Publications by authors named "BreAnne Mackenzie"

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Inhaled LTI-03 for Idiopathic Pulmonary Fibrosis: A Randomized Dose Escalation Study.
Philip L Molyneaux, Nikhil A Hirani, Collin C K Chia, Tejaswini Kulkarni, Tanzira Zaman, BreAnne MacKenzie

medRxiv· October 2025

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LTI-03 peptide demonstrates anti-fibrotic activity in lung slices from patients with IPF.
BreAnne MacKenzie, Poornima Mahavadi, Yago Amigo Pinho Jannini-Sa, Brecht Creyns, Ana Lucia Coelho

iScience· September 2025

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Caveolin Scaffolding Domain (CSD) Peptide LTI-2355 Modulates the Phagocytic and Synthetic Activity of Lung-Derived Myeloid Cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-Acute Sequelae of COVID Fibrosis (PASC-F).
Brecht Creyns, BreAnne MacKenzie, Yago Amigo Pinho Jannini Sa, Ana Lucia Coelho, Dale Christensen

Biomedicines· March 2025

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Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis.
BreAnne MacKenzie, Poornima Mahavadi, Yago Amigo Pinho Jannini-Sa, Brecht Creyns, Ana Lucia Coelho

bioRxiv· April 2024

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Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F).
Brecht Creyns, BreAnne MacKenzie, Yago Sa, Ana Lucia Coelho, Dale Christensen

bioRxiv· January 2024

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The ageing lung under stress.
Martina Korfei, BreAnne MacKenzie, Silke Meiners

Eur Respir Rev· June 2020

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Development of an Excipient-Free Peptide Dry Powder Inhalation for the Treatment of Pulmonary Fibrosis.
Yajie Zhang, BreAnne MacKenzie, John J Koleng, Esther Maier, Zachary N Warnken

Mol Pharm· February 2020

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Caveolin-1-derived peptide limits development of pulmonary fibrosis.
Amarnath Satheesh Marudamuthu, Yashodhar Prabhakar Bhandary, Liang Fan, Vijay Radhakrishnan, BreAnne MacKenzie

Sci Transl Med· December 2019

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Montelukast, Leukotriene Inhibitor, Reduces LPS-Induced Acute Lung Inflammation and Human Neutrophil Activation.
Jaime Eduardo Davino-Chiovatto, Manoel Carneiro Oliveira-Junior, BreAnne MacKenzie, Alana Santos-Dias, Ana Roberta Almeida-Oliveira

Arch Bronconeumol (Engl Ed)· November 2019

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Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.
Thomas Stravinskas Durigon, BreAnne MacKenzie, Manoel Carneiro Oliveira-Junior, Alana Santos-Dias, Kátia De Angelis

J Innate Immun· October 2019

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Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.
Martina Korfei, Daniel Stelmaszek, BreAnne MacKenzie, Sylwia Skwarna, Shashipavan Chillappagari

PLoS One· April 2019

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Aerobic exercise inhibits acute lung injury: from mouse to human evidence Exercise reduced lung injury markers in mouse and in cells.
Nicole Cristine Rigonato-Oliveira, BreAnne Mackenzie, Andre Luis Lacerda Bachi, Manoel Carneiro Oliveira-Junior, Alana Santos-Dias

Exerc Immunol Rev· September 2018

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Aerobic exercise inhibits obesity-induced respiratory phenotype.
Jefferson Comin Jonco Aquino-Junior, BreAnne MacKenzie, Ana Roberta Almeida-Oliveira, Ana Carolina Martins, Manoel Carneiro Oliveira-Junior

Cytokine· April 2018

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Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.
Elie El Agha, Alena Moiseenko, Vahid Kheirollahi, Stijn De Langhe, Slaven Crnkovic, BreAnne MacKenzie

Cell Stem Cell· April 2017

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Longevity protein klotho is induced by a single bout of exercise.
Alana Santos-Dias, BreAnne MacKenzie, Manoel Carneiro Oliveira-Junior, Rosa Maria Moyses, Fernanda Marciano Consolim-Colombo

Br J Sports Med· March 2017

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Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.
Elie El Agha, Alena Moiseenko, Vahid Kheirollahi, Stijn De Langhe, Slaven Crnkovic, BreAnne MacKenzie

Cell Stem Cell· February 2017

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Aerobic Exercise Attenuated Bleomycin-Induced Lung Fibrosis in Th2-Dominant Mice.
Adilson Santos Andrade-Sousa, Paulo Rogério Pereira, BreAnne MacKenzie, Manoel Carneiro Oliveira-Junior, Erasmo Assumpção-Neto

PLoS One· September 2016

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Dendritic Cells Are Involved in the Effects of Exercise in a Model of Asthma.
Breanne Mackenzie, Adilson Santos Andrade-Sousa, Manoel Carneiro Oliveira-Junior, Erasmo Assumpção-Neto, Maysa Alves Rodrigues Brandão-Rangel

Med Sci Sports Exerc· August 2016

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Exercise Reduces Lung Fibrosis Involving Serotonin/Akt Signaling.
Paulo Rogerio Pereira, Manoel Carneiro Oliveira-Junior, Breanne Mackenzie, Jaime Eduardo Davino Chiovatto, Yves Matos

Med Sci Sports Exerc· July 2016

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Aerobic Exercise Reduces Asthma Phenotype by Modulation of the Leukotriene Pathway.
Ricardo Wesley Alberca-Custódio, Flávia Regina Greiffo, BreAnne MacKenzie, Manoel Carneiro Oliveira-Junior, Adilson Santos Andrade-Sousa

Front Immunol· July 2016

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Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.
Martina Korfei, Sylwia Skwarna, Ingrid Henneke, BreAnne MacKenzie, Oleksiy Klymenko

Thorax· November 2015

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Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis.
BreAnne MacKenzie, Martina Korfei, Ingrid Henneke, Zaneta Sibinska, Xia Tian

Respir Res· July 2015

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Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair.
BreAnne MacKenzie, Ingrid Henneke, Stefanie Hezel, Denise Al Alam, Elie El Agha

Am J Physiol Lung Cell Mol Physiol· May 2015

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miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development.
Gianni Carraro, Amit Shrestha, Jana Rostkovius, Adriana Contreras, Cho-Ming Chao, Breanne Mackenzie

Development· March 2014

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Fgf10-positive cells represent a progenitor cell population during lung development and postnatally.
Elie El Agha, Susanne Herold, Denise Al Alam, Jennifer Quantius, BreAnne MacKenzie

Development· January 2014

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