Publications by authors named "Brenda Crews"

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Polymeric Nanoparticles Enable Targeted Visualization of Drug Delivery in Breast Cancer.
Md Jashim Uddin, Justin Han-Je Lo, Mukesh K Gupta, Thomas A Werfel, Abu Asaduzzaman, Brenda C Crews

Mol Pharm· May 2025

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Polymeric Micellar Nanoparticles Enable Image-guided Drug Delivery in Solid Tumors.
Jashim Uddin, Justin Han-Je Lo, Mukesh K Gupta, Thomas A Werfel, Abu Asaduzzaman, Brenda C Crews

bioRxiv· February 2025

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Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages.
Ansari M Aleem, Weixi Kang, Shuyang Lin, Matthew Milad, Philip J Kingsley, Brenda C Crews

ACS Chem Biol· February 2023

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Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals.
Md Jashim Uddin, Justin Han-Je Lo, Connor G Oltman, Brenda C Crews, Tamanna Huda

ACS Chem Biol· July 2022

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Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer.
Paola Malerba, Brenda C Crews, Kebreab Ghebreselasie, Cristina K Daniel, Elma Jashim

ACS Med Chem Lett· October 2020

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Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib.
Md Jashim Uddin, Anoop Vemulapalli, Hiroaki Niitsu, Brenda C Crews, Connor G Oltman

ACS Med Chem Lett· October 2020

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Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors.
Md Jashim Uddin, Shu Xu, Brenda C Crews, Ansari M Aleem, Kebreab Ghebreselasie

ACS Med Chem Lett· October 2020

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Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer.
Md Jashim Uddin, Andrew J Wilson, Brenda C Crews, Paola Malerba, Md Imam Uddin

ACS Omega· May 2019

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Prostaglandin E glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y.
Antje Brüser, Anne Zimmermann, Brenda C Crews, Gregory Sliwoski, Jens Meiler

Sci Rep· May 2017

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Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors.
Md Jashim Uddin, Brenda C Crews, Shu Xu, Kebreab Ghebreselasie, Cristina K Daniel

ACS Chem Biol· November 2016

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Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis.
Olivier Boutaud, I Romina Sosa, Taneem Amin, Denise Oram, David Adler, Brenda C Crews

Cancer Prev Res (Phila)· November 2016

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Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization.
Md Jashim Uddin, Chauca E Moore, Brenda C Crews, Cristina K Daniel, Kebreab Ghebreselasie

J Biomed Opt· September 2016

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Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer.
Md Jashim Uddin, Thomas A Werfel, Brenda C Crews, Mukesh K Gupta, Taylor E Kavanaugh

Biomaterials· June 2016

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nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2.
Wilma Neumann, Shu Xu, Menyhárt B Sárosi, Matthias S Scholz, Brenda C Crews

ChemMedChem· January 2016

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Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer.
Andrew J Wilson, Oluwole Fadare, Alicia Beeghly-Fadiel, Deok-Soo Son, Qi Liu, Brenda Crews

Oncotarget· August 2015

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Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe.
Md Jashim Uddin, Brenda C Crews, Kebreab Ghebreselasie, Cristina K Daniel, Philip J Kingsley

J Biomed Opt· May 2015

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Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance.
Wilma Neumann, Brenda C Crews, Menyhárt B Sárosi, Cristina M Daniel, Kebreab Ghebreselasie

ChemMedChem· January 2015

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Fluorescent probes of the apoptolidins and their utility in cellular localization studies.
Sean M DeGuire, David C Earl, Yu Du, Brenda A Crews, Aaron T Jacobs

Angew Chem Int Ed Engl· January 2015

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Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors.
Md Jashim Uddin, Anna V Elleman, Kebreab Ghebreselasie, Cristina K Daniel, Brenda C Crews

ACS Med Chem Lett· November 2014

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Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance.
Wilma Neumann, Brenda C Crews, Lawrence J Marnett, Evamarie Hey-Hawkins

ChemMedChem· June 2014

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PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.
Maria Grazia Perrone, Paola Malerba, Jashim Uddin, Paola Vitale, Andrea Panella, Brenda C Crews

Eur J Med Chem· June 2014

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Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts.
Md Jashim Uddin, Brenda C Crews, Imran Huda, Kebreab Ghebreselasie, Cristina K Daniel

ACS Med Chem Lett· April 2014

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The 2'-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor.
Anna L Blobaum, Md Jashim Uddin, Andrew S Felts, Brenda C Crews, Carol A Rouzer

ACS Med Chem Lett· May 2013

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Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents.
Md Jashim Uddin, Brenda C Crews, Kebreab Ghebreselasie, Lawrence J Marnett

Bioconjug Chem· April 2013

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Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging.
Donald D Nolting, Michael Nickels, Mohammed N Tantawy, James Y H Yu, Jingping Xie, Brenda C Crews

Front Oncol· January 2013

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