Publications by authors named "Brenda D Moore"

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Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
Yona Levites, Eric B Dammer, Yong Ran, Wangchen Tsering, Duc Duong, Brenda D Moore

Cell Rep Med· August 2024

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Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region.
Giavanna Paterno, Brenda D Moore, Brach M Bell, Kimberly-Marie M Gorion, Yong Ran

Antibodies (Basel)· August 2024

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A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies.
Brenda D Moore, Yong Ran, Marshall S Goodwin, Kavitha Komatineni, Karen N McFarland

Mol Ther Methods Clin Dev· December 2023

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Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.
Yona Levites, Eric B Dammer, Yong Ran, Wangchen Tsering, Duc Duong, Brenda Dawn Moore

bioRxiv· December 2023

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Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts.
Brenda D Moore, Yona Levites, Guilian Xu, Hailey Hampton, Munir F Adamo

Free Neuropathol· January 2022

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Remodeling Alzheimer-amyloidosis models by seeding.
Brittany S Ulm, David R Borchelt, Brenda D Moore

Mol Neurodegener· February 2021

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Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.
Lorena De Mena, Michael A Smith, Jason Martin, Katie L Dunton, Carolina Ceballos-Diaz, Brenda D Moore

Alzheimers Res Ther· October 2020

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An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
Hunter S Futch, Karen N McFarland, Brenda D Moore, M Zino Kuhn, Benoit I Giasson

J Exp Med· November 2019

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TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.
Paramita Chakrabarty, Andrew Li, Thomas B Ladd, Michael R Strickland, Emily J Koller, Brenda D Moore

J Exp Med· September 2018

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Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.
Cara L Croft, Brenda D Moore, Yong Ran, Paramita Chakrabarty, Yona Levites

PLoS One· July 2018

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Short Aβ peptides attenuate Aβ42 toxicity in vivo.
Brenda D Moore, Jason Martin, Lorena de Mena, Jonatan Sanchez, Pedro E Cruz

J Exp Med· January 2018

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A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies.
Jess-Karan S Dhillon, Cara Riffe, Brenda D Moore, Yong Ran, Paramita Chakrabarty

PLoS One· October 2017

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Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.
Kevin H Strang, Marshall S Goodwin, Cara Riffe, Brenda D Moore, Paramita Chakrabarty

Acta Neuropathol Commun· July 2017

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Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein.
Nicola J Rutherford, Brenda D Moore, Todd E Golde, Benoit I Giasson

J Neurochem· December 2014

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Steroids as γ-secretase modulators.
Joo In Jung, Thomas B Ladd, Thomas Kukar, Ashleigh R Price, Brenda D Moore

FASEB J· September 2013

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Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis.
Guilian Xu, Stanley M Stevens, Brenda D Moore, Scott McClung, David R Borchelt

Hum Mol Genet· July 2013

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Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.
Tatiana Melnikova, Susan Fromholt, HyunSu Kim, Deidre Lee, Guilian Xu, Brenda D Moore

J Neurosci· February 2013

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Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).
Hyo-Jin Park, Daniil Shabashvili, Michael D Nekorchuk, Eva Shyqyriu, Joo In Jung, Brenda D Moore

J Biol Chem· November 2012

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Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.
Brenda D Moore, Paramita Chakrabarty, Yona Levites, Tom L Kukar, Ann-Marie Baine

Alzheimers Res Ther· May 2012

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Biophysical analyses of synthetic amyloid-beta(1-42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous amyloid-beta oligomers.
Brenda D Moore, Vijayaraghavan Rangachari, William M Tay, Nicole M Milkovic, Terrone L Rosenberry

Biochemistry· December 2009

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Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.
Vijayaraghavan Rangachari, Zachary S Davey, Brent Healy, Brenda D Moore, Leilani K Sonoda

Biopolymers· June 2009

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BRI2 (ITM2b) inhibits Abeta deposition in vivo.
Jungsu Kim, Victor M Miller, Yona Levites, Karen Jansen West, Craig W Zwizinski, Brenda D Moore

J Neurosci· June 2008

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Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate.
Vijayaraghavan Rangachari, Brenda D Moore, Dana Kim Reed, Leilani K Sonoda, Alexander W Bridges

Biochemistry· October 2007

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Secondary structure and interfacial aggregation of amyloid-beta(1-40) on sodium dodecyl sulfate micelles.
Vijayaraghavan Rangachari, Dana Kim Reed, Brenda D Moore, Terrone L Rosenberry

Biochemistry· July 2006

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