boon Chuan Low

STAR Protoc· October 2025

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A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway.
Olivia Xuan Liu, Lester Bocheng Lin, Soumya Bunk, Tiweng Chew, Selwin K Wu, Boon Chuan Low

FEBS J· April 2025

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Coordination of Focal Adhesion Nanoarchitecture and Dynamics in Mechanosensing for Cardiomyoblast Differentiation.
Jingwei Xiao, Jing Wen Ang, Xueying Zhong, Darren Chen Pei Wong, Thivakar T, Boon Chuan Low

ACS Appl Mater Interfaces· January 2025

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Insights into the regulation of CHIP E3 ligase-mediated ubiquitination of neuronal protein BNIP-H.
Srihari Shankar, Yaochen Liu, Nikhil Kumar Tulsian, Boon C Low, Qingsong Lin

PNAS Nexus· December 2024

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Focal adhesions are controlled by microtubules through local contractility regulation.
Julien Aureille, Srinivas S Prabhu, Sam F Barnett, Aaron J Farrugia, Isabelle Arnal, Boon Chuan Low

EMBO J· July 2024

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Genome-Wide CRISPR Screen Identifies an NF2-Adherens Junction Mechanistic Dependency for Cardiac Lineage.
Chang Jie Mick Lee, Matias I Autio, Wenhao Zheng, Yoohyun Song, Shyi Chyi Wang, Boon Chuan Low

Circulation· June 2024

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Structural basis for the distinct roles of non-conserved Pro116 and conserved Tyr124 of BCH domain of yeast p50RhoGAP.
Srihari Shankar, Ti Weng Chew, Vishnu Priyanka Reddy Chichili, Boon Chuan Low, J Sivaraman

Cell Mol Life Sci· May 2024

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Three-dimensional liquid metal-based neuro-interfaces for human hippocampal organoids.
Yan Wu, Jinhao Cheng, Jie Qi, Chen Hang, Ruihua Dong, Boon Chuan Low

Nat Commun· May 2024

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Subcellular Force Imbalance in Actin Bundles Induces Nuclear Repositioning and Durotaxis.
Myeongjun Jun, Yin Loon Lee, Tianxun Zhou, Martina Maric, Brian Burke, Boon Chuan Low

ACS Appl Mater Interfaces· September 2023

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Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance.
Kuan Jiang, Su Bin Lim, Jingwei Xiao, Doorgesh Sharma Jokhun, Menglin Shang, Boon Chuan Low

Adv Sci (Weinh)· August 2023

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CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.
You Heng Chuah, Emmy Xue Yun Tay, Oleg V Grinchuk, Jeehyun Yoon, Jia Feng, Boon Chuan Low

Cell Death Differ· August 2023

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The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration.
Darren Chen Pei Wong, Catherine Qiurong Pan, Shi Yin Er, T Thivakar, Tan Zi Yi Rachel, Boon Chuan Low

Mol Biol Cell· March 2023

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Mutant VPS35-D620N induces motor dysfunction and impairs DAT-mediated dopamine recycling pathway.
Yi Huang, Heng Huang, Leping Zhou, Jiawei Li, Xiang Chen, Boon Chuan Low

Hum Mol Genet· November 2022

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BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation.
Darren Chen Pei Wong, Jingwei Xiao, Ti Weng Chew, Meng Pan, Chang Jie Mick Lee, Boon Chuan Low

Adv Sci (Weinh)· November 2022

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Lung Cancer Induces NK Cell Contractility and Cytotoxicity Through Transcription Factor Nuclear Localization.
Darren Chen Pei Wong, E Hui Clarissa Lee, Junzhi Er, Ivan Yow, Ricky Abdi Gunawan Koean, Boon Chuan Low

Front Cell Dev Biol· May 2022

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A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide.
Akila Surendran, C Forbes Dewey, Boon Chuan Low, Lisa Tucker-Kellogg

BMC Mol Cell Biol· October 2021

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Enhanced tumor cell killing by ultrasound after microtubule depolymerization.
Aditi Singh, Ajay Tijore, Felix Margadant, Chloe Simpson, Deepak Chitkara, Boon Chuan Low

Bioeng Transl Med· September 2021

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Structural basis for p50RhoGAP BCH domain-mediated regulation of Rho inactivation.
Vishnu Priyanka Reddy Chichili, Ti Weng Chew, Srihari Shankar, Shi Yin Er, Cheen Fei Chin, Boon Chuan Low

Proc Natl Acad Sci U S A· May 2021

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Distinct mRNAs in Cancer Extracellular Vesicles Activate Angiogenesis and Alter Transcriptome of Vascular Endothelial Cells.
Pan Zhang, Su Bin Lim, Kuan Jiang, Ti Weng Chew, Boon Chuan Low

Cancers (Basel)· April 2021

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Common and Unique Transcription Signatures of YAP and TAZ in Gastric Cancer Cells.
Yaelim Lee, Megan Finch-Edmondson, Hamizah Cognart, Bowen Zhu, Haiwei Song, Boon Chuan Low

Cancers (Basel)· December 2020

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Bile canaliculi contract autonomously by releasing calcium into hepatocytes via mechanosensitive calcium channel.
Kapish Gupta, Inn Chuan Ng, Gowri Manohari Balachander, Binh P Nguyen, Lisa Tucker-Kellogg, Boon Chuan Low

Biomaterials· November 2020

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Rab5a activates IRS1 to coordinate IGF-AKT-mTOR signaling and myoblast differentiation during muscle regeneration.
Xiao Xia Cong, Xiu Kui Gao, Xi Sheng Rao, Jie Wen, Xiao Ceng Liu, Boon Chuan Low

Cell Death Differ· August 2020

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BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation.
Meng Pan, Ti Weng Chew, Darren Chen Pei Wong, Jingwei Xiao, Hui Ting Ong, Boon Chuan Low

Sci Adv· July 2020

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