Publications by authors named "Boris Lin"

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CNS Protective Effect of Selpercatinib in First-Line Fusion-Positive Advanced Non-Small Cell Lung Cancer.
Maurice Pérol, Benjamin J Solomon, Koichi Goto, Keunchil Park, Ernest Nadal, Boris K Lin

J Clin Oncol· July 2024

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Retraction: Ku86 Variant Expression and Function in Multiple Myeloma Cells Is Associated with Increased Sensitivity to DNA Damage.
Yu-Tzu Tai, Gerrard Teoh, Boris Lin, Faith E Davies, Dharminder Chauhan

J Immunol· April 2024

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Phase 3 Trial of Selpercatinib in Advanced -Mutant Medullary Thyroid Cancer.
Julien Hadoux, Rossella Elisei, Marcia S Brose, Ana O Hoff, Bruce G Robinson, Yan Lin, Boris Lin

N Engl J Med· November 2023

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First-Line Selpercatinib or Chemotherapy and Pembrolizumab in Fusion-Positive NSCLC.
Caicun Zhou, Benjamin Solomon, Herbert H Loong, Keunchil Park, Maurice Pérol, Nalin Payakachat, A Bence Lin, Boris K Lin

N Engl J Med· November 2023

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Phase Ib/II Study of Enzalutamide with Samotolisib (LY3023414) or Placebo in Patients with Metastatic Castration-Resistant Prostate Cancer.
Christopher J Sweeney, Ivor J Percent, Sunil Babu, Jennifer L Cultrera, Bryan A Mehlhaff, Boris Kin Lin

Clin Cancer Res· June 2022

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Phase III study of selpercatinib versus chemotherapy ± pembrolizumab in untreated positive non-small-cell lung cancer.
Benjamin J Solomon, Cai Cun Zhou, Alexander Drilon, Keunchil Park, Jürgen Wolf, Aimee Bence Lin, Boris K Lin

Future Oncol· March 2021

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LY2495655, an antimyostatin antibody, in pancreatic cancer: a randomized, phase 2 trial.
Talia Golan, Ravit Geva, Donald Richards, Srinivasan Madhusudan, Boris Kin Lin

J Cachexia Sarcopenia Muscle· October 2018

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Analytical Characterization of an Enzyme-Linked Immunosorbent Assay for the Measurement of Transforming Growth Factor β1 in Human Plasma.
Brendan M Giles, Timothy T Underwood, Karim A Benhadji, Diana K S Nelson, Lisa M Grobeck, Boris Lin

J Appl Lab Med· September 2018

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A randomized, phase 2 study of R-CHOP plus enzastaurin vs R-CHOP in patients with intermediate- or high-risk diffuse large B-cell lymphoma.
John D Hainsworth, Edward R Arrowsmith, Michael McCleod, Eric D Hsi, Oday Hamid, Boris K Lin

Leuk Lymphoma· October 2016

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Randomized, Double-Blind, Phase III Trial of Enzastaurin Versus Placebo in Patients Achieving Remission After First-Line Therapy for High-Risk Diffuse Large B-Cell Lymphoma.
Michael Crump, Sirpa Leppä, Luis Fayad, Je Jung Lee, Alice Di Rocco, Boris Lin

J Clin Oncol· July 2016

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Myostatin Neutralization Results in Preservation of Muscle Mass and Strength in Preclinical Models of Tumor-Induced Muscle Wasting.
Rosamund C Smith, Martin S Cramer, Pamela J Mitchell, Andrew Capen, Lysiane Huber, Boris K Lin

Mol Cancer Ther· July 2015

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Open-label, single-arm, phase II study of enzastaurin in patients with follicular lymphoma.
Lee Schwartzberg, Robert Hermann, Ian Flinn, Douglas Flora, Eric D Hsi, Boris K Lin, Martin Dreyling

Br J Haematol· July 2014

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Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders.
Rosamund C Smith, Boris K Lin

Curr Opin Support Palliat Care· December 2013

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A multicenter, open-label, noncomparative screening study of enzastaurin in adult patients with non-Hodgkin lymphomas.
Cecily J Forsyth, David Gomez-Almaguer, Johnny F C Camargo, Paul E Eliadis, Erick Crespo-Solis, Boris Lin

Clin Lymphoma Myeloma Leuk· August 2013

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Multicenter phase II trial of enzastaurin in patients with relapsed or refractory advanced cutaneous T-cell lymphoma.
Christiane Querfeld, Timothy M Kuzel, Youn H Kim, Pierluigi Porcu, Madeleine Duvic, Boris Lin

Leuk Lymphoma· August 2011

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A phase I study of pemetrexed in patients with relapsed or refractory acute leukemia.
Isam Abdel-Karim, William K Plunkett, Susan O'Brien, Francis Giles, Deborah Thomas, Boris K Lin

Invest New Drugs· April 2011

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Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
Marc S Raab, Iris Breitkreutz, Giovanni Tonon, Jing Zhang, Patrick J Hayden, Boris K Lin

Blood· February 2009

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Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl).
Klaus Podar, Marc S Raab, Jing Zhang, Douglas McMillin, Iris Breitkreutz, Boris K Lin

Blood· February 2007

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Retrospective analysis of protein kinase C-beta (PKC-beta) expression in lymphoid malignancies and its association with survival in diffuse large B-cell lymphomas.
Shuyu Li, Mark Phong, Michael Lahn, Leslie Brail, Susan Sutton, Boris K Lin

Biol Direct· February 2007

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A randomized phase III study of gemcitabine, dexamethasone, and cisplatin versus dexamethasone, cytarabine, and cisplatin as salvage chemotherapy followed by posttransplantation rituximab maintenance therapy versus observation for treatment of aggressive B-Cell and T-Cell non-Hodgkin's lymphoma.
Michael Crump, Lois Shepherd, Boris Lin

Clin Lymphoma· June 2005

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Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo.
Boris Lin, Laurence Catley, Richard LeBlanc, Constantine Mitsiades, Renate Burger

Blood· January 2005

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CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
Yu-Tzu Tai, Klaus Podar, Nicholas Mitsiades, Boris Lin, Constantine Mitsiades

Blood· April 2003

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The vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment.
Boris Lin, Klaus Podar, Deepak Gupta, Yu-Tzu Tai, Sigui Li

Cancer Res· September 2002

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beta-lapachone, a novel plant product, overcomes drug resistance in human multiple myeloma cells.
Deepak Gupta, Klaus Podar, Yu Tzu Tai, Boris Lin, Teru Hideshima

Exp Hematol· July 2002

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Translocation of Ku86/Ku70 to the multiple myeloma cell membrane: functional implications.
Yu-Tzu Tai, Klaus Podar, Stine-Kathrein Kraeft, Fengfei Wang, Gloria Young, Boris Lin

Exp Hematol· March 2002

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