Publications by authors named "Boris Kantor"

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Trends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease.
Boris Kantor, Bernadette O'Donovan, Ornit Chiba-Falek

Mol Ther Nucleic Acids· September 2025

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-targeted epigenome therapy for Parkinson's disease alleviates pathological and behavioral perturbations in a mouse model.
Bernadette O'Donovan, Joseph Rittiner, Suraj Upadhya, Dellila Hodgson, Boris Kantor

bioRxiv· June 2025

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The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders.
Boris Kantor, Bernadette O'Donovan, Joseph Rittiner, Dellila Hodgson, Nicholas Lindner

Nat Commun· August 2024

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All-in-one AAV-delivered epigenome-editing platform: and therapeutic implications for neurodegenerative disorders.
Boris Kantor, Bernadette Odonovan, Joseph Rittiner, Dellila Hodgson, Nicholas Lindner

bioRxiv· May 2024

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Neuronal-type-specific epigenome editing to decrease expression: Implications for precision medicine in synucleinopathies.
Zhiguo Sun, Boris Kantor, Ornit Chiba-Falek

Mol Ther Nucleic Acids· March 2024

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Therapeutic modulation of gene expression in the disease state: Treatment strategies and approaches for the development of next-generation of the epigenetic drugs.
Joseph Rittiner, Mohanapriya Cumaran, Sahil Malhotra, Boris Kantor

Front Bioeng Biotechnol· October 2022

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Lentiviral Vectors for Delivery of Gene-Editing Systems Based on CRISPR/Cas: Current State and Perspectives.
Wendy Dong, Boris Kantor

Viruses· July 2021

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Adeno-Associated Virus-Mediated Gene Therapy in the Mashlool, , Mouse Model of Alternating Hemiplegia of Childhood.
Arsen S Hunanyan, Boris Kantor, Ram S Puranam, Courtney Elliott, Angela McCall

Hum Gene Ther· April 2021

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Cell-Type Specific Changes in DNA Methylation of Intron 1 in Synucleinopathy Brains.
Jeffrey Gu, Julio Barrera, Young Yun, Susan K Murphy, Thomas G Beach, Boris Kantor

Front Neurosci· April 2021

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The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models.
Gabriella MacDougall, Logan Y Brown, Boris Kantor, Ornit Chiba-Falek

Mol Ther· March 2021

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: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer's.
Anna Yang, Boris Kantor, Ornit Chiba-Falek

Int J Mol Sci· January 2021

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An Improved Protocol for the Production of Lentiviral Vectors.
Logan Y Brown, Wendy Dong, Boris Kantor

STAR Protoc· December 2020

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The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations.
Vivian Chen, Malik Moncalvo, Dominic Tringali, Lidia Tagliafierro, Ahila Shriskanda, Boris Kantor

Hum Mol Genet· November 2020

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Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer's disease.
Misha Angrist, Anna Yang, Boris Kantor, Ornit Chiba-Falek

Life Sci Soc Policy· October 2020

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Viral-Mediated Gene Replacement Therapy in the Developing Central Nervous System: Current Status and Future Directions.
Julie Uchitel, Boris Kantor, Edward C Smith, Mohamad A Mikati

Pediatr Neurol· September 2020

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Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases.
Joseph Edward Rittiner, Malik Moncalvo, Ornit Chiba-Falek, Boris Kantor

Front Mol Neurosci· August 2020

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Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models.
Lidia Tagliafierro, Ekaterina Ilich, Malik Moncalvo, Jeffrey Gu, Ahila Sriskanda, Boris Kantor

J Vis Exp· March 2019

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Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD.
Boris Kantor, Lidia Tagliafierro, Jeffrey Gu, Madison E Zamora, Ekaterina Ilich

Mol Ther· November 2018

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Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Allison M Manuel, Michael D Walla, Adam Faccenda, Stephanie L Martin, Ross M Tanis, Boris Kantor

Antioxid Redox Signal· December 2017

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A Protocol for the Production of Integrase-deficient Lentiviral Vectors for CRISPR/Cas9-mediated Gene Knockout in Dividing Cells.
Sriram Vijayraghavan, Boris Kantor

J Vis Exp· December 2017

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Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing.
Pavel I Ortinski, Bernadette O'Donovan, Xiaoyu Dong, Boris Kantor

Mol Ther Methods Clin Dev· June 2017

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Clinical applications involving CNS gene transfer.
Boris Kantor, Thomas McCown, Paola Leone, Steven J Gray

Adv Genet· June 2015

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Methods for gene transfer to the central nervous system.
Boris Kantor, Rachel M Bailey, Keon Wimberly, Sahana N Kalburgi, Steven J Gray

Adv Genet· June 2015

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Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer.
Mark A Titus, Brian Zeithaml, Boris Kantor, Xiangping Li, Karin Haack

PLoS One· June 2012

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AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.
Jarrod S Johnson, Martina Gentzsch, Liqun Zhang, Carla M P Ribeiro, Boris Kantor

PLoS Pathog· May 2011

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