Publications by authors named "Boopathy Ramakrishnan"

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Characterization of an Antibody Recognizing the Conserved Inner Core of Lipopolysaccharides.
Stefano Elli, Anna Alekseeva, Boopathy Ramakrishnan, Tyree Koch, Andrew Wollacott

Biochemistry· November 2020

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VIS832, a novel CD138-targeting monoclonal antibody, potently induces killing of human multiple myeloma and further synergizes with IMiDs or bortezomib in vitro and in vivo.
Tengteng Yu, Bharat Chaganty, Liang Lin, Lijie Xing, Boopathy Ramakrishnan

Blood Cancer J· November 2020

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Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data.
Andrew M Wollacott, Luke N Robinson, Boopathy Ramakrishnan, Hamid Tissire, Karthik Viswanathan

J Mol Recognit· July 2019

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A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy.
James R Myette, Toshiki Kano, Hitoshi Suzuki, Susan E Sloan, Kristy J Szretter, Boopathy Ramakrishnan

Kidney Int· July 2019

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Extending human IgG half-life using structure-guided design.
Brian J Booth, Boopathy Ramakrishnan, Kristin Narayan, Andrew M Wollacott, Gregory J Babcock

MAbs· October 2018

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A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.
Boopathy Ramakrishnan, Karthik Viswanathan, Kannan Tharakaraman, Vlado Dančík, Rahul Raman

Trends Microbiol· December 2016

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Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugar.
Zhongyu Zhu, Boopathy Ramakrishnan, Jinyu Li, Yanping Wang, Yang Feng

MAbs· August 2015

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Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.
Luke N Robinson, Kannan Tharakaraman, Kirk J Rowley, Vivian V Costa, Kuan Rong Chan, Boopathy Ramakrishnan

Cell· July 2015

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In vitro folding of β-1,4galactosyltransferase and polypeptide-α-N-acetylgalactosaminyltransferase from the inclusion bodies.
Boopathy Ramakrishnan, Pradman K Qasba

Methods Mol Biol· January 2014

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Investigations on β1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate.
Boopathy Ramakrishnan, Anthony J Moncrief, Tyler A Davis, Lisa A Holland, Pradman K Qasba

Glycoconj J· December 2013

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Crystal structures of β-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
Yuko Tsutsui, Boopathy Ramakrishnan, Pradman K Qasba

J Biol Chem· November 2013

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Use of novel mutant galactosyltransferase for the bioconjugation of terminal N-acetylglucosamine (GlcNAc) residues on live cell surface.
Natalia Mercer, Boopathy Ramakrishnan, Elizabeth Boeggeman, Luke Verdi, Pradman K Qasba

Bioconjug Chem· January 2013

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Binding of N-acetylglucosamine (GlcNAc) β1-6-branched oligosaccharide acceptors to β4-galactosyltransferase I reveals a new ligand binding mode.
Boopathy Ramakrishnan, Elizabeth Boeggeman, Pradman K Qasba

J Biol Chem· August 2012

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The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2.
Marta Pasek, Boopathy Ramakrishnan, Elizabeth Boeggeman, Natalia Mercer, Andres E Dulcey

Glycobiology· March 2012

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Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.
Natalia Mercer, Boopathy Ramakrishnan, Elizabeth Boeggeman, Pradman K Qasba

PLoS One· February 2012

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Bioconjugation using mutant glycosyltransferases for the site-specific labeling of biomolecules with sugars carrying chemical handles.
Boopathy Ramakrishnan, Elizabeth Boeggeman, Marta Pasek, Pradman K Qasba

Methods Mol Biol· September 2011

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Structure-based evolutionary relationship of glycosyltransferases: a case study of vertebrate β1,4-galactosyltransferase, invertebrate β1,4-N-acetylgalactosaminyltransferase and α-polypeptidyl-N-acetylgalactosaminyltransferase.
Boopathy Ramakrishnan, Pradman K Qasba

Curr Opin Struct Biol· October 2010

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Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
Boopathy Ramakrishnan, Pradman K Qasba

J Biol Chem· May 2010

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Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli.
Marta Pasek, Elizabeth Boeggeman, Boopathy Ramakrishnan, Pradman K Qasba

Biochem Biophys Res Commun· April 2010

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Multiple site-specific in vitro labeling of single-chain antibody.
Boopathy Ramakrishnan, Elizabeth Boeggeman, Maria Manzoni, Zhongyu Zhu, Kristin Loomis

Bioconjug Chem· July 2009

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Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection.
Elizabeth Boeggeman, Boopathy Ramakrishnan, Marta Pasek, Maria Manzoni, Anu Puri

Bioconjug Chem· June 2009

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Bioconjugation and detection of lactosamine moiety using alpha1,3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle.
Marta Pasek, Boopathy Ramakrishnan, Elizabeth Boeggeman, Maria Manzoni, Timothy J Waybright

Bioconjug Chem· March 2009

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Iterative cluster-NMA: A tool for generating conformational transitions in proteins.
Adam D Schuyler, Robert L Jernigan, Pradman K Qasba, Boopathy Ramakrishnan, Gregory S Chirikjian

Proteins· February 2009

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Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis.
Jillian R Brown, Feng Yang, Anjana Sinha, Boopathy Ramakrishnan, Yitzhak Tor

J Biol Chem· February 2009

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Site-specific linking of biomolecules via glycan residues using glycosyltransferases.
Pradman K Qasba, Elizabeth Boeggeman, Boopathy Ramakrishnan

Biotechnol Prog· November 2008

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