Publications by authors named "Brandy Verhalen"

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Rapid Quantitation of Various Therapeutic Monoclonal Antibodies Using Membranes with Fc-Specific Ligands.
Junyan Yang, Raluca Ostafe, Christopher J Welch, Brandy Verhalen, Ivan L Budyak

Anal Chem· June 2023

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AAV-Mediated Artificial miRNA Reduces Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models.
Emrah Gumusgoz, Sahba Kasiri, Dikran R Guisso, Jun Wu, Matthew Dear, Brandy Verhalen

Neurotherapeutics· April 2022

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BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation.
Joshua L Justice, Jason M Needham, Brandy Verhalen, Mengxi Jiang, Sunnie R Thompson

J Virol· April 2022

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EPM2A in-frame deletion slows neurological decline in Lafora Disease.
Lysa Boissé Lomax, Brandy Verhalen, Berge A Minassian

Seizure· October 2021

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Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease.
Lori Israelian, Silvia Nitschke, Peixiang Wang, Xiaochu Zhao, Ami M Perri, Brandy Verhalen

J Neurochem· June 2021

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Targeting Gys1 with AAV-SaCas9 Decreases Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models.
Emrah Gumusgoz, Dikran R Guisso, Sahba Kasiri, Jun Wu, Matthew Dear, Brandy Verhalen

Neurotherapeutics· April 2021

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Polyomavirus T Antigen Induces Expression Using an LXCXE-Dependent and TP53-Independent Mechanism.
Gabriel J Starrett, Artur A Serebrenik, Pieter A Roelofs, Jennifer L McCann, Brandy Verhalen

mBio· February 2019

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Lafora Disease: A Review of Molecular Mechanisms and Pathology.
Brandy Verhalen, Susan Arnold, Berge A Minassian

Neuropediatrics· December 2018

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Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein.
Brandy Verhalen, Reza Dastvan, Sundarapandian Thangapandian, Yelena Peskova, Hanane A Koteiche

Nature· March 2017

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Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses.
Brandy Verhalen, Gabriel J Starrett, Reuben S Harris, Mengxi Jiang

J Virol· July 2016

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Quantitative Proteomic Analysis of Enriched Nuclear Fractions from BK Polyomavirus-Infected Primary Renal Proximal Tubule Epithelial Cells.
Joshua L Justice, Brandy Verhalen, Ranjit Kumar, Elliot J Lefkowitz, Michael J Imperiale

J Proteome Res· October 2015

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Viral DNA replication-dependent DNA damage response activation during BK polyomavirus infection.
Brandy Verhalen, Joshua L Justice, Michael J Imperiale, Mengxi Jiang

J Virol· May 2015

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Polyomavirus interaction with the DNA damage response.
Joshua L Justice, Brandy Verhalen, Mengxi Jiang

Virol Sin· April 2015

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Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter.
Smriti Mishra, Brandy Verhalen, Richard A Stein, Po-Chao Wen, Emad Tajkhorshid

Elife· May 2014

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Analyzing conformational dynamics of single P-glycoprotein transporters by Förster resonance energy transfer using hidden Markov models.
Nawid Zarrabi, Stefan Ernst, Brandy Verhalen, Stephan Wilkens, Michael Börsch

Methods· March 2014

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On the origin of large flexibility of P-glycoprotein in the inward-facing state.
Po-Chao Wen, Brandy Verhalen, Stephan Wilkens, Hassane S Mchaourab, Emad Tajkhorshid

J Biol Chem· June 2013

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Dynamic ligand-induced conformational rearrangements in P-glycoprotein as probed by fluorescence resonance energy transfer spectroscopy.
Brandy Verhalen, Stefan Ernst, Michael Börsch, Stephan Wilkens

J Biol Chem· January 2012

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P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends.
Brandy Verhalen, Stephan Wilkens

J Biol Chem· March 2011

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