Publications by authors named "Brandon Metge"

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Nucleolar proteomics identifies S100A16 as a key nucleolar protein driving breast cancer metastasis.
Brandon J Metge, Mohamed H Elbahoty, Amr R Elhamamsy, Anne E Popple, Bhavya Papineni

Cell Death Dis· August 2025

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Hypoxic stress incites HIF1α-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I.
Amr Elhamamsy, Brandon J Metge, Courtney A Swain, Mohamed H Elbahoty, Dominique C Hinshaw

Nat Commun· August 2025

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Ribosomal RNA Biosynthesis Functionally Programs Tumor-Associated Macrophages to Support Breast Cancer Progression.
Brandon J Metge, Li'an Williams, Courtney A Swain, Dominique C Hinshaw, Amr R Elhamamsy

Cancer Res· April 2025

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Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer.
Brandon J Metge, Heba Allah M Alsheikh, Sarah C Kammerud, Dongquan Chen, Devika Das

Cell Death Dis· May 2024

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Ribosome biosynthesis and Hedgehog activity are cooperative actionable signaling mechanisms in breast cancer following radiotherapy.
Brandon J Metge, Heba A Alsheikh, Dongquan Chen, Amr R Elhamamsy, Dominique C Hinshaw

NPJ Precis Oncol· June 2023

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Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer.
Dominique C Hinshaw, Gloria A Benavides, Brandon J Metge, Courtney A Swain, Sarah C Kammerud

Cancer Immunol Res· May 2023

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Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance.
Amr R Elhamamsy, Brandon J Metge, Heba A Alsheikh, Lalita A Shevde, Rajeev S Samant

Cancer Res· July 2022

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Novel role of the dietary flavonoid fisetin in suppressing rRNA biogenesis.
Sarah C Kammerud, Brandon J Metge, Amr R Elhamamsy, Shannon E Weeks, Heba A Alsheikh

Lab Invest· November 2021

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Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages.
Dominique C Hinshaw, Ann Hanna, Tshering Lama-Sherpa, Brandon Metge, Sarah C Kammerud

Cancer Res· November 2021

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Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding.
Heba Allah M Alsheikh, Brandon J Metge, Chae-Myeong Ha, Dominique C Hinshaw, Mateus S V Mota

Cancer Lett· October 2021

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Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors.
Heba Allah M Alsheikh, Brandon J Metge, Hawley C Pruitt, Sarah C Kammerud, Dongquan Chen

Oncogenesis· June 2021

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Merlin deficiency alters the redox management program in breast cancer.
Mateus Mota, Brandon J Metge, Dominique C Hinshaw, Heba A Alsheikh, Dongquan Chen

Mol Oncol· April 2021

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Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer.
Shannon E Weeks, Sarah C Kammerud, Brandon J Metge, Heba A AlSheikh, David A Schneider

Cell Death Dis· March 2021

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Hypoxia re-programs 2'-O-Me modifications on ribosomal RNA.
Brandon J Metge, Sarah C Kammerud, Hawley C Pruitt, Lalita A Shevde, Rajeev S Samant

iScience· January 2021

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Hedgehog signaling enables repair of ribosomal DNA double-strand breaks.
Tshering D Lama-Sherpa, Victor T G Lin, Brandon J Metge, Shannon E Weeks, Dongquan Chen

Nucleic Acids Res· October 2020

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The nucleolus: a central response hub for the stressors that drive cancer progression.
Shannon E Weeks, Brandon J Metge, Rajeev S Samant

Cell Mol Life Sci· November 2019

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O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity.
Shamik Das, Sarah K Bailey, Brandon J Metge, Ann Hanna, Dominique C Hinshaw

Lab Invest· February 2019

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Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer.
Ann Hanna, Brandon J Metge, Sarah K Bailey, Dongquan Chen, Darshan S Chandrashekar

Oncoimmunology· December 2018

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Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors.
Hawley C Pruitt, Brandon J Metge, Shannon E Weeks, Dongquan Chen, Shi Wei

Oncogene· March 2018

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Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer.
K Adam Morrow, Shamik Das, Erhong Meng, Mitchell E Menezes, Sarah K Bailey, Brandon J Metge

Oncotarget· April 2016

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N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells.
Brandon J Metge, Aparna Mitra, Dongquan Chen, Lalita A Shevde, Rajeev S Samant

Sci Rep· July 2015

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microRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancer.
Jack W Rostas, Hawley C Pruitt, Brandon J Metge, Aparna Mitra, Sarah K Bailey

Mol Cancer· August 2014

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Effect of niclosamide on basal-like breast cancers.
Angelina I Londoño-Joshi, Rebecca C Arend, Laura Aristizabal, Wenyan Lu, Rajeev S Samant, Brandon J Metge

Mol Cancer Ther· April 2014

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Loss of tumor suppressor Merlin in advanced breast cancer is due to post-translational regulation.
K Adam Morrow, Shamik Das, Brandon J Metge, Keqiang Ye, Madhuri S Mulekar

J Biol Chem· November 2011

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Elevated osteopontin levels in metastatic melanoma correlate with epigenetic silencing of breast cancer metastasis suppressor 1.
Brandon J Metge, Suhu Liu, Adam I Riker, Oystein Fodstad, Rajeev S Samant

Oncology· April 2010

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