Publications by authors named "Braxton D Mitchell"

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Exonic Variation and Its Clinical Impact in 7221 Old Order Amish.
Braxton D Mitchell, Ebuka Onyenobi, Joshua P Lewis, Brady Gaynor, James A Perry

Am J Med Genet A· December 2025

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Attitudes toward returning pathogenic variant and uptake of cascade screening in the Amish.
Elizabeth A Streeten, Yue Guan, Kathleen A Ryan, Melanie Daue, Toni I Pollin, Braxton D Mitchell

Genet Med Open· November 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Ruth E Mitchell, Braxton D Mitchell, Paul Mitchell

Nat Med· September 2025

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Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Braxton D Mitchell

Genome Biol· September 2025

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Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding.
Rachel K Friedman, Adam S Heath, Jennifer E Huffman, James T Baker, Natalie R Hasbani, Braxton D Mitchell

J Thromb Haemost· August 2025

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Correction to: Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations.
Ebuka Onyenobi, Michael Zhong, Opeyemi Soremekun, Abram Kamiza, Romuald Boua, Braxton D Mitchell

Circ Genom Precis Med· August 2025

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Multi-phase, multi-ethnic GWAS uncovers putative loci in predisposition to elite sprint and power performance, health and disease.
Guan Wang, Noriyuki Fuku, Eri Miyamoto-Mikami, Masashi Tanaka, Motohiko Miyachi, Braxton D Mitchell

Biol Sport· July 2025

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Functional vs Structural Cortical Deficit Pattern Biomarkers for Major Depressive Disorder.
Peter Kochunov, Bhim M Adhikari, David Keator, Daniel Amen, Si Gao, Braxton D Mitchell

JAMA Psychiatry· June 2025

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Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations.
Ebuka Onyenobi, Michael Zhong, Opeyemi Soremekun, Abram Kamiza, Romuald Boua, Braxton D Mitchell

Circ Genom Precis Med· June 2025

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Translational genomics of osteoarthritis in 1,962,069 individuals.
Konstantinos Hatzikotoulas, Lorraine Southam, Lilja Stefansdottir, Cindy G Boer, Merry-Lynn McDonald, Braxton D Mitchell

Nature· May 2025

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Adherence to life's essential 8 is associated with delayed white matter aging.
Li Feng, Zhenyao Ye, Yezhi Pan, Rozalina G McCoy, Braxton D Mitchell

EBioMedicine· May 2025

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Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants.
Yao Hu, Jeff Haessler, Jessica I Lundin, Burcu F Darst, Eric A Whitsel, Braxton D Mitchell

Clin Epigenetics· April 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Braxton D Mitchell

Nat Commun· April 2025

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Multi-ancestry whole genome sequencing analysis of lean body mass.
Xiaoyu Zhang, Kuan-Jui Su, Bodhisattwa Banerjee, Ittai Eres, Yi-Hsiang Hsu, Braxton D Mitchell

Genome Biol· April 2025

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Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness.
Devendra Meena, Jian Huang, Marjan Zare, Natalie R Hasbani, Boua Palwendé Romuald, Braxton D Mitchell

medRxiv· April 2025

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Impact of Conventional Stroke Risk Factors on Early- and Late-Onset Ischemic Stroke: A Mendelian Randomization Study.
Kevin T K Nguyen, Huichun Xu, Brady J Gaynor, Patrick F McArdle, Timothy D O'Connor, Braxton D Mitchell

Stroke· March 2025

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Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li, Braxton D Mitchell

Genome Med· March 2025

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Mitchell J Machiela, Braxton D Mitchell

Am J Hum Genet· February 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Braxton D Mitchell

Nat Comput Sci· February 2025

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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants.
Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, Ketrin Gjoni, Adam S Heath, Braxton D Mitchell

J Am Heart Assoc· February 2025

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The association of SUR1 polymorphisms with acute infarct size: The MRI-GENIE study.
Arlinda Deng, Huichun Xu, Brady J Gaynor, John W Cole, Anne-Katrin Giese, Braxton D Mitchell

J Stroke Cerebrovasc Dis· January 2025

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Can Genetics Improve Prediction of Poststroke Epilepsy?
Alain Lekoubou, Braxton D Mitchell

Stroke· December 2024

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Accelerating Heritability, Genetic Correlation, and Genome-Wide Association Imaging Genetic Analyses in Complex Pedigrees.
Brian Donohue, Si Gao, Thomas E Nichols, Bhim M Adhikari, Yizhou Ma, Braxton D Mitchell

Hum Brain Mapp· December 2024

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Adherence to Life's Essential 8 is associated with delayed white matter aging.
Li Feng, Zhenyao Ye, Yezhi Pan, Rozalina G McCoy, Braxton D Mitchell

medRxiv· December 2024

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Randomized evaluation of the loss-of-function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics.
Joshua P Lewis, Kathleen A Ryan, Elizabeth A Streeten, Hilary B Whitlatch, Melanie Daue, Braxton D Mitchell

Clin Transl Sci· November 2024

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