Publications by authors named "Bret D Wallace"

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Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Jessica S Williams, Jessica L Wojtaszek, Denise C Appel, Juno Krahn, Bret D Wallace

Cell Rep· October 2022

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Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity.
Anup P Challa, Xin Hu, Ya-Qin Zhang, Jeffrey Hymes, Bret D Wallace

J Chem Inf Model· April 2022

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Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
Alejandro Álvarez-Quilón, Jessica L Wojtaszek, Marie-Claude Mathieu, Tejas Patel, C Denise Appel, Bret D Wallace

Mol Cell· June 2020

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Targeting the pregnane X receptor using microbial metabolite mimicry.
Zdeněk Dvořák, Felix Kopp, Cait M Costello, Jazmin S Kemp, Hao Li, Bret D Wallace

EMBO Mol Med· April 2020

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Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Aadra P Bhatt, Samuel J Pellock, Kristen A Biernat, William G Walton, Bret D Wallace

Proc Natl Acad Sci U S A· March 2020

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APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.
Bret D Wallace, Zachary Berman, Geoffrey A Mueller, Yunfeng Lin, Timothy Chang

Proc Natl Acad Sci U S A· January 2017

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Structure of the sirtuin-linked macrodomain SAV0325 from Staphylococcus aureus.
C Denise Appel, Geoffrey K Feld, Bret D Wallace, R Scott Williams

Protein Sci· September 2016

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Ribonucleotide triggered DNA damage and RNA-DNA damage responses.
Bret D Wallace, R Scott Williams

RNA Biol· October 2015

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Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Bret D Wallace, Adam B Roberts, Rebecca M Pollet, James D Ingle, Kristen A Biernat

Chem Biol· September 2015

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Recognition and repair of chemically heterogeneous structures at DNA ends.
Sara N Andres, Matthew J Schellenberg, Bret D Wallace, Percy Tumbale, R Scott Williams

Environ Mol Mutagen· January 2015

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Molecular insights into microbial β-glucuronidase inhibition to abrogate CPT-11 toxicity.
Adam B Roberts, Bret D Wallace, Madhu Kumar Venkatesh, Sridhar Mani, Matthew R Redinbo

Mol Pharmacol· August 2013

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Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα.
Bret D Wallace, Laurie Betts, Garrick Talmage, Rebecca M Pollet, Natalie S Holman

J Mol Biol· July 2013

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The human microbiome is a source of therapeutic drug targets.
Bret D Wallace, Matthew R Redinbo

Curr Opin Chem Biol· June 2013

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Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective.
Bret D Wallace, Matthew R Redinbo

Drug Metab Rev· February 2013

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Turnover-dependent covalent inactivation of Staphylococcus aureus coenzyme A-disulfide reductase by coenzyme A-mimetics: mechanistic and structural insights.
Bret D Wallace, Jonathan S Edwards, Jamie R Wallen, Wessel J A Moolman, Renier van der Westhuyzen

Biochemistry· October 2012

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Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice.
Amanda LoGuidice, Bret D Wallace, Lauren Bendel, Matthew R Redinbo, Urs A Boelsterli

J Pharmacol Exp Ther· May 2012

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Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.
Bret D Wallace, Hongwei Wang, Kimberly T Lane, John E Scott, Jillian Orans

Science· November 2010

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Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis .
Derek Parsonage, Gerald L Newton, Robert C Holder, Bret D Wallace, Carleitta Paige

Biochemistry· September 2010

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Hydration changes accompanying the binding of minor groove ligands with DNA.
Natalya N Degtyareva, Bret D Wallace, Andrea R Bryant, Kristine M Loo, Jeffrey T Petty

Biophys J· February 2007

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