Publications by authors named "Brad Rothberg"

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Lipid-mediated hydrophobic gating in the BK potassium channel.
Lucia Coronel, Giovanni Di Muccio, Brad S Rothberg, Alberto Giacomello, Vincenzo Carnevale

Nat Commun· August 2025

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Lipid-mediated hydrophobic gating in the BK potassium channel.
Lucia Coronel, Giovanni Di Muccio, Brad Rothberg, Alberto Giacomello, Vincenzo Carnevale

ArXiv· May 2024

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Interactions between selectivity filter and pore helix control filter gating in the MthK channel.
Wojciech Kopec, Andrew S Thomson, Bert L de Groot, Brad S Rothberg

J Gen Physiol· August 2023

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A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Qian Guo, Mingyang Xin, Qingchun Lu, Dechun Feng, Vicky Yang, Brad S Rothberg

Theranostics· May 2023

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Interrogating the gating motions of the NaK channel.
Brad S Rothberg

J Gen Physiol· December 2022

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Knockdown of lncRNA TP53TG1 Enhances the Efficacy of Sorafenib in Human Hepatocellular Carcinoma Cells.
Qingchun Lu, Mingyang Xin, Qian Guo, Brad S Rothberg, Ana M Gamero

Noncoding RNA· August 2022

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State-dependent inhibition of BK channels by the opioid agonist loperamide.
Alexandre G Vouga, Michael E Rockman, Jiusheng Yan, Marlene A Jacobson, Brad S Rothberg

J Gen Physiol· September 2021

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Gating and calcium-sensing mechanisms of TRPA1 channels revealed.
Sebastian E Brauchi, Brad S Rothberg

Cell Calcium· November 2020

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Polyamine blockade and binding energetics in the MthK potassium channel.
Antonio Suma, Daniele Granata, Andrew S Thomson, Vincenzo Carnevale, Brad S Rothberg

J Gen Physiol· July 2020

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Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021.
Michael E Rockman, Alexandre G Vouga, Brad S Rothberg

J Gen Physiol· June 2020

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An international gathering of physiologists in Valparaiso, Chile.
Merritt C Maduke, Brad S Rothberg

J Gen Physiol· June 2020

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Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling.
Wojciech Kopec, Brad S Rothberg, Bert L de Groot

Nat Commun· November 2019

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Charge of the Proton Channel.
Brad S Rothberg

Biophys J· June 2018

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Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.
Rebecca J Howard, Vincenzo Carnevale, Lucie Delemotte, Ute A Hellmich, Brad S Rothberg

Biochim Biophys Acta Biomembr· April 2018

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Molecular determinants of Ca sensitivity at the intersubunit interface of the BK channel gating ring.
Qin Li, Yingxin Li, Hua Wei, Hao-Min Pan, Alexandre G Vouga, Brad S Rothberg

Sci Rep· January 2018

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Understanding the conformational motions of RCK gating rings.
Teresa Giraldez, Brad S Rothberg

J Gen Physiol· April 2017

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A slick, slack pathway through the pore.
Brad S Rothberg

J Physiol· April 2017

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The STIM1-binding site nexus remotely controls Orai1 channel gating.
Yandong Zhou, Xiangyu Cai, Natalia A Loktionova, Xianming Wang, Robert M Nwokonko, Brad S Rothberg

Nat Commun· December 2016

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Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Xizhuo Wang, Youjun Wang, Yandong Zhou, Eunan Hendron, Salvatore Mancarella, Brad S Rothberg

Nat Commun· March 2016

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Sterol hindrance of Orai activation.
Robert Hooper, Brad S Rothberg, Jonathan Soboloff

Sci Signal· March 2016

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STIM1 dimers undergo unimolecular coupling to activate Orai1 channels.
Yandong Zhou, Xizhuo Wang, Xianming Wang, Natalia A Loktionova, Xiangyu Cai, Brad S Rothberg

Nat Commun· September 2015

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An old probe sheds new light on BK channel pore structure.
Owen B McManus, Brad S Rothberg

J Gen Physiol· December 2014

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Neuronal STIMulation at rest.
Robert Hooper, Brad S Rothberg, Jonathan Soboloff

Sci Signal· July 2014

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Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain.
Frank J Smith, Victor P T Pau, Gino Cingolani, Brad S Rothberg

Nat Commun· May 2014

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Initial steps of inactivation at the K+ channel selectivity filter.
Andrew S Thomson, Florian T Heer, Frank J Smith, Eunan Hendron, Simon Bernèche, Brad S Rothberg

Proc Natl Acad Sci U S A· April 2014

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